Clinical Manuals

Comprehensive list of drugs and conditions causing QT prolongation, torsade de pointes (TdP) and long QT syndrome (LQTS)

Contents

A comprehensive list of conditions and drugs that may prolong the QT interval, cause torsade de pointes (TdP) and long QT syndrom (LQTS) is presented below. With regards to drugs, the risk of QT prolongation and TdP varies markedly across the list but tends to be rather similar within a drug class. While the risk of TdP is well-defined for many of these agents, many are classified as QT-prolonging solely based on their drug class or presumed pharmacodynamic effects. We provide a direct PubMed search for each drug and we recommend the reader to use this link to assess the literature.

Medical conditions

CategoryCondition
Congenital conditionsJervell and Lange-Nielsen syndrome
Romano-Ward syndrome
Idiopathic congenital long QT syndrome (LQTS)
Metabolic disordersHypokalemia
Hypomagnesemia
Hypocalcemia
Starvation
Anorexia nervosa
Liquid protein diets
Hypothyroidism
BradyarrhythmiaSinus bradycardia
Sinus node dysfunction
AV-blocks

Drugs

DrugBrandsTdP RiskClassClinical UseDrugbank DescriptionPubmed RecordDrugBank Record
AbarelixPlenaxisClassified as QT prolonging drug in DrugBank. No data on QT prolongation or risk of torsade de pointes in PubMed.GnRH AntagonistCancer (prostate)Synthetic decapeptide antagonist to gonadotropin releasing hormone (GnRH).PubMed search AbarelixDrugBank search Abarelix
Abexinostat NoneClassified as QT prolonging drug in DrugBank. No data on QT prolongation or risk of torsade de pointes in PubMed.  Abexinostat has been used in trials studying the treatment of Sarcoma, Lymphoma, Leukemia, Lymphocytic, and Hodgkin Disease, among others. It is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase…PubMed search AbexinostatDrugBank search Abexinostat
AbirateroneZytiga, Abiratas, Abretone, AbiraproSeveral cases of QT prolongation and torsade de pointes reported to the FDA in postmarketing studies.Anti-androgenCancer (Prostate)Abiraterone is an antiandrogen used in the treatment of prostate cancer.PubMed search AbirateroneDrugBank search Abiraterone
Aceprometazine NoneClassified as QT prolonging drug in DrugBank. No data on QT prolongation or risk of torsade de pointes in PubMed.Drug with neuroleptic and anti-histamine properties.Sleep disorder Aceprometazine is often used in combination with meprobamate for the treatment of sleep disorders.PubMed search AceprometazineDrugBank search Aceprometazine
Acetyldigoxin Classified as QT prolonging drug in DrugBank. No data on QT prolongation or risk of torsade de pointes in PubMed.  PubMed search AcetyldigoxinDrugBank search Acetyldigoxin
AclarubicinAclarubicinSeveral cases of QT prolongation and ventricular fibrillation have been reported. See PubMed link.   PubMed search AclarubicinDrugBank search Aclarubicin
Acrivastine QT prolongation has been described (see PubMed link).  An antihistamine agent used for the symptomatic relief of seasonal allergic rhinitis, rhinorrhea, pruritus, lacrimation, and nasal congestion.PubMed search AcrivastineDrugBank search Acrivastine
Ajmaline AjimalinFew cases with torsade de pointes described (see PubMed link).Class IA antiarrhythmicArrhythmiasAn antiarrhythmic used to manage several tachycardias.PubMed search Ajmaline

Kaul et al
Haverkamp et al
DrugBank search Ajmaline
Albuterol (Salbutamol)Proventil, Ventolin, Ventolin-HFA, Accuneb, Combivent, Vospire-ER, ProAir HFA, DuonebLow riskBronchodilatorAsthmaBeta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms PubMed search Albuterol (salbutamol)DrugBank search Albuterol (salbutamol)
AlfuzosinUroxatralLow to moderate riskAlpha-1 adrenergic blockerBenign prostatic hyperplasiaAn alpha-1 adrenergic antagonist used in the symptomatic management of benign prostatic hypertrophy (BPH).PubMed search AlfuzosinDrugBank search Alfuzosin
Alimemazine PanectylClassified as QT prolonging drug in Drugbank  An antihistamine agent used to prevent and relieve allergic conditions which cause pruritus and other allergic skin conditions, including urticaria.PubMed search AlimemazineDrugBank search Alimemazine
Alimemazine (Trimeprazine)PanectylLow to moderate risk AntihistamineAllergic reactions PubMed search Alimemazine (Trimeprazine)DrugBank search Alimemazine (Trimeprazine)
AmantadineSymmetrel, Symadine, Gocovri, OsmolexLow to moderate riskAntiviralViral infection (Influenza), Parkinson’s diseaseA medication used to treat dyskinesia in Parkinson’s patients receiving levodopa, as well as extrapyramidal side effects of medications.PubMed search AmantadineDrugBank search Amantadine
AmifampridineFirdapse, RuzurgiClassified as QT prolonging drug. No cases described in PubMed (see link). Presumably low risk.  A voltage gated potassium channel blocker used to treat Lambert-Eaton myasthenic syndrome.PubMed search AmifampridineDrugBank search Amifampridine
AmiodaroneCordarone, Pacerone, NexteroneFrequently causes non-significant QT prolongaton. Rarely causes torsade de pointes. Low risk in patients without propensity for QT prolongation.Class III AntiarrhythmicArrhythmiaA class III antiarrhythmic indicated for the treatment of ventricular premature beats, ventricular tachycardia and ventricular fibrillation.PubMed search AmiodaroneDrugBank search Amiodarone
AmisulprideBarhemsys, Solian, Supitac, Soltus, Amitrex, AmazeoLow to moderate risk (with IV use)Antiemetic, AntipsychoticNausea and vomiting, postoperativeDopamine D2 receptor antagonist used in the treatment of acute and chronic schizophrenia, and in the prevention and treatment of postoperative nausea and vomiting in adults.PubMed search AmisulprideDrugBank search Amisulpride
AmitriptylineElavil, Tryptomer, Tryptizol, Laroxyl, Saroten, Sarotex Lentizol, EndepAmitriptyline has been reported to induce long QT syndrome and Brugada syndrome (see PubMed link).Antidepressant, TricyclicDepressionA tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety.PubMed search AmitriptylineDrugBank search Amitriptyline
Amodiaquine Data on amodiaquine are scarce, although transient effects on cardiac electrophysiology (QT interval prolongation and sinus bradycardia) have been observed (see PubMed link).Antimalarial drug.Antimalarial drug.Antimalarial drug.PubMed search AmodiaquineDrugBank search Amodiaquine
AmoxapineAmoxapineAmoxapine has been linked to cases of QT prolongation, acute heart failure, and sudden death (See PubMed links)  A tricyclic antidepressant used in the treatment of neurotic or reactive depressive disorders and endogenous or psychotic depression.PubMed search AmoxapineDrugBank search Amoxapine
Amphetamine (Amfetamine)Adderal-XR, Dexedrine, Dextroamp, Adderall, Adzenys, Dyanavel, Evekeo, MydayisModerate risk.CNS stimulantADHDCNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).PubMed search Amphetamine (Amfetamine)DrugBank search Amphetamine (Amfetamine)
Amphotericin BFungilin, Fungizone, Abelcet, AmBisome, Fungisome, Amphocil, AmphotecSeveral cases of QT prolongation and torsade de pointes described (see PubMed link).AntifungalFungal infectionAntifungal used in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis.PubMed search Amphotericin BDrugBank search Amphotericin B
Amsacrine (Acridinyl anisidide)AmsidineClassified as QT prolonging drugAntineoplastic AgentCancer (Acute Lymphoblastic Leukemia) PubMed search Amsacrine (Acridinyl anisidide)DrugBank search Amsacrine (Acridinyl anisidide)
AnagrelideAgrylin, XagridLow to moderate riskPhosphodiesterase 3 inhibitorThrombocythemiaA platelet-reducing agent used to treat thrombocythemia, and its related complications, secondary to myeloproliferative neoplasms.PubMed search AnagrelideDrugBank search Anagrelide
Anisodamine Classified as QT prolonging drug  Anisodamine has been investigated for the treatment of Intestinal Diseases.PubMed search AnisodamineDrugBank search Anisodamine
Antazoline Classified as QT prolonging drug  An antihistamine agent used for the symptomatic treatment of nasal congestion and allergic conjunctivitis.PubMed search AntazolineDrugBank search Antazoline
ApalutamideErleadaClassified as QT prolonging drugnonsteroidal antiandrogenCancer (prostate) PubMed search ApalutamideDrugBank search Apalutamide
ApomorphineApokyn, Ixense, Spontane, UprimaLow to moderate riskDopamine agonistParkinson’s diseaseA morphine derivative D2 dopamine agonist used to treat hypomobile “off” episodes of advanced Parkinson’s disease.PubMed search ApomorphineDrugBank search Apomorphine
Aranidipine Classified as QT prolonging drug  Aranidipine has been used for many years to treat angina pectoris and hypertension.PubMed search AranidipineDrugBank search Aranidipine
ArformoterolBrovanaLow riskBronchodilatorAsthma, COPDA beta-2 adrenergic agonist and bronchodilator used for long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.PubMed search ArformoterolDrugBank search Arformoterol
AripiprazoleAbilify, AripiprexClassified as QT prolonging drugAntipsychotic, atypicalSchizophrenia, depression (adjunct)An atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette’s syndrome.PubMed search AripiprazoleDrugBank search Aripiprazole
Aripiprazole lauroxil Classified as QT prolonging drug  An antipsychotic used to treat schizophrenia in adults.PubMed search Aripiprazole lauroxilDrugBank search Aripiprazole lauroxil
Arsenic trioxideTrisenoxHigh riskAnti-cancerCancer (leukemia)A chemotherapeutic agent used in the treatment of refractory or relapsed acute promyelocytic leukemia in patients with prior retinoid and anthracycline chemotherapy.PubMed search Arsenic trioxideDrugBank search Arsenic trioxide
Artemether Classified as QT prolonging drug  An antimalarial agent used in combination with lumefantrine for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum.PubMed search ArtemetherDrugBank search Artemether
Artemether LumefantrineCoartemLow riskAnti-malarialMarlaria PubMed search Artemether LumefantrineDrugBank search Artemether Lumefantrine
Artenimol / PiperaquineEurartesimModerate riskAntimalarialMalaria PubMed search Artenimol / PiperaquineDrugBank search Artenimol / Piperaquine
AsenapineSaphris, SycrestLow to moderate riskAntipsychotic, atypicalSchizophreniaAn atypical antipsychotic used to treat patients with bipolar I disorder and patients with schizophrenia.PubMed search AsenapineDrugBank search Asenapine
AstemizoleHismanalClassified as QT prolonging drugAntihistamineAllergic rhinitisA second generation antihistamine used to treat allergy symptoms.PubMed search AstemizoleDrugBank search Astemizole
AtazanavirReyataz, EvotazClassified as QT prolonging drugAntiviralViral infection (HIV/AIDS)An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV.PubMed search AtazanavirDrugBank search Atazanavir
AtomoxetineStratteraLow to moderate riskCNS stimulantADHDA selective norepinephrine reuptake inhibitor (SNRI) used in the management of Attention Deficit Hyperactivity Disorder (ADHD).PubMed search AtomoxetineDrugBank search Atomoxetine
Azatadine Classified as QT prolonging drug  An H1 receptor antagonist used to treat perennial and allergic rhinitis as well as eustachian tube congestion.PubMed search AzatadineDrugBank search Azatadine
Azimilide Classified as QT prolonging drug  Investigated for use/treatment in arrhythmia and atrial fibrillation.PubMed search AzimilideDrugBank search Azimilide
AzithromycinZithromax, ZmaxModerate riskAntibioticBacterial infectionA macrolide antibiotic used to treat a variety of bacterial infections.PubMed search AzithromycinDrugBank search Azithromycin
BedaquilineSirturoHigh riskAntibioticTuberculosis, Multi-drug resistantA diarylquinoline antimycobacterial used in combination with other antibacterials to treat pulmonary multidrug resistant tuberculosis (MDR-TB).PubMed search BedaquilineDrugBank search Bedaquiline
BendamustineTreanda, Treakisym, Ribomustin, LevactClassified as QT prolonging drugAnti-cancerCancer (Leukemia, lymphoma) PubMed search BendamustineDrugBank search Bendamustine
Bendroflumethiazide / BendrofluazideAprinox, CorzideClassified as QT prolonging drugDiuretic, thiazideHypertension, diuresis PubMed search Bendroflumethiazide / BendrofluazideDrugBank search Bendroflumethiazide / Bendrofluazide
Benzatropine Classified as QT prolonging drug  An anticholinergic drug used to treat Parkinson’s disease (PD) and extrapyramidal symptoms, except tardive dyskinesia.PubMed search BenzatropineDrugBank search Benzatropine
BenzphetamineDidrex, RecedeClassified as QT prolonging drug Obesity PubMed search BenzphetamineDrugBank search Benzphetamine
BepridilVascorHigh riskAntianginalAngina Pectoris (heart pain)For the treatment of hypertension, and chronic stable angina (classic effort-associated angina).PubMed search BepridilDrugBank search Bepridil
Berotralstat Classified as QT prolonging drug  An inhibitor of plasma kallikrein used for prophylaxis of angioedema attacks in patients with hereditary angioedema.PubMed search BerotralstatDrugBank search Berotralstat
Besifloxacin Classified as QT prolonging drug  A fluoroquinolone antibiotic agent used for the treatment of bacterial conjunctivitis.PubMed search BesifloxacinDrugBank search Besifloxacin
BetrixabanBevyxxaClassified as QT prolonging drugAnticoagulantAnticoagulant PubMed search BetrixabanDrugBank search Betrixaban
BicalutamideCasodexClassified as QT prolonging drugAnti-androgenCancer (prostate) PubMed search BicalutamideDrugBank search Bicalutamide
BilastineBlextenClassified as QT prolonging drugAntihistaminesAntihistamines PubMed search BilastineDrugBank search Bilastine
BortezomibVelcade, BortecadClassified as QT prolonging drugProteasome inhibitorCancer (multiple myeloma,lymphoma)A proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies.PubMed search BortezomibDrugBank search Bortezomib
BosutinibBosulifLow riskAnti-cancerCancer (leukemia) PubMed search BosutinibDrugBank search Bosutinib
Buclizine Classified as QT prolonging drug  An antihistamine and antiemetic drug for the treatment of allergy symptoms and prevention of nausea and vomiting.PubMed search BuclizineDrugBank search Buclizine
Bunaftine Classified as QT prolonging drug  Not AnnotatedPubMed search BunaftineDrugBank search Bunaftine
Bupranolol Classified as QT prolonging drug  Used to manage hypertension and tachycardia. Also used to treat glaucoma.PubMed search BupranololDrugBank search Bupranolol
BuprenorphineButrans, Belbuca, Bunavail, Buprenex, Subutex, Suboxone, ZubsolvLow riskOpioid agonistNarcotic dependence, pain PubMed search BuprenorphineDrugBank search Buprenorphine
Buserelin Classified as QT prolonging drug  A LHRH agonist used for the palliative treatment of hormone-dependent advanced carcinoma of the prostate gland in males and treatment of endometriosis in females.PubMed search BuserelinDrugBank search Buserelin
Butriptyline Classified as QT prolonging drug  Butriptyline is a tricyclic antidepressant which has been used in Europe since 1974. It is the isobutyl side chain homologue of amitriptyline.PubMed search ButriptylineDrugBank search Butriptyline
CabozantinibCometriqClassified as QT prolonging drugAnti-cancerCancer (renal cell) PubMed search CabozantinibDrugBank search Cabozantinib
CapecitabineXelodaModerate riskAnti-cancerCancer (GI, Breast) PubMed search CapecitabineDrugBank search Capecitabine
CarbetocinPabal, Lonactene, DuratocinModerate riskuterotonicUterine atony PubMed search CarbetocinDrugBank search Carbetocin
Cariporide Classified as QT prolonging drug  Investigated for use/treatment in cardiac surgery.PubMed search CariporideDrugBank search Cariporide
CeritinibZykadiaModerate riskAnti-cancerCancer (Lung)An antineoplastic kinase inhibitor used to treat anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) in patients with inadequate clinical response or intolerance to crizotinib.PubMed search CeritinibDrugBank search Ceritinib
Cesium ChlorideEnergy CatalystClassified as QT prolonging drugtoxinAlternative therapy cancer PubMed search Cesium ChlorideDrugBank search Cesium Chloride
Chloral hydrateAquachloral, Novo-Chlorhydrate, Somnos, Noctec, SomnoteClassified as QT prolonging drugSedativeSedation, insomnia PubMed search Chloral hydrateDrugBank search Chloral hydrate
Chlorcyclizine Classified as QT prolonging drug  Chlorcyclizine is a first generation phenylpiperazine class antihistamine used to treat urticaria, rhinitis, pruritus, and other allergy symptoms. Chlorcyclizine also has some local anesthetic, anticholinergic, and antiserotonergic properties, and can…PubMed search ChlorcyclizineDrugBank search Chlorcyclizine
ChloroquineAralenModerate riskAntimalarialMalariaAn antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis.PubMed search ChloroquineDrugBank search Chloroquine
ChlorpromazineThorazine, Largactil, MegaphenHigh riskAntipsychotic / AntiemeticPsychosis, nausea, many othersA phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children.PubMed search ChlorpromazineDrugBank search Chlorpromazine
ChlorprothixeneTruxalClassified as QT prolonging drugAntipsychoticSchizophrenia PubMed search ChlorprothixeneDrugBank search Chlorprothixene
Cibenzoline Classified as QT prolonging drug  Not AnnotatedPubMed search CibenzolineDrugBank search Cibenzoline
Cicletanine Classified as QT prolonging drug  Cicletanine is under investigation for the treatment of Diabetes, Hypokalemia, Hyponatremia, and Arterial Hypertension.PubMed search CicletanineDrugBank search Cicletanine
CilostazolPletalClassified as QT prolonging drugPhosphodiesterase 3 inhibitorIntermittent claudicationAn antiplatelet agent and vasodilator used for the symptomatic relief of intermittent claudication.PubMed search CilostazolDrugBank search Cilostazol
CimetidineTagametClassified as QT prolonging drugAntacidGastric hyperacidity, GERD PubMed search CimetidineDrugBank search Cimetidine
Cinoxacin Classified as QT prolonging drug  For the treatment of initial and recurrent urinary tract infections in adults caused by the following susceptible microorganisms: Escherichia coli, Proteus mirabilis, Proteus vulgaris, Klebsiella species (including K. pneumoniae), and…PubMed search CinoxacinDrugBank search Cinoxacin
CiprofloxacinCipro, Cipro-XR, NeofloxinLow to moderate riskAntibioticBacterial infectionA second generation fluoroquinolone used to treat various susceptible bacterial infections.PubMed search CiprofloxacinDrugBank search Ciprofloxacin
CisapridePropulsidHigh riskGI stimulantIncrease GI motilityA medication used to treat heartburn associated with GERD.PubMed search CisaprideDrugBank search Cisapride
CitalopramCelexa, CipramilModerate riskAntidepressant, SSRIDepressionA selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression.PubMed search CitalopramDrugBank search Citalopram
ClarithromycinBiaxin, PrevpacModerate riskAntibioticBacterial infectionA macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection.PubMed search ClarithromycinDrugBank search Clarithromycin
Clemastine Classified as QT prolonging drug  An antihistamine with sedative and anticholinergic effects used to treat the symptoms of allergic rhinitis.PubMed search ClemastineDrugBank search Clemastine
ClofazimineLampreneModerate riskAntibioticLeprosy PubMed search ClofazimineDrugBank search Clofazimine
ClomipramineAnafranilModerate riskAntidepressant, TricyclicDepressionA tricyclic antidepressant used in the treatment of obsessive-compulsive disorder and disorders with an obsessive-compulsive component, such as depression, schizophrenia, and Tourette’s disorder.PubMed search ClomipramineDrugBank search Clomipramine
ClotiapineClotiapineClassified as QT prolonging drug   PubMed search ClotiapineDrugBank search Clotiapine
ClozapineClozaril, Fazaclo, VersaclozModerate riskAntipsychotic, atypicalSchizophreniaAn antipsychotic drug used in treatment resistant schizophrenia and to decrease suicide risk in schizophrenic patients.PubMed search ClozapineDrugBank search Clozapine
CobimetinibCotellicClassified as QT prolonging drugAnti-cancerCancer (Melanoma) PubMed search CobimetinibDrugBank search Cobimetinib
CocaineCocaineLow to moderate risk with topical useLocal anestheticAnesthesia (topical)An ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities.PubMed search CocaineDrugBank search Cocaine
Coumaphos Classified as QT prolonging drug  This drug is a fat-soluble phosphorothioate agent that kills both insects and mites. It is non-volatile in nature and is well known by a variety of names as such a…PubMed search CoumaphosDrugBank search Coumaphos
CrizotinibXalkoriModerate riskAnti-cancerCancer (Non-small cell lung cancer, metastatic)A receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive.PubMed search CrizotinibDrugBank search Crizotinib
CUDC-101 Classified as QT prolonging drug  CUDC-101 has been used in trials studying the treatment of Cancer, Tumors, Liver Cancer, Breast Cancer, and Gastric Cancer, among others.PubMed search CUDC-101DrugBank search CUDC-101
CUDC-907 Classified as QT prolonging drug  CUDC-907 has been used in trials studying the treatment of Lymphoma, Solid Tumors, BREAST CANCER, Multiple Myeloma, and NUT Midline Carcinoma, among others.PubMed search CUDC-907DrugBank search CUDC-907
Cyamemazine (Cyamepromazine)TercianClassified as QT prolonging drugAntipsychoticSchizophrenia, sedation PubMed search Cyamemazine (Cyamepromazine)DrugBank search Cyamemazine (Cyamepromazine)
Cyclizine Classified as QT prolonging drug  An antihistamine and antiemetic drug used for the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo.PubMed search CyclizineDrugBank search Cyclizine
DabrafenibTafinlarModerate riskAnti-cancerCancer (melanoma)A kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.PubMed search DabrafenibDrugBank search Dabrafenib
DasatinibSprycelModerate riskAnti-cancerCancer (leukemia)A tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy.PubMed search DasatinibDrugBank search Dasatinib
DegarelixFirmagon, FerringClassified as QT prolonging drugAnti-androgenCancer (prostate)A GnRH receptor antagonist used in the management of advanced prostate cancer.PubMed search DegarelixDrugBank search Degarelix
DelamanidDeltybaHigh riskAntibioticTuberculosis, Multi-drug resistantAn antibiotic used to treat multidrug resistant tuberculosis.PubMed search DelamanidDrugBank search Delamanid
Desflurane Classified as QT prolonging drug  A general inhalation anesthetic for inpatient and outpatient surgery in adults.PubMed search DesfluraneDrugBank search Desflurane
DesipraminePertofrane, NorpramineClassified as QT prolonging drugAntidepressant, TricyclicDepressionA tricyclic antidepressant used in the treatment of depression.PubMed search DesipramineDrugBank search Desipramine
DeutetrabenazineAustedoLow to moderate riskVMAT2 inhibitorHuntington’s disease PubMed search DeutetrabenazineDrugBank search Deutetrabenazine
Dexbrompheniramine Classified as QT prolonging drug  An antihistamine used to treat allergy symptoms including upper respiratory tract symptoms.PubMed search DexbrompheniramineDrugBank search Dexbrompheniramine
DexmedetomidineDexdor, Igalmi, PrecedexLow riskAnesthetic, generalAnesthesia PubMed search DexmedetomidineDrugBank search Dexmedetomidine
DexmethylphenidateFocalin, Focalin-XR, AttenadeClassified as QT prolonging drugCNS stimulantADHD PubMed search DexmethylphenidateDrugBank search Dexmethylphenidate
Dextroamphetamine (dexamfetamine)Dexedrine, dexamphetamine, dexamfetamine, (S)-(+)-amphetamine, Dextrostat, Dexedrine, Metamina, Attentin, Zenzedi, Procentra, AmfexaClassified as QT prolonging drugCNS stimulantADHD, obesity PubMed search Dextroamphetamine (dexamfetamine)DrugBank search Dextroamphetamine (dexamfetamine)
Dextromethorphan QuinidinefloxuridineHigh riskUnknownPseudobulbar affect PubMed search Dextromethorphan QuinidineDrugBank search Dextromethorphan Quinidine
Dexverapamil Classified as QT prolonging drug  Not AnnotatedPubMed search DexverapamilDrugBank search Dexverapamil
Dichlorvos Classified as QT prolonging drug  Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products…PubMed search DichlorvosDrugBank search Dichlorvos
Diethylpropion (amfepramone)Tenuate, TepanilClassified as QT prolonging drugSympathomimeticObesity PubMed search Diethylpropion (amfepramone)DrugBank search Diethylpropion (amfepramone)
Difloxacin Classified as QT prolonging drug  Difloxacin is a synthetic fluoroquinolone used in veterinary. As an antibacterial, it presents a broad bactericidal spectrum and its effects are dependent on its concentration. However, it presents a reduced…PubMed search DifloxacinDrugBank search Difloxacin
DiltiazemCardizemClassified as QT prolonging drugCalcium channel blockerHypertension PubMed search DiltiazemDrugBank search Diltiazem
DiphenhydramineBenadryl, Nytol, Unisom, Sominex, Dimedrol, Daedalon, BanophenClassified as QT prolonging drugAntihistamineAllergic rhinitis, insomniaA H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.PubMed search DiphenhydramineDrugBank search Diphenhydramine
DisopyramideNorpaceClassified as QT prolonging drugAntiarrhythmicArrhythmiaA class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias.PubMed search DisopyramideDrugBank search Disopyramide
DobutamineDobutrexClassified as QT prolonging drugInotropeHeart failure, shock (low blood pressure) PubMed search DobutamineDrugBank search Dobutamine
DofetilideTikosynClassified as QT prolonging drugAntiarrhythmicArrhythmiaA class III antiarrhythmic drug used for the maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter.PubMed search DofetilideDrugBank search Dofetilide
DolasetronAnzemetLow to moderate riskAntiemeticNausea, vomitingAn antinauseant and antiemetic used in chemotherapy and postoperatively.PubMed search DolasetronDrugBank search Dolasetron
DomperidoneMotilium, Motillium, Motinorm Costi, NomitModerate riskAntiemeticNausea, vomitingA dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting.PubMed search DomperidoneDrugBank search Domperidone
DonepezilAriceptLow to moderate riskCholinesterase inhibitorDementia (Alzheimer’s Disease) PubMed search DonepezilDrugBank search Donepezil
DopamineIntropineClassified as QT prolonging drugInotropeHeart failure, shock (low blood pressure) PubMed search DopamineDrugBank search Dopamine
DoxepinSinequan, Silenor, Aponal, Adapine, Doxal, Deptran, SinquanModerate riskAntidepressant, TricyclicDepressionA psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia.PubMed search DoxepinDrugBank search Doxepin
Doxylamine Classified as QT prolonging drug  An antihistamine used to treat insomnia and allergy symptoms and is used with pyridoxine in the treatment of nausea and vomiting in pregnancy.PubMed search DoxylamineDrugBank search Doxylamine
DronedaroneMultaqClassified as QT prolonging drugAntiarrhythmicArrhythmiaAn antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation.PubMed search DronedaroneDrugBank search Dronedarone
DroperidolInapsine, Droleptan, Dridol, XomolixModerate riskAntipsychotic / AntiemeticAnesthesia (adjunct), nauseaA butyrophenone derivative and dopamine antagonist used to prevent and treat postoperative nausea and vomiting.PubMed search DroperidolDrugBank search Droperidol
DroxidopaNortheraClassified as QT prolonging drugAdrenergic pro-drugHypotension (Neurogenic orthostatic) PubMed search DroxidopaDrugBank search Droxidopa
Echothiophate Classified as QT prolonging drug  An acetylcholinesterase inhibitor used in ophthalmic preparations to increase the drainage of intraocular fluid; most commonly used for the treatment of glaucoma.PubMed search EchothiophateDrugBank search Echothiophate
EfavirenzSustivaLow to moderate riskAntiviralHIV/AIDS PubMed search EfavirenzDrugBank search Efavirenz
Efonidipine Classified as QT prolonging drug  For the treatment of hypertension.PubMed search EfonidipineDrugBank search Efonidipine
EliglustatCerdelgaLow to moderate riskGlucosylceramide synthase inhibitorGaucher’s diseaseA glucosylceramide synthase used to treat type 1 Gaucher disease in patients who are CYP2D6 extensive, intermediate, or poor metabolizers.PubMed search EliglustatDrugBank search Eliglustat
Encainide Classified as QT prolonging drug  A voltage-gated sodium channel blocker used for management of atrial or ventricular fibrillation, atrial flutter, and ventricular tachycardia, that is no longer used due to proarrhythmic adverse effects.PubMed search EncainideDrugBank search Encainide
EncorafenibBraftoviModerate riskBRAF inhibitorCancer (Melanoma) PubMed search EncorafenibDrugBank search Encorafenib
Enoxacin Classified as QT prolonging drug  For the treatment of adults (≥18 years of age) with the following infections caused by susceptible strains of the designated microorganisms: (1) uncomplicated urethral or cervical gonorrhea due to Neisseria…PubMed search EnoxacinDrugBank search Enoxacin
Entinostat Classified as QT prolonging drug  Entinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers, and Normal Volunteers. Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic…PubMed search EntinostatDrugBank search Entinostat
EntrectinibRozlytrekClassified as QT prolonging drugAnti-cancerCancer (Lung)Entrectinib is indicated for the treatment of metastatic ROS1-positive non-small cell lung cancer in adults. Entrectinib is also indicated in adults and children over 12 years old for the treatment…PubMed search EntrectinibDrugBank search Entrectinib
EperisoneEperisoneClassified as QT prolonging drug  An antispasmodic that functions through voltage-gated channel blockade, notably with little to no sedation, effective in relaxing skeletal muscles and vascular smooth muscles.PubMed search EperisoneDrugBank search Eperisone
EphedrineRynatuss, BroncholateClassified as QT prolonging drugBronchodilator, decongestantAllergic reaction, allergic rhinitis, asthma PubMed search EphedrineDrugBank search Ephedrine
Epinastine Classified as QT prolonging drug  An H1 receptor antagonist used to prevent itching in allergic conjunctivitis.PubMed search EpinastineDrugBank search Epinastine
Epinephrine (Adrenaline)Primatene, BronkaidClassified as QT prolonging drugCatecholamine, vasoconstrictorAllergic reaction, anaphylaxis, cardiac arrest PubMed search Epinephrine (Adrenaline)DrugBank search Epinephrine (Adrenaline)
EpirubicinEllence, Pharmorubicin, Epirubicin EbeweClassified as QT prolonging drugAnti-cancerCancer PubMed search EpirubicinDrugBank search Epirubicin
Eribulin Classified as QT prolonging drug  A microtubule inhibitor used to treat metastatic breast cancer and metastatic or unresectable liposarcoma.PubMed search EribulinDrugBank search Eribulin
Eribulin mesylateHalavenLow riskAnti-cancerCancer (breast, metastatic) PubMed search Eribulin mesylateDrugBank search Eribulin mesylate
Erlotinib Classified as QT prolonging drug  An EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers.PubMed search ErlotinibDrugBank search Erlotinib
ErythromycinE.E.S., Robimycin, EMycin, Erymax, Ery-Tab, Eryc Ranbaxy, Erypar, Eryped, Erythrocin Stearate Filmtab, Erythrocot, E-Base, Erythroped, Ilosone, MY-E, Pediamycin, Abboticin, Abboticin-ES, Erycin, PCE Dispertab, Stiemycine, Acnasol, TilorythModerate riskAntibioticBacterial infection, increase GI motilityA macrolide antibiotic used to treat and prevent a variety of bacterial infections.PubMed search ErythromycinDrugBank search Erythromycin
EscitalopramCipralex, Lexapro, Nexito, Anxiset-E, Exodus, Esto, Seroplex, Elicea, Lexamil, Lexam, Entact, Losita, Reposil, Animaxen, Esitalo, LexamilModerate riskAntidepressant, SSRIDepression (major), anxiety disordersA selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD).PubMed search EscitalopramDrugBank search Escitalopram
EsomeprazoleNexium, Nexum, InexiumClassified as QT prolonging drugProton Pump InhibitorGastric hyperacidity, GERD PubMed search EsomeprazoleDrugBank search Esomeprazole
EtelcalcetideParsabivModerate riskCalcium sensing receptor agonistSecondary hyperparathyroidism PubMed search EtelcalcetideDrugBank search Etelcalcetide
Ethosuximide Classified as QT prolonging drug  An anticonvulsant used to treat petit mal seizures.PubMed search EthosuximideDrugBank search Ethosuximide
Ezogabine Classified as QT prolonging drug  An antiepileptic agent used as an adjuvant treatment of partial-onset seizures.PubMed search EzogabineDrugBank search Ezogabine
Ezogabine (Retigabine)Potiga, TrobaltLow to moderate riskAnticonvulsantSeizures, Partial PubMed search Ezogabine (Retigabine)DrugBank search Ezogabine (Retigabine)
FamotidinePepcid, Fluxid, QuamatelClassified as QT prolonging drugH2-receptor antagonistGastric hyperacidity, GERDA histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.PubMed search FamotidineDrugBank search Famotidine
Famphur Classified as QT prolonging drug  Not AnnotatedPubMed search FamphurDrugBank search Famphur
Farnesyl diphosphate Classified as QT prolonging drug  Not AvailablePubMed search Farnesyl diphosphateDrugBank search Farnesyl diphosphate
Farnesyl thiopyrophosphate Classified as QT prolonging drug  Not AvailablePubMed search Farnesyl thiopyrophosphateDrugBank search Farnesyl thiopyrophosphate
FelbamateFelbatolClassified as QT prolonging drugAnticonvulsantSeizuresAn anticonvulsant used to treat severe epilepsy.PubMed search FelbamateDrugBank search Felbamate
Fendiline Classified as QT prolonging drug  Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective.PubMed search FendilineDrugBank search Fendiline
FenfluramineFinteplaClassified as QT prolonging druganti convulsantSeizures PubMed search FenfluramineDrugBank search Fenfluramine
FenoterolBerotec, Berodual NClassified as QT prolonging drugbronchodilaterAsthma PubMed search FenoterolDrugBank search Fenoterol
Fenthion Classified as QT prolonging drug  Fenthion is an organothiophosphate drug used as an insecticide, avicide, and acaricide. Its mode of action is explained by cholinesterase enzyme inhibition, which is similar to other organophosphates. Fenthion is…PubMed search FenthionDrugBank search Fenthion
FexinidazoleFexinidazoleModerate riskAntiparasiticAntiparasitic PubMed search FexinidazoleDrugBank search Fexinidazole
FingolimodGilenyaLow to moderate riskSphingosine phospate receptor modulatorMultiple Sclerosis PubMed search FingolimodDrugBank search Fingolimod
FlecainideTambocor, Almarytm, Apocard, Ecrinal, FlécaineClassified as QT prolonging drugAntiarrhythmicArrhythmiaA class Ic antiarrhythmic agent used to manage atrial fibrillation and paroxysmal supraventricular tachycardias (PSVT).PubMed search FlecainideDrugBank search Flecainide
Fleroxacin Classified as QT prolonging drug  Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone.PubMed search FleroxacinDrugBank search Fleroxacin
FloxuridineFloxuridineModerate riskAnti-cancerAnti-cancer PubMed search FloxuridineDrugBank search Floxuridine
FluconazoleDiflucan, TricanModerate riskAntifungalFungal infectionA triazole antifungal used to treat various fungal infections including candidiasis.PubMed search FluconazoleDrugBank search Fluconazole
Flumequine Classified as QT prolonging drug  Flumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections.PubMed search FlumequineDrugBank search Flumequine
Fluorouracil (5-FU)Adrucil, Carac, Efudex, EfudixModerate risk (systemic use)Anti-cancerCancer PubMed search Fluorouracil (5-FU)DrugBank search Fluorouracil (5-FU)
FluoxetineProzac, Sarafem, FontexLow to moderate riskAntidepressant, SSRIDepressionA selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I.PubMed search FluoxetineDrugBank search Fluoxetine
FlupentixolDepixol, FluanxolModerate riskAntipsychoticSchizophreniaA thioxanthene neuroleptic used to treat schizophrenia and depression.PubMed search FlupentixolDrugBank search Flupentixol
Fluspirilene Classified as QT prolonging drug  An antipsychotic agent used in the treatment of schizophrenia.PubMed search FluspirileneDrugBank search Fluspirilene
Fluticasone And SalmeterolAdvair, SeretideLow riskBronchodilatorAsthma PubMed search Fluticasone And SalmeterolDrugBank search Fluticasone And Salmeterol
FluvoxamineFaverin, Fevarin, Floxyfral, Dumyrox, LuvoxClassified as QT prolonging drugSelective Serotonin Reuptake InhibitorDepression, Obsessive Compulsive Disorder PubMed search FluvoxamineDrugBank search Fluvoxamine
FormoterolForadil, Foradile, Oxeze, Oxis, Atock, Atimos, Atimos Modulite, Perforomist, Dulera, Symbicort, Vannair, Quikhale FBLow riskBronchodilatorAsthmaAn inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD.PubMed search FormoterolDrugBank search Formoterol
FoscarnetFoscavirModerate riskAntiviralHIV, CMV, HHVAn antiviral used to treat CMV, HIV, and HSV infections.PubMed search FoscarnetDrugBank search Foscarnet
FostemsavirRukobiaLow to moderate riskAntiviralHIVAn antiretroviral HIV-1 attachment inhibitor targeted against the gp120 subunit within the HIV-1 gp160 envelope glycoprotein.PubMed search FostemsavirDrugBank search Fostemsavir
FurosemideLasix, Fusid, Frumex, LasilixClassified as QT prolonging drugDiureticHypertension, diuresis PubMed search FurosemideDrugBank search Furosemide
Gadobenate (Gadobenic acid)MultihanceModerate riskMRI contrastMRI imaging (liver imaging) PubMed search Gadobenate (Gadobenic acid)DrugBank search Gadobenate (Gadobenic acid)
Gadobenic acid Classified as QT prolonging drug  A gadolinium compound used as a contrast agent in MRIs.PubMed search Gadobenic acidDrugBank search Gadobenic acid
GalantamineReminyl, Nivalin, Razadyne-ER, LycoremineClassified as QT prolonging drugCholinesterase inhibitorDementia (Alzheimer’s Disease)A cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer’s Disease.PubMed search GalantamineDrugBank search Galantamine
Gallopamil Classified as QT prolonging drug  Gallopamil has been used in trials studying the treatment of Asthma.PubMed search GallopamilDrugBank search Gallopamil
GarenoxacinGeninaxClassified as QT prolonging drugAntibioticBacterial infectionInvestigated for use/treatment in bacterial infection.PubMed search GarenoxacinDrugBank search Garenoxacin
GatifloxacinTequinClassified as QT prolonging drugAntibioticBacterial infectionA fourth generation fluoroquinolone used to treat a wide variety of infections in the body.PubMed search GatifloxacinDrugBank search Gatifloxacin
GemifloxacinFactiveModerate riskAntibioticBacterial infectionA quinolone antibacterial agent used for the treatment of acute bacterial exacerbation of chronic bronchitis and mild to moderate community-acquired pneumonia caused by susceptible bacteria.PubMed search GemifloxacinDrugBank search Gemifloxacin
Geranylgeranyl diphosphate Classified as QT prolonging drug  Not AvailablePubMed search Geranylgeranyl diphosphateDrugBank search Geranylgeranyl diphosphate
GilteritinibXospataModerate riskAntineoplasticCancer (Acute Myeloid Leukemia)An AXL receptor tyrosine kinase inhibitor used to treat relapsed or refractory acute myeloid leukemia.PubMed search GilteritinibDrugBank search Gilteritinib
Givinostat Classified as QT prolonging drug  Givinostat has been used in trials studying the treatment of Polycythemia Vera, Juvenile Idiopathic Arthritis, Duchenne Muscular Dystrophy (DMD), Chronic Myeloproliferative Neoplasms, and Polyarticular Course Juvenile Idiopathic Arthritis.PubMed search GivinostatDrugBank search Givinostat
GlasdegibDaurismoLow riskAnti-cancerCancer (Acute myeloid leukemia) PubMed search GlasdegibDrugBank search Glasdegib
Goserelin Classified as QT prolonging drug  A synthetic analog of luteinizing hormone-releasing hormone used to treat breast cancer and prostate cancer by reducing secretion of gonadotropins from the pituitary.PubMed search GoserelinDrugBank search Goserelin
GranisetronKytril, Sancuso, GranisolLow to moderate riskAntiemeticNausea, vomitingA 5HT3 antagonist used to treat nausea and vomiting in cancer therapy and postoperatively.PubMed search GranisetronDrugBank search Granisetron
GrepafloxacinRaxarClassified as QT prolonging drugAntibioticBacterial infectionA fluoroquinolone antibiotic used to treat various gram positive and gram negative bacterial infections.PubMed search GrepafloxacinDrugBank search Grepafloxacin
HalofantrineHalfanModerate riskAntimalarialMalariaAn antimalarial used for the treatment of severe malaria.PubMed search HalofantrineDrugBank search Halofantrine
HaloperidolHaldol, Aloperidin, Bioperidolo, Brotopon, Dozic, Duraperidol, Einalon S, Eukystol, Halosten, Keselan, Linton, Peluces, Serenace, Serenase, SigaperidolHigh risk with IV use. Moderate risk with PO use.AntipsychoticSchizophrenia, agitationAn antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium.PubMed search HaloperidolDrugBank search Haloperidol
Histrelin Classified as QT prolonging drug  A GnRH agonist found in subcutaneous implants used for the treatment of pediatric patients with central precocious puberty and the palliative treatment of advanced prostate cancer.PubMed search HistrelinDrugBank search Histrelin
HydrochlorothiazideApo-Hydro, Aquazide H, BP Zide, Dichlotride, Hydrodiuril, HydroSaluric, Microzide, Esidrex, OreticClassified as QT prolonging drugDiureticHypertension, diuresis PubMed search HydrochlorothiazideDrugBank search Hydrochlorothiazide
Hydrocodone Bitartrate ERHysingla™ ER, Zohydro ERClassified as QT prolonging drugAnalgesicPain, severe PubMed search Hydrocodone Bitartrate ERDrugBank search Hydrocodone Bitartrate ER
Hydroquinidine (Dihydroquinidine)SerecorHigh riskAntiarrhythmicArrhythmia PubMed search Hydroquinidine (Dihydroquinidine)DrugBank search Hydroquinidine (Dihydroquinidine)
HydroxychloroquinePlaquenil, QuineproxLow riskAntimalarial, Anti-inflammatoryMalaria, SLE, rheumatoid arthritisAn antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus.PubMed search HydroxychloroquineDrugBank search Hydroxychloroquine
HydroxyzineAtarax, Vistaril, Aterax, Alamon, Durrax, Equipose, Masmoran, Orgatrax, Paxistil Quiess, Tran-Q, TranquizineLow to moderate riskAntihistamineAnxiety disorders, allergic reactionsAn antihistamine used to treat anxiety and tension associated with psychoneuroses, as well as allergic conditions such as pruritus and chronic urticaria.PubMed search HydroxyzineDrugBank search Hydroxyzine
Hyoscyamine Classified as QT prolonging drug  An anticholinergic indicated to treat functional gastrointestinal disorders, biliary and renal colic, and acute rhinitis.PubMed search HyoscyamineDrugBank search Hyoscyamine
Ibandronate Classified as QT prolonging drug  A bisphosphonate used to treat osteoporosis in postmenopausal women.PubMed search IbandronateDrugBank search Ibandronate
IbogaineIbogaineClassified as QT prolonging drugPsychedelicNarcotic dependence, unproven efficacy PubMed search IbogaineDrugBank search Ibogaine
IbutilideCorvertClassified as QT prolonging drugAntiarrhythmicArrhythmiaA class III antiarrhythmic agent used to correct atrial fibrillation and atrial flutter, which can be considered as an alternative to cardioversion.PubMed search IbutilideDrugBank search Ibutilide
IloperidoneFanapt, Fanapta, ZomarilLow to moderate riskAntipsychotic, atypicalSchizophreniaAn atypical antipsychotic agent used for the acute treatment of schizophrenia in adults.PubMed search IloperidoneDrugBank search Iloperidone
ImatinibGleevec, GlivecClassified as QT prolonging drugAnti-cancerCancer (Acute myeloid leukemia)A tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.PubMed search ImatinibDrugBank search Imatinib
Imipramine Classified as QT prolonging drug  A tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis.PubMed search ImipramineDrugBank search Imipramine
Imipramine (Melipramine)TofranilModerate riskAntidepressant, TricyclicDepression PubMed search Imipramine (Melipramine)DrugBank search Imipramine (Melipramine)
IndacaterolArcapta Neohaler, Onbrez Breezhaler, UtibronLow riskBronchodilatorAsthma, COPDAn inhaled long-acting beta-2 adrenergic agonist used to relax bronchial smooth muscle and improve symptoms and airflow obstruction caused by Chronic Obstructive Pulmonary Disease (COPD) and moderate to severe asthma.PubMed search IndacaterolDrugBank search Indacaterol
IndapamideLozol, Natrilix, InsigClassified as QT prolonging drugDiureticHypertension, diuresisA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure.PubMed search IndapamideDrugBank search Indapamide
Indenolol Classified as QT prolonging drug  Indenolol is a drug of the beta-adrenergic blocker class.PubMed search IndenololDrugBank search Indenolol
Inotersen Classified as QT prolonging drug  An antisense oligonucleotide used to treat polyneuropathy of hereditary transthyretin-mediated amyloidosis.PubMed search InotersenDrugBank search Inotersen
Inotuzumab ozogamicinBesponsaModerate riskAnti-cancerCancer (acute lymphocytic leukemia} PubMed search Inotuzumab ozogamicinDrugBank search Inotuzumab ozogamicin
Isoflurane Classified as QT prolonging drug  An inhaled general anesthetic used in surgery.PubMed search IsofluraneDrugBank search Isoflurane
Isoproterenol (isoprenaline)Medihaler-Iso, IsuprelClassified as QT prolonging drugBronchodilatorAllergic reaction PubMed search Isoproterenol (isoprenaline)DrugBank search Isoproterenol (isoprenaline)
IsradipineDynacircClassified as QT prolonging drugAntihypertensiveHypertensionA dihydropyridine calcium channel blocker used for the treatment of hypertension.PubMed search IsradipineDrugBank search Isradipine
ItraconazoleSporanox, OnmelLow to moderate riskAntifungalFungal infectionAn antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis.PubMed search ItraconazoleDrugBank search Itraconazole
IvabradineProcoralan, Coralan, Corlentor, Coraxan, Ivabid, BradiaClassified as QT prolonging drugAntianginalAngina Pectoris (heart pain) PubMed search IvabradineDrugBank search Ivabradine
IvosidenibTibsovoHigh riskIDH1 inhibitorCancer (Acute myeloid leukemia)An isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia and cholangiocarcinoma in adults with a susceptible IDH1 mutation.PubMed search IvosidenibDrugBank search Ivosidenib
KetanserinSufrexalClassified as QT prolonging drugAntihypertensiveHypertension PubMed search KetanserinDrugBank search Ketanserin
KetoconazoleNizoral, Sebizole, Ketomed, KetonLow to moderate riskAntifungalFungal infectionA broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.PubMed search KetoconazoleDrugBank search Ketoconazole
LacidipineLacidipineClassified as QT prolonging drug   PubMed search LacidipineDrugBank search Lacidipine
LansoprazolePrevacid, OgastClassified as QT prolonging drugProton Pump InhibitorGastric hyperacidity, GERD PubMed search LansoprazoleDrugBank search Lansoprazole
LapatinibTykerb, TyverbLow riskAnti-cancerCancer (breast, metastatic)An antineoplastic agent and tyrosine kinase inhibitor used for the treatment of advanced or metastatic HER-negative breast cancer in patients who received prior chemotherapeutic treatments.PubMed search LapatinibDrugBank search Lapatinib
LefamulinXenletaClassified as QT prolonging drugAntibioticCommunity acquired pneumonia PubMed search LefamulinDrugBank search Lefamulin
LenvatinibLenvimaHigh riskAnti-cancerCancer (Thyroid)A receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma.PubMed search LenvatinibDrugBank search Lenvatinib
Leuprolide Classified as QT prolonging drug  A peptide-based GnRH receptor superagonist used for the palliative treatment of prostate cancer, uterine leiomyomata, endometriosis, and central precocious puberty.PubMed search LeuprolideDrugBank search Leuprolide
Leuprolide / LeuprorelinLupron, Eligard, Viadur, Carcinil, Enanton, Leuplin, Lucrin, Procren, ProstapClassified as QT prolonging drugAnti-androgenCancer (prostate) PubMed search Leuprolide / LeuprorelinDrugBank search Leuprolide / Leuprorelin
Levacetylmethadol Classified as QT prolonging drug  For the treatment and management of opiate dependence. It is sometimes used to treat severe pain in terminal patients.PubMed search LevacetylmethadolDrugBank search Levacetylmethadol
Levalbuterol (Levsalbutamol)Xopenex, Levolin, AxazestLow riskBronchodilatorAsthma PubMed search Levalbuterol (Levsalbutamol)DrugBank search Levalbuterol (Levsalbutamol)
LevetiracetamKeppraClassified as QT prolonging drugAnti-seizureEpilepsy PubMed search LevetiracetamDrugBank search Levetiracetam
Levocetirizine Classified as QT prolonging drug  An H1-receptor antagonist used to treat symptoms associated with chronic allergic rhinitis and uncomplicated cases of chronic idiopathic urticaria.PubMed search LevocetirizineDrugBank search Levocetirizine
LevofloxacinLevaquin, TavanicModerate riskAntibioticBacterial infectionA fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague.PubMed search LevofloxacinDrugBank search Levofloxacin
LevoketoconazoleRecorlevHigh riskCYP450 inhibitorCushing’s diseaseOne of two enantiomeric forms of racemic ketoconazole that strongly inhibits multiple steroidogenic enzymes and is used for the symptomatic treatment of endogenous Cushing’s syndrome.PubMed search LevoketoconazoleDrugBank search Levoketoconazole
Levomenthol Classified as QT prolonging drug  An organic compound used to treat mild to moderate muscle and joint pain.PubMed search LevomentholDrugBank search Levomenthol
Levomepromazine (Methotrimeprazine)Nosinan, Nozinan, LevopromeClassified as QT prolonging drugAntipsychoticSchizophrenia PubMed search Levomepromazine (Methotrimeprazine)DrugBank search Levomepromazine (Methotrimeprazine)
LevomethadoneLevomethadoneClassified as QT prolonging drugOpioidOpiate withdrawal syndrome PubMed search LevomethadoneDrugBank search Levomethadone
Levomethadyl acetateOrlaamClassified as QT prolonging drugOpioid agonistNarcotic dependence PubMed search Levomethadyl acetateDrugBank search Levomethadyl acetate
Levomethamphetamine (Levmetamfetamine)Sinu Inhaler, Vapor InhalerClassified as QT prolonging drugSympathomimeticSinus Congestion PubMed search Levomethamphetamine (Levmetamfetamine)
LevosulpirideLesuride, Levazeo, EnlivaClassified as QT prolonging drugAntipsychoticSchizophrenia PubMed search LevosulpirideDrugBank search Levosulpiride
Lidoflazine Classified as QT prolonging drug  Not AnnotatedPubMed search LidoflazineDrugBank search Lidoflazine
LisdexamfetamineVyvanseClassified as QT prolonging drugCNS stimulantADHD PubMed search LisdexamfetamineDrugBank search Lisdexamfetamine
LithiumEskalith, LithobidClassified as QT prolonging drugAntimanicBipolar disorder PubMed search LithiumDrugBank search Lithium
Lithium cation Classified as QT prolonging drug  A drug used for the management of bipolar disorder and other psychiatric conditions.PubMed search Lithium cationDrugBank search Lithium cation
Lithium citrate Classified as QT prolonging drug  Lithium is used as a mood stabilizer, and is used for treatment of depression and mania. It is often used in bipolar disorder treatment.PubMed search Lithium citrateDrugBank search Lithium citrate
LofexidineLucemyraModerate riskAlpha-2-adrenergic agonist, centralOpioid withdrawal syndrome PubMed search LofexidineDrugBank search Lofexidine
Lomefloxacin Classified as QT prolonging drug  A fluoroquinolone used to prevent and treat a wide variety of infections in the body.PubMed search LomefloxacinDrugBank search Lomefloxacin
LoperamideImodiumRisk if overdosedOpioid agonistDiarrhea PubMed search LoperamideDrugBank search Loperamide
Lopinavir Classified as QT prolonging drug  An HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection.PubMed search LopinavirDrugBank search Lopinavir
Lopinavir/RitonavirKaletra, AluviaLow to moderate riskAntiviralHIV/AIDS PubMed search Lopinavir/RitonavirDrugBank search Lopinavir/Ritonavir
Lorajmine Classified as QT prolonging drug  Not AnnotatedPubMed search LorajmineDrugBank search Lorajmine
Lorcainide Classified as QT prolonging drug  Not AnnotatedPubMed search LorcainideDrugBank search Lorcainide
Losartan Classified as QT prolonging drug  An angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke.PubMed search LosartanDrugBank search Losartan
LumateperoneCaplytaClassified as QT prolonging drugAntipsychotic, atypicalSchizophrenia PubMed search LumateperoneDrugBank search Lumateperone
Lumefantrine Classified as QT prolonging drug  An antimalarial agent used in combination with artemether for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum.PubMed search LumefantrineDrugBank search Lumefantrine
LurasidoneLatudaClassified as QT prolonging drugAntipsychotic, atypicalSchizophrenia, biopolar disorder and othersAn atypical antipsychotic used to treat schizophrenia and depressive episodes associated with bipolar I disorder.PubMed search LurasidoneDrugBank search Lurasidone
MaprotilineLudiomilClassified as QT prolonging drugAnti-depressant, TetracyclicDepressionA tetracyclic antidepressant used to treat depressive illness, major depressive disorder, bipolar disorder, and anxiety associated with depression.PubMed search MaprotilineDrugBank search Maprotiline
Mefloquine Classified as QT prolonging drug  An antimalarial agent used in the prophylaxis and treatment of malaria caused by Plasmodium falciparum and Plasmodium vivax.PubMed search MefloquineDrugBank search Mefloquine
Meglumine antimoniateGlucantimeModerate riskAntiparasiticLeishmaniasis PubMed search Meglumine antimoniateDrugBank search Meglumine antimoniate
MelperoneBunil, Buronil, EunerpanClassified as QT prolonging drugAntipsychotic, atypicalSchizophreniaAn atypical butyrophenone antipsychotic used to treat sleep disorders, confusion, and psychomotor dysfunction associated with geriatric, psychiatric, and alcohol-dependent patients.PubMed search MelperoneDrugBank search Melperone
Mepyramine Classified as QT prolonging drug  An antihistamine agent used for the symptomatic treatment of allergy, hypersensitivity reactions, and pruritic skin disorders.PubMed search MepyramineDrugBank search Mepyramine
Mequitazine Classified as QT prolonging drug  For the treatment of Hay fever, urticaria (hives) and allergic rhinitisPubMed search MequitazineDrugBank search Mequitazine
MesoridazineSerentilClassified as QT prolonging drugAntipsychoticSchizophreniaA phenothiazine antipsychotic used to treat schizophrenia, organic brain disorders, alcoholism, and psychoneuroses.PubMed search MesoridazineDrugBank search Mesoridazine
Metaproterenol (Orciprenaline)Metaprel, AlupentClassified as QT prolonging drugBronchodilatorAsthma PubMed search Metaproterenol (Orciprenaline)DrugBank search Metaproterenol (Orciprenaline)
MethadoneDolophine, Symoron, Amidone, Methadose, Physeptone, HeptadonHigh riskOpioid agonistNarcotic dependence, painAn opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction.PubMed search MethadoneDrugBank search Methadone
Methamphetamine (Metamfetamine)Desoxyn, Pervitin, Anadrex, Methedrine, SyndroxClassified as QT prolonging drugCNS stimulantObesity, ADHD PubMed search Methamphetamine (Metamfetamine)DrugBank search Methamphetamine (Metamfetamine)
Methotrimeprazine Classified as QT prolonging drug  A phenothiazine used in the management of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder.PubMed search MethotrimeprazineDrugBank search Methotrimeprazine
MethylphenidateRitalin, Concerta, Focalin, Daytrana, Methylin, Metadate CDClassified as QT prolonging drugCNS stimulantADHD PubMed search MethylphenidateDrugBank search Methylphenidate
MetoclopramideReglan, Gimoti, Afipran, Maxolon, Cerucal, Clopamon, Clopra, Maxeran, Maxolon, Metozolv, Plasil, Pramin, Primperan, PerinormLow to moderate riskAntiemeticNausea, vomitingAn antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.PubMed search MetoclopramideDrugBank search Metoclopramide
MetolazoneZytanix, Zaroxolyn, MykroxClassified as QT prolonging drugDiureticHypertension, diuresis PubMed search MetolazoneDrugBank search Metolazone
MetronidazoleFlagyl, HelidacLow to moderate riskAntibioticTrichomoniasis, amebiasis, bacterial infectionA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.PubMed search MetronidazoleDrugBank search Metronidazole
MianserinTolvonClassified as QT prolonging drugAnti-depressantDepression PubMed search MianserinDrugBank search Mianserin
Mibefradil Classified as QT prolonging drug  For the treatment of angina and high blood pressure.PubMed search MibefradilDrugBank search Mibefradil
MidodrineProAmatine, Amatine, GutronClassified as QT prolonging drugVasoconstrictorHypotension PubMed search MidodrineDrugBank search Midodrine
MidostaurinRydaptModerate riskAnti-cancerCancer (Acute myeloid leukemia) PubMed search MidostaurinDrugBank search Midostaurin
MifepristoneKorlym, MifeprexLow to moderate riskProgesterone antagonistPregnancy terminationA cortisol receptor blocker used to treat Cushing’s syndrome, and to terminate pregnancies up to 70 days gestation.PubMed search MifepristoneDrugBank search Mifepristone
MirabegronMyrbetriqClassified as QT prolonging drugBeta3 adrenergic antagonistBladder spasmA beta-3 adrenergic agonist used to treat overactive bladder and neurogenic detrusor overactivity.PubMed search MirabegronDrugBank search Mirabegron
MirtazapineRemeronLow riskAntidepressant, TetracyclicDepressionA tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite.PubMed search MirtazapineDrugBank search Mirtazapine
MobocertinibExkivityHigh riskTyrosine kinase inhibitorCancer (Lung)An oral kinase inhibitor targeted against EGFR and used in the treatment of NSCLC with EGFR exon 20 insertion mutations.PubMed search MobocertinibDrugBank search Mobocertinib
Mocetinostat Classified as QT prolonging drug  Mocetinostat has been used in trials studying the treatment of Lymphoma, Urothelial Carcinoma, Relapsed and Refractory, Myelodysplastic Syndrome, and Metastatic Leiomyosarcoma, among others.PubMed search MocetinostatDrugBank search Mocetinostat
Moexipril Classified as QT prolonging drug  An angiotensin converting enzyme inhibitor prodrug used to treat hypertension.PubMed search MoexiprilDrugBank search Moexipril
Moricizine Classified as QT prolonging drug  An antiarrhythmic used to treat arrhythmias.PubMed search MoricizineDrugBank search Moricizine
MoxifloxacinAvelox, Avalox, AvelonModerate riskAntibioticBacterial infectionA fluoroquinolone antibiotic used to treat various bacterial infections.PubMed search MoxifloxacinDrugBank search Moxifloxacin
NecitumumabPortrazzaClassified as QT prolonging druganti-cancerCancer (Lung) PubMed search NecitumumabDrugBank search Necitumumab
NelfinavirViraceptClassified as QT prolonging drugAntiviralViral infection (HIV/AIDS)A viral protease inhibitor used in the treatment of HIV infection.PubMed search NelfinavirDrugBank search Nelfinavir
Nemonoxacin Classified as QT prolonging drug  Investigated for use/treatment in bacterial infection and pneumonia.PubMed search NemonoxacinDrugBank search Nemonoxacin
NicardipineCardeneClassified as QT prolonging drugAntihypertensiveHypertensionA calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina.PubMed search NicardipineDrugBank search Nicardipine
NifekalantShinbitClassified as QT prolonging drugAntiarrhythmicArrhythmia PubMed search NifekalantDrugBank search Nifekalant
Niguldipine Classified as QT prolonging drug  Niguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties.PubMed search NiguldipineDrugBank search Niguldipine
NilotinibTasignaModerate riskAnti-cancerCancer (leukemia)A kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib.PubMed search NilotinibDrugBank search Nilotinib
Nizofenone Classified as QT prolonging drug  Not AnnotatedPubMed search NizofenoneDrugBank search Nizofenone
NorepinephrineLevophedClassified as QT prolonging drugVasconstrictor, InotropeHeart failure, shock (low blood pressure) PubMed search NorepinephrineDrugBank search Norepinephrine
NorfloxacinNoroxin, AmbigramLow to moderate riskAntibioticBacterial infectionA broad-spectrum fluoroquinolone antibiotic with variable activity against gram-positive and gram-negative bacteria. Typically reserved for the treatment of UTIs due to accumulation in the urine.PubMed search NorfloxacinDrugBank search Norfloxacin
NortriptylinePamelor, Sensoval, Aventyl, Norpress, Allegron, Noritren, NortrilenClassified as QT prolonging drugAntidepressant, TricyclicDepressionA tricyclic antidepressant used in the treatment of depression.PubMed search NortriptylineDrugBank search Nortriptyline
NusinersenSpinrazaClassified as QT prolonging drugAntisense oligonucleotideSpinal Muscular Atrophy PubMed search NusinersenDrugBank search Nusinersen
Octreotide Classified as QT prolonging drug  A peptide drug used to treat acromegaly as well as diarrhea associated with metastatic carcinoid tumors and vasoactive intestinal peptide secreting tumors.PubMed search OctreotideDrugBank search Octreotide
OfloxacinFloxinLow to moderate riskAntibioticBacterial infectionAn antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract.PubMed search OfloxacinDrugBank search Ofloxacin
OlanzapineZyprexa, Zydis, RelprevvModerate riskAntipsychotic, atypicalSchizophrenia, bipolar disorderAn antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders.PubMed search OlanzapineDrugBank search Olanzapine
OliceridineOlinvykClassified as QT prolonging druganalgesiapain PubMed search OliceridineDrugBank search Oliceridine
OlodaterolStriverdi RespimatLow riskBronchodilatorAsthmaA long-acting beta2-adrenergic agonist used in the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.PubMed search OlodaterolDrugBank search Olodaterol
OmeprazoleLosec, Prilosec, Zegerid, MopralClassified as QT prolonging drugProton Pump InhibitorGastric hyperacidity, GERD PubMed search OmeprazoleDrugBank search Omeprazole
OndansetronZofran, Anset, Ondemet, Zuplenz, Emetron, Ondavell, Emeset, Ondisolv, SetronaxModerate risk with IV use. Low risk with PO use.AntiemeticNausea, vomitingA serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting in cancer chemotherapy and postoperatively.PubMed search OndansetronDrugBank search Ondansetron
Orbifloxacin Classified as QT prolonging drug  Orbifloxacin is a fluoroquinolone antibiotic. It is marketed by Schering-Plough Animal Health and approved for certain infections in dogs.PubMed search OrbifloxacinDrugBank search Orbifloxacin
OsilodrostatIsturisaClassified as QT prolonging drugAldosterone synthase inhibitorCushing’s Disease PubMed search OsilodrostatDrugBank search Osilodrostat
OsimertinibTagrissoModerate riskAnti-cancerCancer (EGFR pos. NSC Lung cancer) PubMed search OsimertinibDrugBank search Osimertinib
OxaliplatinEloxatinLow riskAnti-cancerCancerA platinum based chemotherapy agent used to treat carcinoma of the colon or rectum or stage III colon cancer.PubMed search OxaliplatinDrugBank search Oxaliplatin
Oxatomide Classified as QT prolonging drug  An antihistamine indicated in the treatment and prevention of allergic symptoms.PubMed search OxatomideDrugBank search Oxatomide
Oxolinic acid Classified as QT prolonging drug  Not AnnotatedPubMed search Oxolinic acidDrugBank search Oxolinic acid
OxymetazolineAfrin, Otrivin, Vicks Sinex, ZicamClassified as QT prolonging drugDecongestantAllergic rhinitis PubMed search OxymetazolineDrugBank search Oxymetazoline
OxytocinPitocin, SyntocinonModerate riskOxytocicLabor stimulationA recombinant hormone used to induce or strengthen uterine contractions in pregnant women to aid in labor and delivery or to control postpartum bleeding.PubMed search OxytocinDrugBank search Oxytocin
OzanimodZeposiaLow to moderate riskImmunomodulationMultiple Sclerosis PubMed search OzanimodDrugBank search Ozanimod
PacritinibVonjoLow riskKinase (JAK2) inhibitorMyelofibrosis PubMed search PacritinibDrugBank search Pacritinib
PaliperidoneInvega, XepilonLow to moderate riskAntipsychotic, atypicalSchizophreniaAn atypical antipsychotic used in the treatment of schizophrenia and other schizoaffective or delusional disorders.PubMed search PaliperidoneDrugBank search Paliperidone
PalonosetronAloxiClassified as QT prolonging drugAntiemeticNausea, vomiting PubMed search PalonosetronDrugBank search Palonosetron
PanobinostatFarydakLow riskHistone deacetylase inhibitorCancer, Multiple myelomaA non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents.PubMed search PanobinostatDrugBank search Panobinostat
PantoprazoleProtonix, Inipomp, EupantolClassified as QT prolonging drugProton Pump InhibitorGastric hyperacidity, GERD PubMed search PantoprazoleDrugBank search Pantoprazole
PapaverinePapaverineHigh risk (intracoronary administration)Vasodilator, CoronaryDiagnostic adjunctAn alkaloid used to treat many types of smooth muscle spasms such as “vascular spasms” associated with acute myocardial infarction and angina pectoris, as well as “visceral spasms”.PubMed search PapaverineDrugBank search Papaverine
ParoxetinePaxil, Aropax, Pexeva, Seroxat, Sereupin, Seroxat, DeroxatClassified as QT prolonging drugAntidepressant, SSRIDepression PubMed search ParoxetineDrugBank search Paroxetine
PasireotideSigniforLow to moderate riskSomatostatin analogCushing’s DiseaseA somatostatin analog used in the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery is not appropriate.PubMed search PasireotideDrugBank search Pasireotide
PazopanibVotrientModerate riskAnti-cancerCancer (renal cell, sarcoma)An antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy.PubMed search PazopanibDrugBank search Pazopanib
Pazufloxacin Classified as QT prolonging drug  Pazufloxacin is under investigation in clinical trial NCT02592096 (Pazufloxacin Mesilate Ear Drops Clinical Trial Protocol).PubMed search PazufloxacinDrugBank search Pazufloxacin
Pefloxacin Classified as QT prolonging drug  An antibiotic used to treat a variety of bacterial infections.PubMed search PefloxacinDrugBank search Pefloxacin
Penfluridol Classified as QT prolonging drug  Not AnnotatedPubMed search PenfluridolDrugBank search Penfluridol
PentamidinePentamModerate riskAntifungalFungal infection (Pneumocystis pneumonia)An antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV.PubMed search PentamidineDrugBank search Pentamidine
Perflutren Classified as QT prolonging drug  A diagnostic medication to improve contrast during echocardiograms.PubMed search PerflutrenDrugBank search Perflutren
Perflutren lipid microspheresDefinity, OptisonClassified as QT prolonging drugImaging contrast agentDiagnostic adjunct PubMed search Perflutren lipid microspheresDrugBank search Perflutren lipid microspheres
Perhexiline Classified as QT prolonging drug  For the management of severe angina pectoris.PubMed search PerhexilineDrugBank search Perhexiline
PericiazinePericiazineLow to moderate riskAntipsychotic, atypicalSchizophrenia PubMed search PericiazineDrugBank search Periciazine
PerphenazineTrilafon, Etrafon/Triavil, DecentanClassified as QT prolonging drugAntipsychoticSchizophrenia PubMed search PerphenazineDrugBank search Perphenazine
PhendimetrazineBontril, Adipost, Anorex, Plegine, Appecon, Melfiat, Obezine, Phendiet, Prelu-2, StatobexClassified as QT prolonging drug Obesity PubMed search PhendimetrazineDrugBank search Phendimetrazine
Pheniramine Classified as QT prolonging drug  An antihistamine used to treat allergic rhinitis and pruritus.PubMed search PheniramineDrugBank search Pheniramine
PhentermineAdipex P, Adiphene, Anoxine-AM, Ionamin, Duromine, Metermine, Miraprontv, Obephen, Obermine, Obestin-30, Phentremine, Phentrol, Phenterex, Phentromin, Pro-Fast SA, Redusa, Panbesy, Obenix, Oby-Trim, Teramine, Zantryl, Sinpet, Supremin, Suprenza, Umine, WeltmineClassified as QT prolonging drugAppetite suppressantObesity PubMed search PhentermineDrugBank search Phentermine
PhenylephrineNeosynephrineClassified as QT prolonging drugVasoconstrictorShock (low blood pressure), allergic rhinitis, asthma PubMed search PhenylephrineDrugBank search Phenylephrine
PhenylpropanolamineAcutrim, DexatrimClassified as QT prolonging drugAppetite suppressantObesity PubMed search PhenylpropanolamineDrugBank search Phenylpropanolamine
Phosmet Classified as QT prolonging drug  Phosmet is a phthalimide-derived organophosphate. It is a non-specific insecticide. It is mainly used on apple trees to control codling moths. It is also used on other fruit crops, ornamentals,…PubMed search PhosmetDrugBank search Phosmet
PilsicainideSunrythmClassified as QT prolonging drugAnti-arrhythmicArrhythmiaPilsicainide has been investigated for the treatment of Paroxysmal Atrial Fibrillation.PubMed search PilsicainideDrugBank search Pilsicainide
PimavanserinNuplazidLow to moderate riskAntipsychotic, atypicalPsychosis, Parkinson’s Disease PubMed search PimavanserinDrugBank search Pimavanserin
PimozideOrapModerate riskAntipsychoticPsychosis, Tourette’s DisorderAn antipsychotic used to manage debilitating motor and phonic tics in patients with Tourette’s Disorder.PubMed search PimozideDrugBank search Pimozide
PipamperoneDipiperon, Propitan, Dipiperal, Piperonil, PiperonylClassified as QT prolonging drugAntipsychoticSchizophrenia PubMed search PipamperoneDrugBank search Pipamperone
Piperacillin / TazobactamTazosyn, Zosyn, PipTazClassified as QT prolonging drugAntibioticBacterial infection PubMed search Piperacillin / TazobactamDrugBank search Piperacillin / Tazobactam
Piromidic acid Classified as QT prolonging drug  Not AnnotatedPubMed search Piromidic acidDrugBank search Piromidic acid
Pitolisant Classified as QT prolonging drug  An antagonist and inverse agonist at the histamine H3 receptor that is used to treat narcolepsy in adults.PubMed search PitolisantDrugBank search Pitolisant
Pitolisant (Tiprolisant)WakixClassified as QT prolonging drugHistamine 3 antagonist/inverse agonistNarcolepsy PubMed search Pitolisant (Tiprolisant)DrugBank search Pitolisant (Tiprolisant)
PonesimodPonvoryLow to moderate riskSphingosine 1-phosphate receptor modulatorMultiple Sclerosis PubMed search PonesimodDrugBank search Ponesimod
PosaconazoleNoxafil, PosamolClassified as QT prolonging drugAntifungalFungal infectionA triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.PubMed search PosaconazoleDrugBank search Posaconazole
Pracinostat Classified as QT prolonging drug  For the treatment of various forms of cancer.PubMed search PracinostatDrugBank search Pracinostat
Prajmaline Classified as QT prolonging drug  Not AnnotatedPubMed search PrajmalineDrugBank search Prajmaline
Pregabalin Classified as QT prolonging drug  An anticonvulsant drug used to treat neuropathic pain conditions and fibromyalgia, and for the treatment of partial onset seizures in combination with other anticonvulsants.PubMed search PregabalinDrugBank search Pregabalin
Prenylamine Classified as QT prolonging drug  Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.PubMed search PrenylamineDrugBank search Prenylamine
PretomanidPretomanidClassified as QT prolonging drugAntitubercularTuberculosis, extensively drug resistant PubMed search PretomanidDrugBank search Pretomanid
Primaquine Classified as QT prolonging drug  An antimalarial indicated to prevent relapse of vivax malaria.PubMed search PrimaquineDrugBank search Primaquine
Primaquine phosphateNeo-Quipenyl, PrimachinClassified as QT prolonging drugAntimalarialMalaria PubMed search Primaquine phosphateDrugBank search Primaquine phosphate
ProbucolLorelcoModerate riskAntilipemicHypercholesterolemiaUsed to lower LDL and HDL cholesterol.PubMed search ProbucolDrugBank search Probucol
ProcainamidePronestyl, ProcanClassified as QT prolonging drugAntiarrhythmicArrhythmiaA medication used to treat life threatening ventricular arrhythmias.PubMed search ProcainamideDrugBank search Procainamide
Promazine Classified as QT prolonging drug  A phenothiazine used to manage schizophrenia.PubMed search PromazineDrugBank search Promazine
PromethazinePhenerganClassified as QT prolonging drugAntipsychotic / AntiemeticNausea, vomitingA first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness.PubMed search PromethazineDrugBank search Promethazine
PropafenoneRythmol SR, RytmonormClassified as QT prolonging drugSodium channel blockerArrhythmiaA Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias.PubMed search PropafenoneDrugBank search Propafenone
PropofolDiprivan, PropovenModerate riskAnesthetic, generalAnesthesiaA medication used in general anesthesia and for sedation.PubMed search PropofolDrugBank search Propofol
ProthipendylDominal, Largophren, Timoval, Timovan, TumovanClassified as QT prolonging drugAntipsychoticSchizophrenia PubMed search ProthipendylDrugBank search Prothipendyl
Protriptyline Classified as QT prolonging drug  A tricyclic antidepressant that is indicated in the treatment of depression only under close clinical supervision.PubMed search ProtriptylineDrugBank search Protriptyline
PseudoephedrinePediaCare, SudafedClassified as QT prolonging drugDecongestantAllergic reaction, allergic rhinitis, asthma PubMed search PseudoephedrineDrugBank search Pseudoephedrine
QuetiapineSeroquelModerate riskAntipsychotic, atypicalSchizophreniaA psychotropic agent used for the management of bipolar disorder, schizophrenia, and major depressive disorder.PubMed search QuetiapineDrugBank search Quetiapine
QuinidineQuinaglute, Duraquin, Quinact, Quinidex, Cin-Quin, QuinoraHigh riskAntiarrhythmicArrhythmiaA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.PubMed search QuinidineDrugBank search Quinidine
Quinine Classified as QT prolonging drug  An alkaloid used to treat uncomplicated Plasmodium falciparum malaria.PubMed search QuinineDrugBank search Quinine
Quinine sulfateQualaquin, HexaquineHigh riskAntimalarialMalaria, leg cramps PubMed search Quinine sulfateDrugBank search Quinine sulfate
RanolazineRanexa, RanozexLow riskAntianginalAngina Pectoris (heart pain)An anti-anginal drug used for the treatment of chronic angina.PubMed search RanolazineDrugBank search Ranolazine
RelugolixOrgovyx, ReluminaClassified as QT prolonging drugGnRH antagonistCancer (prostate)An oral GnRH receptor antagonist for androgen deprivation therapy in the treatment of advanced prostate cancer.PubMed search RelugolixDrugBank search Relugolix
RemimazolamByfavoClassified as QT prolonging drugSedativeSedation PubMed search RemimazolamDrugBank search Remimazolam
RibociclibKisqaliModerate riskAnti-cancerCancer (breast) PubMed search RibociclibDrugBank search Ribociclib
Ricolinostat Classified as QT prolonging drug  Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer.PubMed search RicolinostatDrugBank search Ricolinostat
RilpivirineEdurant, Complera, Eviplera, JulucaLow to moderate riskAntiviralViral infection (HIV/AIDS)A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1).PubMed search RilpivirineDrugBank search Rilpivirine
RisperidoneRisperdalModerate riskAntipsychotic, atypicalSchizophreniaA second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression.PubMed search RisperidoneDrugBank search Risperidone
RitodrineYutoparClassified as QT prolonging drugMuscle relaxantPremature labor PubMed search RitodrineDrugBank search Ritodrine
Ritonavir Classified as QT prolonging drug  An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.PubMed search RitonavirDrugBank search Ritonavir
RomidepsinIstodaxLow riskHistone deacetylase inhibitorCancer (lymphoma)A histone deacetylase (HDAC) inhibitor used to treat cutaneous T-cell lymphoma.PubMed search RomidepsinDrugBank search Romidepsin
Rosoxacin Classified as QT prolonging drug  For the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients.PubMed search RosoxacinDrugBank search Rosoxacin
RoxithromycinRulide, Xthrocin, Roxl-150, Roxo, Surlid, Rulide, Biaxsig, Roxar, Roximycinv, Roxomycin, Rulid, Tirabicin, CoroxinLow to moderate riskAntibioticBacterial infectionAn antibiotic used to treat a variety of susceptible bacterial infections.PubMed search RoxithromycinDrugBank search Roxithromycin
RucaparibRubracaClassified as QT prolonging drugPARP inhibitorCancer PubMed search RucaparibDrugBank search Rucaparib
Salbutamol Classified as QT prolonging drug  A beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms.PubMed search SalbutamolDrugBank search Salbutamol
SalmeterolSerevent, AdvairLow riskBronchodilatorAsthmaA long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD.PubMed search SalmeterolDrugBank search Salmeterol
SaquinavirInviraseModerate riskAntiviralViral infection (HIV/AIDS)An HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency.PubMed search SaquinavirDrugBank search Saquinavir
Sarafloxacin Classified as QT prolonging drug  Sarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada.PubMed search SarafloxacinDrugBank search Sarafloxacin
SelpercatinibRetevmoHigh riskKinase inhibitorLung cancer PubMed search SelpercatinibDrugBank search Selpercatinib
SertindoleSerdolect, SerlectHigh riskAntipsychotic, atypicalSchizophrenia, anxietyAn atypical antipsychotic indicated in the treatment of schizophrenia.PubMed search SertindoleDrugBank search Sertindole
SertralineZoloft, LustralLow to moderate riskAntidepressant, SSRIDepression PubMed search SertralineDrugBank search Sertraline
SevofluraneUltane, SojournClassified as QT prolonging drugAnesthetic, generalAnesthesiaA inhalation anaesthetic agent used for induction and maintenance of general anesthesia during surgical procedures.PubMed search SevofluraneDrugBank search Sevoflurane
SibutramineMeridiaClassified as QT prolonging drugAppetite suppressantObesity PubMed search SibutramineDrugBank search Sibutramine
Simendan Classified as QT prolonging drug  Simendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure).PubMed search SimendanDrugBank search Simendan
SiponimodMayzentClassified as QT prolonging drug Multiple Sclerosis PubMed search SiponimodDrugBank search Siponimod
SolifenacinVesicareClassified as QT prolonging drugMuscle relaxantBladder spasmA muscarinic antagonist with antispasmodic properties used to treat urge urinary incontinence, urgency, and urinary frequency associated with an overactive bladder.PubMed search SolifenacinDrugBank search Solifenacin
SorafenibNexavarLow riskAnti-cancerCancer (liver, renal cell, metastatic thyroid)A kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma.PubMed search SorafenibDrugBank search Sorafenib
SotalolBetapace, Sotalex, Sotacor, Sotalol-AFClassified as QT prolonging drugAntiarrhythmicArrhythmiaA methane sulfonanilide beta adrenergic antagonist used to treat life-threatening ventricular arrhythmias and to maintain sinus rhythm in atrial fibrillation or flutter.PubMed search SotalolDrugBank search Sotalol
SparfloxacinZagamModerate riskAntibioticBacterial infectionA fluoroquinolone antibiotic used to treat bacterial respiratory infections and sinusitis.PubMed search SparfloxacinDrugBank search Sparfloxacin
Sulfamethoxazole Classified as QT prolonging drug  An oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract.PubMed search SulfamethoxazoleDrugBank search Sulfamethoxazole
Sulfamethoxazole and TrimethoprimSeptra, Bactrim, Sulfatrim, Biseptol, Co-trimoxazole, Cotrim, Septrin, TrisulClassified as QT prolonging drugAntibioticBacterial infection PubMed search Sulfamethoxazole and TrimethoprimDrugBank search Sulfamethoxazole and Trimethoprim
Sulfisoxazole Classified as QT prolonging drug  A sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections.PubMed search SulfisoxazoleDrugBank search Sulfisoxazole
SulpirideDogmatil, Dolmatil, Eglonyl, Espiride, Modal, SulporClassified as QT prolonging drugAntipsychotic, atypicalSchizophreniaA selective D2 dopamine receptor antagonist indicated to treat chronic and acute schizophrenia.PubMed search SulpirideDrugBank search Sulpiride
SultoprideBarnetil, Barnotil, TopralClassified as QT prolonging drugAntipsychotic, atypicalSchizophreniaSultopride is used in Japan, Hong Kong, and Europe to treat schizophrenia. It is of the drug class atypical antipsychotics .PubMed search SultoprideDrugBank search Sultopride
SunitinibSutentModerate riskAnti-cancerCancer (GIST, renal cell, pNET)A receptor tyrosine kinase inhibitor and chemotherapeutic agent used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).PubMed search SunitinibDrugBank search Sunitinib
TacrolimusPrograf, Prograf, Advagraf, ProtopicClassified as QT prolonging drugImmunosuppressantImmune suppression PubMed search TacrolimusDrugBank search Tacrolimus
Talinolol Classified as QT prolonging drug  Talinolol has been investigated for the basic science of Gastrointestinal Motility Disorder.PubMed search TalinololDrugBank search Talinolol
TamoxifenNolvadex, IstubalLow riskAnti-cancerCancer (breast)A selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women.PubMed search TamoxifenDrugBank search Tamoxifen
Tandutinib Classified as QT prolonging drug  Investigated for use/treatment in leukemia (myeloid).PubMed search TandutinibDrugBank search Tandutinib
TazemetostatTazverikClassified as QT prolonging drugAnti-cancerEpithelioid sarcoma PubMed search TazemetostatDrugBank search Tazemetostat
Technetium Tc-99m ciprofloxacin Classified as QT prolonging drug  Investigated for use/treatment in infectious and parasitic disease (unspecified).PubMed search Technetium Tc-99m ciprofloxacinDrugBank search Technetium Tc-99m ciprofloxacin
Tedisamil Classified as QT prolonging drug  Investigated for use/treatment in arrhythmia, atrial fibrillation, and angina.PubMed search TedisamilDrugBank search Tedisamil
TelaprevirIncivo, IncivekClassified as QT prolonging drugAntiviralViral infection (hepatitis C) PubMed search TelaprevirDrugBank search Telaprevir
TelavancinVibativLow riskAntibioticBacterial infectionAn antibacterial agent used in the treatment of complicated skin and skin structure infections and types of hospital-acquired bacterial pneumonia.PubMed search TelavancinDrugBank search Telavancin
TelithromycinKetekLow to moderate riskAntibioticBacterial infectionAn ketolide used to treat community acquired pneumonia of mild to moderate severity.PubMed search TelithromycinDrugBank search Telithromycin
Temafloxacin Classified as QT prolonging drug  For the treatment of lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections.PubMed search TemafloxacinDrugBank search Temafloxacin
Temefos Classified as QT prolonging drug  Diphos has been used in trials studying the treatment of Plasmodium Falciparum Malaria.PubMed search TemefosDrugBank search Temefos
TerbutalineBrethine, Bricanyl, Brethaire, TerbulinModerate riskBronchodilatorAsthma, premature laborA beta-2 adrenergic agonist used as a bronchodilator and to prevent premature labor.PubMed search TerbutalineDrugBank search Terbutaline
TerfenadineSeldaneClassified as QT prolonging drugAntihistamineAllergic rhinitisAn antihistamine for the treatment of allergy symptoms.PubMed search TerfenadineDrugBank search Terfenadine
TerlipressinTeripress, Glypressin, Terlipin, Remestyp, Tresil, TerissLow to moderate riskVasoconstrictorSeptic shockA drug used to treat bleeding caused by esophageal varices.PubMed search TerlipressinDrugBank search Terlipressin
TerodilineMicturin, MictrolClassified as QT prolonging drugMuscle relaxantBladder spasmNot AnnotatedPubMed search TerodilineDrugBank search Terodiline
TetrabenazineNitoman, XenazineLow to moderate riskVesicular Monoamine Transporter 2 InhibitorChorea (Huntington’s disease)A vesicular monoamine transporter 2 (VMAT) inhibitor used for the management of chorea associated with Huntington’s Disease.PubMed search TetrabenazineDrugBank search Tetrabenazine
Tetrahydropalmatine Classified as QT prolonging drug  Tetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity).PubMed search TetrahydropalmatineDrugBank search Tetrahydropalmatine
ThioridazineMellaril, Novoridazine, ThiorilModerate riskAntipsychoticSchizophreniaA phenothiazine antipsychotic used to treat schizophrenia and generalized anxiety disorder.PubMed search ThioridazineDrugBank search Thioridazine
Thiothixene Classified as QT prolonging drug  An antipsychotic indicated for the management of schizophrenia.PubMed search ThiothixeneDrugBank search Thiothixene
TiaprideTiapridal, Italprid, Sereprile, Tialaread, Tiaryl, Tiaprim, Tiaprizal, Sereprid, TiapridexClassified as QT prolonging drugSelective D2, D3 dopamine antagonistAlcoholism, withdrawal PubMed search TiaprideDrugBank search Tiapride
Tipiracil/TrifluridineLonsurfClassified as QT prolonging drugAnti-cancerCancer (Metastatic colorectal) PubMed search Tipiracil/TrifluridineDrugBank search Tipiracil/Trifluridine
TizanidineZanaflex, SirdaludClassified as QT prolonging drugMuscle relaxantMuscle spasticityAn alpha-2 adrenergic agonist used for the short-term treatment of muscle spasticity.PubMed search TizanidineDrugBank search Tizanidine
TolterodineDetrol, DetrusitolClassified as QT prolonging drugMuscle relaxantBladder spasmA muscarinic receptor antagonist used to treat overactive bladder with urinary incontinence, urgency, and frequency.PubMed search TolterodineDrugBank search Tolterodine
TorasemideDemadex, Diuver, ExamideClassified as QT prolonging drugDiureticHypertension, diuresis PubMed search TorasemideDrugBank search Torasemide
ToremifeneFarestonModerate riskEstrogen agonist/antagonistCancer (breast, metastatic)A first generation nonsteroidal selective estrogen receptor modulator used to treat certain breast cancers.PubMed search ToremifeneDrugBank search Toremifene
TramadolCrispin, Ralivia ER, Ralivia Flashtab, Tramadolum, Tramal, Tramodol, Tridural, Ultram, Ultram ER, Zydol, Ixprim, Zaldiar, TopalgicClassified as QT prolonging drugAnalgesicPain PubMed search TramadolDrugBank search Tramadol
TrazodoneDesyrel, Oleptro, Beneficat, Deprax, Desirel, Molipaxin, Thombran, Trazorel, Trialodine, Trittico, MesyrelLow to moderate riskAntidepressant, SARIDepression, insomniaA serotonin uptake inhibitor used to treat major depressive disorder.PubMed search TrazodoneDrugBank search Trazodone
Treprostinil Classified as QT prolonging drug  A prostacyclin vasodilator for the treatment of pulmonary arterial hypertension to relieve exercise associated symptoms and to prevent clinical deterioration after stopping epoprostenol.PubMed search TreprostinilDrugBank search Treprostinil
Triclabendazole Classified as QT prolonging drug  An anthelmintic drug used to treat fascioliasis.PubMed search TriclabendazoleDrugBank search Triclabendazole
Trimethadione Classified as QT prolonging drug  An anticonvulsant agent indicated for the control of treatment-refractory petit mal seizures.PubMed search TrimethadioneDrugBank search Trimethadione
TrimipramineSurmontil, Rhotrimine, StangylClassified as QT prolonging drugAntidepressant, TricyclicDepressionA tricyclic antidepressant used to treat depression.PubMed search TrimipramineDrugBank search Trimipramine
Triptorelin Classified as QT prolonging drug  A GnRH agonist indicated for the palliative treatment of advanced prostate cancer.PubMed search TriptorelinDrugBank search Triptorelin
TropisetronNavoban, SetrovelLow to moderate riskAntiemeticNausea, vomiting PubMed search TropisetronDrugBank search Tropisetron
Trovafloxacin Classified as QT prolonging drug  An antibiotic used to treat gonorrhea and chlamydia.PubMed search TrovafloxacinDrugBank search Trovafloxacin
Tucidinostat Classified as QT prolonging drug  Investigated for use/treatment in cancer/tumors (unspecified).PubMed search TucidinostatDrugBank search Tucidinostat
ValbenazineIngrezzaClassified as QT prolonging drugVesicular monamine transporter 2 inhibitorTardive Dyskinesia PubMed search ValbenazineDrugBank search Valbenazine
Valproic acid Classified as QT prolonging drug  An anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.PubMed search Valproic acidDrugBank search Valproic acid
VandetanibCaprelsaHigh riskAnti-cancerCancer (thyroid)An antineoplastic kinase inhibitor used to treat symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease.PubMed search VandetanibDrugBank search Vandetanib
VardenafilLevitraClassified as QT prolonging drugPhosphodiesterase 5 inhibitorErectile dysfunctionA phosphodiesterase 5 inhibitor used to treat erectile dysfunction.PubMed search VardenafilDrugBank search Vardenafil
VemurafenibZelborafModerate riskAnti-cancerCancer (melanoma)A kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation.PubMed search VemurafenibDrugBank search Vemurafenib
VenlafaxineEffexor, EfexorClassified as QT prolonging drugAntidepressant, SNRIDepressionA selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression, generalized or social anxiety disorder, and panic disorder.PubMed search VenlafaxineDrugBank search Venlafaxine
VernakalantBrinavessHigh riskAntiarrhythmic drugAtrial fibrillationAn antiarrhythmic medication used to treat patients with atrial fibrillation.PubMed search VernakalantDrugBank search Vernakalant
Vilanterol Classified as QT prolonging drug  A long-acting beta2-adrenergic agonist used in combination with other bronchodilators for the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.PubMed search VilanterolDrugBank search Vilanterol
Vilanterol/fluticasone furoateBreo ElliptaLow riskBronchodilatorAsthma PubMed search Vilanterol/fluticasone furoateDrugBank search Vilanterol/fluticasone furoate
VoclosporinLupkynisLow to moderate riskImmunosupressantLupus nephritis PubMed search VoclosporinDrugBank search Voclosporin
VoriconazoleVFendModerate riskAntifungalFungal infectionA triazole compound used to treat fungal infections.PubMed search VoriconazoleDrugBank search Voriconazole
VorinostatZolinzaLow riskHistone deacetylase inhibitorCancer (lymphoma)A histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies.PubMed search VorinostatDrugBank search Vorinostat
Xylometazoline (Xylomethazoline)Sinosil, Aqua MarisClassified as QT prolonging drugSympathomimeticNasal Congestion PubMed search Xylometazoline (Xylomethazoline)DrugBank search Xylometazoline (Xylomethazoline)
ZiprasidoneGeodon, ZeldoxHigh riskAntipsychotic, atypicalSchizophreniaAn atypical antipsychotic used to manage schizophrenia, bipolar mania, and agitation in patients with schizophrenia.PubMed search ZiprasidoneDrugBank search Ziprasidone
ZotepineLosizopilon, Lodopin, Setous, ZoleptilClassified as QT prolonging drugAntipsychotic, atypicalSchizophrenia PubMed search ZotepineDrugBank search Zotepine
Zuclopenthixol Classified as QT prolonging drug  An antipsychotic indicated for the management of schizophrenia. The acuphase formulation is indicated for initial treatment of acute psychosis or exacerbation of psychosis, while the depot formulation is best for maintenance.PubMed search ZuclopenthixolDrugBank search Zuclopenthixol
Zuclopenthixol (Zuclopentixol)Cisordinol, Clopixol, AcuphaseClassified as QT prolonging drugAntipsychoticPsychosis PubMed search Zuclopenthixol (Zuclopentixol)DrugBank search Zuclopenthixol (Zuclopentixol)
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