Fenoldopam

Fenoldopam

DrugFenoldopam
Brand namesCorlopam ®
IndicationsShort term management of hypertension, including hypertensive emergency.
Mechanism of action• Systemic Dopamine-1 (D1) receptor agonist.
• Lowers blood pressure while maintaining or increasing kidney perfusion.
EffectsDopamine-1 receptor agonists lower systemic blood pressure and increase renal perfusion.
Time to onset of action50 to 10 minutes
Duration of action30 to 60 minutes
DeliveryIV
DoseInitial infusion dose: 0.1 μg/kg/minute iv.
Titrated at 15 minutes intervals.
Maximum infusion dose: 1.6 μg/kg/minute
Adverse effectsHeadache. Flushing. Tachycardia. Nausea. Hypokalemia. Increased intra-ocular pressure in patients with glaucoma.
CautionUsed cautiously in patients with glaucoma or increased intracranial pressure.
Fenoldopam doses and administration in hypertension.
Updated on 2025-01-18