SYNTAX Score II Calculator
What is SYNTAX Score II?
The SYNTAX Score II is an advanced version of the original SYNTAX Score, designed to improve the prediction of long-term outcomes after revascularization. It incorporates both anatomical (from the original SYNTAX Score) and clinical variables (e.g., age, sex, renal function, left ventricular ejection fraction) to provide a more personalized risk assessment.
Key Variables in SYNTAX Score II
- Anatomical SYNTAX Score: Derived from the original SYNTAX Score, which evaluates the complexity of coronary lesions.
- Clinical Variables:
- Age: Older patients have a higher risk.
- Sex: Females may have different risk profiles.
- Creatinine Clearance: Reduced renal function increases risk.
- Left Ventricular Ejection Fraction (LVEF): Lower LVEF is associated with worse outcomes.
- Unprotected Left Main Disease: Increases complexity and risk.
- Peripheral Vascular Disease (PVD): Indicates systemic atherosclerosis.
- Chronic Obstructive Pulmonary Disease (COPD): Associated with higher perioperative risk.
Clinical Applications
- Personalized Decision-Making: SYNTAX Score II helps determine whether a patient should undergo PCI or CABG based on their risk profile.
- Predicting Outcomes: It predicts 10-year mortality and 5-year major adverse cardiac events (MACE) with greater accuracy than the original SYNTAX Score.
- Heart Team Collaboration: Facilitates discussions between interventional cardiologists and cardiac surgeons to optimize treatment strategies.
Strengths
- Incorporates both anatomical and clinical factors.
- Provides a more personalized risk assessment.
- Validated in large clinical trials, including the SYNTAX trial.
Limitations
- Requires detailed clinical and angiographic data.
- Calculation can be complex without dedicated software.
- May not account for all patient-specific factors (e.g., frailty, comorbidities).
References
- SYNTAX Score II Official Website. https://syntaxscore.org/ .
- ESC/EACTS Guidelines on Myocardial Revascularization. https://syntaxscore.org/index.php/references .
- SYNTAX II 2020: Personalized Decision-Making Tool. https://paper.sciencenet.cn/htmlpaper/2020/10/2020101216555179158941.shtm .