Clinical tools
Aspirin (Acetylsalicylic acid)
Last Updated: 2025-02-01Indications Contraindications Dosage Warnings and precautions Interactions Pharmacodynamic interactions Pharmacokinetic interactions Pregnancy Breastfeeding Fertility Driving and operating machinery Side effects Frequency of Side Effects: Overdose...
Clevidipine
Last Updated: 2025-01-18Clevidipine Drug Clevidipine Brand names Cleviprex ® Indications Hypertension and hypertensive emergency.Treatment of postoperative hypertension. Mechanism of action Ultra-short acting calcium channel blocker (CCB).Half-life: 5...
Clonidine
Last Updated: 2025-01-18Clonidine Drug Clonidine Brand names Catapresan ®, Catapres ®, Dixarit ®, Catapres-TTS ®, Catapres-TTS-1 ®, Duraclon ®, Kapvay ® Indications • Agitated delirium• Analgesia• Hypertension,...
Drug-Induced Cardiotoxicity
Last Updated: 2025-01-23DICTrank: The Largest Reference List of 1318 Human Drugs Ranked by Risk of Drug-Induced Cardiotoxicity Using FDA Labeling. Drug Discovery Today. 2023. DICT = Drug-induced cardiotoxicity
Enalaprilat
Last Updated: 2025-01-18Enalaprilat Enalaprilat is rarely used in hypertensive crisis due to its slow onset, prolonged duration of effect, and significant individual variations in its effect. Drug...
Esmolol
Last Updated: 2025-01-18Esmolol Drug Esmolol Brand names Brevibloc ® Indications Short-term control of ventricular rate (including perioperative tachycardia) and hypertension (including hypertensive emergency, perioperative hypertension). Mechanism of...
Fenoldopam
Last Updated: 2025-01-18Fenoldopam Drug Fenoldopam Brand names Corlopam ® Indications Short term management of hypertension, including hypertensive emergency. Mechanism of action • Systemic Dopamine-1 (D1) receptor agonist.•...
Hydralazine
Last Updated: 2025-01-18Hydralazine Hydralazine is not preferred for hypertensive emergencies due to the high risk of reflex sympathetic stimulation. Drug Hydralazine Brand names Apresoline ®, Bidil ®...
Inotropes and Vasopressors
Last Updated: 2025-01-18Inotropes and vasopressors Vasopressors induce vasoconstriction and increase mean arterial pressure (MAP). Inotropes increase cardiac contractile force (contractility). Several endogenous and synthetic agents exist and...
Labetalol
Last Updated: 2025-01-18Labetalol Drug Labetalol Brand names Trandate ® Indications Mycoardial ischemia. Hypertension.Hypertensive emergency, including in pregnancy.Postoperative hypertension. Mechanism of action Combined beta-adrenergic and alpha-adrenergic blocker with...
Metoprolol
Last Updated: 2025-01-18Metoprolol Drug Metoprolol Brand names Dutoprol ®, Kapspargo ®, Lopressor ®, Lopressor Hct ®, Toprol ®, Seloken ® Indications Mycoardial ischemia.Perioperative hypertension. Mechanism of action...
Nicardipine
Last Updated: 2025-01-18Nicardipine Drug Nicardipine Brand names Cardene ® Indications Hypertension, hypertensive emergency/crisis.Pregnancy induced hypertension.Angina pectorisPrinzmetal’s angina Mechanism of action Nicardipine is a dihydropyridine calcium-channel blocker (CCB)....
Nitroglycerin
Last Updated: 2025-01-18Nitroglycerin Patients using nitroglycerin regularly may have developed tolerance and require higher doses, alternatively nitroprusside to achieve desirable blood pressure lowring effect. Drug Nitroglycerin Brand...
Nitroprusside
Last Updated: 2025-01-18Nitroprusside Drug Nitroprusside Brand names Nipride ®, Nipride RTU ®, Nitropress ®. Indications Pulmonary edema, congestive heart failure.Angina pectoris.Hypertension, hypertensive crisis/emergency.Pulmonary hypertension.Blood pressure control. Mechanism...
Phentolamine
Last Updated: 2025-01-18Phentolamine Drug Phentolamine Brand names Oraverse ®, Rogitine ® Indications Hypertensive crisis. Mechanism of action Phentolamine is a non-selective alpha-adrenergic blocker. Phentolamine reduces blood pressure...
Prasugrel (Effient, Efient, Prasita)
Last Updated: 2025-01-18Brand names: Effient, Efient, Prasita Indications Prasugrel, administered in combination with acetylsalicylic acid (ASA), is indicated for the prevention of atherothrombotic events in adult patients...
QT Drugs: Drugs causing QT prolongation, torsade de pointes (TdP) and long QT syndrome (LQTS)
Last Updated: 2025-01-18A comprehensive list of conditions and drugs that may prolong the QT interval, and cause torsade de pointes (TdP) and long QT syndrome (LQTS) is...
Ticagrelor (Brilinta, Brilique)
Last Updated: 2025-01-18Table 1 provides a summary of the indications, contraindications, dosage, administration, warnings, precautions, and other relevant information for the drug Ticagrelor. Table 1 Summary Indications...
