CPR Hyperthermia and malignant hyperthermia Hyperthermia is characterized by a body temperature exceeding the typical range of 36.5 37.6°C (97.7 99.7°F…

…to malignant ventricular arrhythmias, notably torsade de pointes. This condition is primarily attributed to specific genetic mutations: loss of function mutations in KCNQ1 (LQT1) and…

…malignant hypertension ). Hypertensive emergency is defined as significantly elevated blood pressure (systolic pressure ≥180 mmHg and/or diastolic pressure ≥120 mmHg) with concurrent signs of…

…malignant hypertension ). Hypertensive emergency is defined as significantly elevated blood pressure (systolic pressure ≥180 mmHg and/or diastolic pressure ≥120 mmHg) with concurrent signs of…

…to malignant ventricular arrhythmias, notably torsade de pointes. This condition is primarily attributed to specific genetic mutations: loss of function mutations in KCNQ1 (LQT1) and…

…e. 10 15% of cases). Clinically, patients present with severe chest pain, diaphoresis, hypotension, pulmonary edema, malignant arrhythmias, and rapid progression to cardiogenic shock. Ventricular…

…edge of the tissue is decisive: benign tissue requires about −25 °C for reliable cell death, malignant tissue about −50 °C. The outer limit of…

…creatinine, acid–base status and signs of myocardial ischaemia must be monitored during treatment [4,6]. Important exceptions Condition Overall strategy Common first choices : : : Acute…

…recurrent malignant effusion (often combined with pleurodesis), and in chest trauma and postoperatively. Emergency needle decompression: a clinical suspicion of tension pneumothorax in a haemodynamically…

…and drug related presentations Severe hypertension may result from phaeochromocytoma, monoamine oxidase inhibitor crisis, cocaine intoxication, or other sympathomimetic exposure, including methamphetamine. Abrupt withdrawal of…

…of revascularization outweigh its expected benefits. Haemodynamic and electrical status Haemodynamic instability, cardiogenic shock, acute heart failure related to ongoing ischaemia, life threatening arrhythmias, and…

…depending on the specific drug and dosage [1]. Acute Management and Treatment Alternatives The management of TdP and related malignant ventricular arrhythmias requires a structured…

…syndrome). The prevalence of ARVC is between 0.02 and 0.05% in Europe (Corrado et al). ARVC is more malignant in men, the reason…

…constitute a minority of cardiac tumors, occur in the heart tissue. Approximately 80% of all primary tumors are benign, and the remaining ones are malignant…

…causes of pericardial effusion. Important clinical associations include: Idiopathic or viral pericarditis Malignant pericardial disease Tuberculosis Purulent or bacterial pericarditis Trauma Cardiac surgery and other…

…considered more malignant than anomalous origin of the right coronary artery. High risk anatomical features include: An interarterial course between the aorta and pulmonary artery…

…as mechanisms of inducible ischaemia. The functional impact depends on the bridge’s thickness, length, depth, and location, as well as related biomechanical and fluid…

…morbidity and mortality. This is presumably explained by a higher incidence of malignant ventricular arrhythmias. It has been suggested that the high risk of ventricular…

…likelihood of positive provocation testing, and an increased risk of malignant arrhythmic events (MAEs) [10] . Electrophysiological Mechanisms: Repolarization vs. Depolarization The precise arrhythmogenic mechanism of…

…a highly malignant disorder that must be recognized by any health care provider. A family history of any of the above listed symptoms and manifestations…

…tachycardias should be considered pathological and the task is to clarify the cause of the tachycardia. The cause may range from benign to highly malignant…

…report. A shave biopsy of a pigmented lesion that turns out to be a melanoma can make the Breslow thickness unmeasurable and staging therefore impossible…

…are distinguished by the history and the speed of the course. An AST/ALT ratio 2 with moderately raised values suggests alcohol related liver disease…

…Meningeal carcinomatosis and CNS involvement in haematological malignancy. Investigation of dementia with biomarkers (amyloid, tau, phospho tau). Measurement of the opening pressure in suspected idiopathic…

…Procedure Choice of insertion site The left lower quadrant is the first choice : the abdominal wall is thinner there than on the right, and the…

…a raised filling pressure Marked respiratory variation in mitral and tricuspid inflow The echocardiographic counterpart of pulsus paradoxus Contraindications In overt tamponade with shock there…

…cent. An sPESI of 0 indicates low risk. Anticoagulation A DOAC is the first choice in pulmonary embolism without malignancy and without antiphospholipid syndrome. The…

…commonest cause of upper gastrointestinal bleeding, but the differential diagnosis includes oesophagitis, gastritis, a Mallory Weiss tear, a Dieulafoy lesion, angiodysplasia, malignancy and an aortoenteric…

…investigation as several conditions may affect hemodynamics and the underlying cause is often serious (e. g. malignancy, amyloidosis). In case of suspicion of pericardial disease…

…inflamed tissue — the acidic environment inactivates the anaesthetic. Place a field block in healthy skin around the abscess instead of injecting into it, and expect…

…determine the outcome — that the confirmation of death is carried out in a formally unimpeachable way, and that the donor's organs are maintained physiologically…

…failure — compression of both legs acutely increases preload. Untreated deep vein thrombosis in the acute phase. Septic phlebitis, ongoing soft tissue infection with systemic involvement…

…neutropenic fever is limited, but delayed antibiotics are associated with a worse outcome in sepsis and in several studies of neutropenic patients. In septic shock…

…disorder or known malignancy may suggest specific, nonidiopathic etiologies [2]. Summary of Pain Characteristics The following table synthesizes the key differential diagnoses and their characteristic…