CPR Hyperthermia and malignant hyperthermia Hyperthermia is characterized by a body temperature exceeding the typical range of 36.5 37.6°C (97.7 99.7°F…

…to malignant ventricular arrhythmias, notably torsade de pointes. This condition is primarily attributed to specific genetic mutations: loss of function mutations in KCNQ1 (LQT1) and…

…malignant hypertension ). Hypertensive emergency is defined as significantly elevated blood pressure (systolic pressure ≥180 mmHg and/or diastolic pressure ≥120 mmHg) with concurrent signs of…

…malignant hypertension ). Hypertensive emergency is defined as significantly elevated blood pressure (systolic pressure ≥180 mmHg and/or diastolic pressure ≥120 mmHg) with concurrent signs of…

…to malignant ventricular arrhythmias, notably torsade de pointes. This condition is primarily attributed to specific genetic mutations: loss of function mutations in KCNQ1 (LQT1) and…

…some patients present with severe LMCA stenosis exacerbated by other conditions, and these must also be recognized. Prompt identification of LMCA involvement is therefore critical…

…front , and this is why the margin must be included in the freeze. Contraindications Absolute: Suspected melanoma or any other pigmented lesion of uncertain diagnosis…

…principle, not a universal target. Chronic hypertension shifts autoregulation in the brain and kidneys towards higher pressures. Too rapid a normalisation can therefore cause cerebral…

…recurrent malignant effusion (often combined with pleurodesis), and in chest trauma and postoperatively. Emergency needle decompression: a clinical suspicion of tension pneumothorax in a haemodynamically…

…Malignant hypertension represents an extreme form in which acute microvascular injury occurs, classically involving fibrinoid necrosis of small arteries in the kidneys, retina, and brain…

…heart failure, malignant arrhythmias, or mechanical complications. Risk assessment is intended to identify patients most likely to benefit from early coronary angiography and revascularization, while…

…depending on the specific drug and dosage [1]. Acute Management and Treatment Alternatives The management of TdP and related malignant ventricular arrhythmias requires a structured…

…syndrome). The prevalence of ARVC is between 0.02 and 0.05% in Europe (Corrado et al). ARVC is more malignant in men, the reason…

…a long time and be detected randomly when investigating other conditions. More dramatic onset of symptoms can be seen in arrhythmogenic tumors of the myocardium…

…causes of pericardial effusion. Important clinical associations include: Idiopathic or viral pericarditis Malignant pericardial disease Tuberculosis Purulent or bacterial pericarditis Trauma Cardiac surgery and other…

…considered more malignant than anomalous origin of the right coronary artery. High risk anatomical features include: An interarterial course between the aorta and pulmonary artery…

…and an intramural course. An anomalous left coronary artery is less common but more malignant than an anomalous right coronary artery. Anomalous origin of a…

…morbidity and mortality. This is presumably explained by a higher incidence of malignant ventricular arrhythmias. It has been suggested that the high risk of ventricular…

…current ($I {Na}$) and are identified in 20% to 30% of probands [7] . Historically, expanded genetic panels implicated over 20 other genes (e.g.…

…a highly malignant disorder that must be recognized by any health care provider. A family history of any of the above listed symptoms and manifestations…

…depolarizes the ventricles) passes through the bundle of His, and hence it originates in the atria. In other words: tachycardias with narrow QRS complexes originate…

…a melanoma can make the Breslow thickness unmeasurable and staging therefore impossible; a superficial punch in a case of bullous dermatosis misses the subepidermal split…

…or malignancy. A markedly raised GGT with the other tests normal is most often enzyme induction by alcohol or drugs and is often of no…

…Meningeal carcinomatosis and CNS involvement in haematological malignancy. Investigation of dementia with biomarkers (amyloid, tau, phospho tau). Measurement of the opening pressure in suspected idiopathic…

…sheath, and a cell count plus albumin on the sample. Indications Diagnostic paracentesis: Newly detected ascites — always. Every admission of a patient with known ascites…

…in mitral and tricuspid inflow The echocardiographic counterpart of pulsus paradoxus Contraindications In overt tamponade with shock there are no absolute contraindications other than the…

…cent. An sPESI of 0 indicates low risk. Anticoagulation A DOAC is the first choice in pulmonary embolism without malignancy and without antiphospholipid syndrome. The…

…commonest cause of upper gastrointestinal bleeding, but the differential diagnosis includes oesophagitis, gastritis, a Mallory Weiss tear, a Dieulafoy lesion, angiodysplasia, malignancy and an aortoenteric…

…investigation as several conditions may affect hemodynamics and the underlying cause is often serious (e. g. malignancy, amyloidosis). In case of suspicion of pericardial disease…

…and perirectal Often larger than it appears; risk of fistula Surgeon, often operative management Breast Cosmesis, milk ducts, malignancy differential Surgeon or mammography Sole of…

…whom total brain infarction is not expected to occur within a reasonable time, and in whom death is judged likely within 180 minutes of treatment…

…closer monitoring — the patient cannot feel pressure injury Peripheral neuropathy of other cause As above Severe pain Titrate the pressure up gradually Rheumatoid arthritis with…

…the only signs of infection. Corticosteroids and other immunosuppressive treatments can blunt the febrile response. A neutropenic patient with a suspected infection and organ dysfunction…

…disorder or known malignancy may suggest specific, nonidiopathic etiologies [2]. Summary of Pain Characteristics The following table synthesizes the key differential diagnoses and their characteristic…