CPR Hyperthermia and malignant hyperthermia Hyperthermia is characterized by a body temperature exceeding the typical range of 36.5 37.6°C (97.7 99.7°F…

…which predisposes individuals to malignant ventricular arrhythmias, notably torsade de pointes. This condition is primarily attributed to specific genetic mutations: loss of function mutations in…

…malignant hypertension ). Hypertensive emergency is defined as significantly elevated blood pressure (systolic pressure ≥180 mmHg and/or diastolic pressure ≥120 mmHg) with concurrent signs of…

…malignant hypertension ). Hypertensive emergency is defined as significantly elevated blood pressure (systolic pressure ≥180 mmHg and/or diastolic pressure ≥120 mmHg) with concurrent signs of…

…which predisposes individuals to malignant ventricular arrhythmias, notably torsade de pointes. This condition is primarily attributed to specific genetic mutations: loss of function mutations in…

…malignant ventricular arrhythmias, or sudden cardiac death. The resulting extensive ischemia causes immediate myocardial stunning (akinesia) and electrical instability. Fewer than 1% of patients with…

…edge of the tissue is decisive: benign tissue requires about −25 °C for reliable cell death, malignant tissue about −50 °C. The outer limit of…

…levels, particularly in pregnancy [1,2]. Malignant hypertension is not entirely synonymous with a hypertensive emergency. The term denotes severe hypertension with advanced hypertensive retinopathy…

…new pleural effusion of unclear cause. An effusion not confidently explained by heart failure must be aspirated. Suspected empyema or complicated parapneumonic effusion. Suspected malignancy…

…heart, aorta, kidneys, or other vascular beds. Malignant hypertension represents an extreme form in which acute microvascular injury occurs, classically involving fibrinoid necrosis of small…

…myocardial necrosis, haemodynamic deterioration, heart failure, malignant arrhythmias, or mechanical complications. Risk assessment is intended to identify patients most likely to benefit from early coronary…

…to renal or hepatic impairment or the inhibition of cytochrome P450 metabolism [1]. Nonmodifiable risk factors encompass female sex, underlying genetic predisposition, structural heart disease…

…al). ARVC is more malignant in men, the reason for which remains elusive. Gene mutations can be confirmed in roughly 60% of individuals with ARVC…

…constitute a minority of cardiac tumors, occur in the heart tissue. Approximately 80% of all primary tumors are benign, and the remaining ones are malignant…

…a life threatening clinical syndrome in which increased intrapericardial pressure compresses the heart and impairs ventricular filling. It generally results from accumulation of pericardial fluid…

…exercise. Anomalous origin of the left coronary artery is less frequent but is considered more malignant than anomalous origin of the right coronary artery. High…

…left coronary artery is less common but more malignant than an anomalous right coronary artery. Anomalous origin of a coronary artery from the pulmonary artery…

…presumably explained by a higher incidence of malignant ventricular arrhythmias. It has been suggested that the high risk of ventricular arrhythmias is due to the…

…increased risk of malignant arrhythmic events (MAEs) [10] . Electrophysiological Mechanisms: Repolarization vs. Depolarization The precise arrhythmogenic mechanism of BrS remains a subject of intense debate…

…syndrome is a highly malignant disorder that must be recognized by any health care provider. A family history of any of the above listed symptoms…

…tachycardias should be considered pathological and the task is to clarify the cause of the tachycardia. The cause may range from benign to highly malignant…

…case of bullous dermatosis misses the subepidermal split. Choose the technique according to the diagnostic question, not according to what is quickest. Indications Suspected malignancy…

…or malignancy. A markedly raised GGT with the other tests normal is most often enzyme induction by alcohol or drugs and is often of no…

…Meningeal carcinomatosis and CNS involvement in haematological malignancy. Investigation of dementia with biomarkers (amyloid, tau, phospho tau). Measurement of the opening pressure in suspected idiopathic…

…sample. Indications Diagnostic paracentesis: Newly detected ascites — always. Every admission of a patient with known ascites. Clinical deterioration in a cirrhotic patient with ascites: fever…

…purulent pericarditis, tuberculosis or malignancy. Tamponade is a clinical diagnosis supported by echocardiography: Finding Comment : : Hypotension, distended neck veins, muffled heart sounds Beck's triad;…

…embolism: Criterion Points : : Clinical signs of deep vein thrombosis 3 Pulmonary embolism is the most likely diagnosis 3 Heart rate 100/min 1.5 Immobilisation ≥…

…the commonest cause of upper gastrointestinal bleeding, but the differential diagnosis includes oesophagitis, gastritis, a Mallory Weiss tear, a Dieulafoy lesion, angiodysplasia, malignancy and an…

…underlying cause is often serious (e. g. malignancy, amyloidosis). In case of suspicion of pericardial disease, in the first place, an echocardiographic examination is done…

… risk of fistula Surgeon, often operative management Breast Cosmesis, milk ducts, malignancy differential Surgeon or mammography Sole of the foot Deep compartments Orthopaedic surgeon Close…

…on a donor card, or through statements made to the next of kin. Active malignancy with a risk of transmission (an individual assessment; certain tumour…

…0.5 or toe pressure < 30 mmHg. Decompensated heart failure — compression of both legs acutely increases preload. Untreated deep vein thrombosis in the acute…

…occurs 7 to 14 days after a course of chemotherapy, but the timing varies considerably between regimens. Neutropenia can also be caused by haematological malignancy…

…Diagnosis of Chest Pain: A Clinical Overview The evaluation of acute chest discomfort requires a systematic differential diagnosis, as the syndrome associated with ischemic heart…