…The drug possesses an active, acetylated metabolite with a half life exceeding 80 hours, allowing for sustained hemodynamic effects for days after the infusion is…

…is generally sufficient for the assessment of pH and bicarbonate. An arterial blood gas is needed mainly when concomitant respiratory failure or an exact assessment…

…Indications Infusion of vesicant solutions: vasopressors, concentrated potassium, cytotoxic drugs, parenteral nutrition. The need for several simultaneous, incompatible infusions. Haemodialysis, plasmapheresis or other extracorporeal therapy…

…protocol. Usually a bolus followed by repeated doses or an infusion Suspected adrenal crisis Give the corticosteroid immediately. Do not wait for laboratory results. Take…

…In parallel with the drug treatment Resuscitation, investigation and drug treatment must proceed simultaneously. Do not wait for laboratory results, CT or EEG before the…

…calcium channel blocker. Clevidipine is highly selective for vascular smooth muscle cells and has little or no effect on myocardial contractility or conduction. Clevidipine reduces…

Esmolol Drug Esmolol Brand names Brevibloc ® Indications Short term control of ventricular rate (including perioperative tachycardia) and hypertension (including hypertensive emergency, perioperative hypertension). Mechanism…

Fenoldopam Drug Fenoldopam Brand names Corlopam ® Indications Short term management of hypertension, including hypertensive emergency. Mechanism of action • Systemic Dopamine 1 (D1) receptor agonist…

Hydralazine Hydralazine is not preferred for hypertensive emergencies due to the high risk of reflex sympathetic stimulation. Drug Hydralazine Brand names Apresoline ®, Bidil ®…

Info This drug manual is provided for use in patients with hypertensive emergency (also referred to as hypertensive crisis or malignant hypertension ). Hypertensive emergency is…

…minutes Duration of action 2 to 4 hours Delivery IV Dose Can be given as repeated intravenous bolus injections or as a constant dose infusion…

Nicardipine Drug Nicardipine Brand names Cardene ® Indications Hypertension, hypertensive emergency/crisis. Pregnancy induced hypertension. Angina pectoris Prinzmetal's angina Mechanism of action Nicardipine is…

…tolerance and require higher doses, alternatively nitroprusside to achieve desirable blood pressure lowring effect. Drug Nitroglycerin Brand names Gonitro ®, Minitran ®, Mylan nitro ®…

…minute) should never be used for mor than 10 minutes. Administer sodium thiosulfate (cyanide into thiocyanate) and terminate infusion of nitroprusside if cyanide toxicity is…

Phentolamine Drug Phentolamine Brand names Oraverse ®, Rogitine ® Indications Hypertensive crisis. Mechanism of action Phentolamine is a non selective alpha adrenergic blocker. Phentolamine reduces…

…in a monitored clinical setting appropriate for cardioversion. Administration of vernakalant Vernakalant (Brinavess) is administered as an infusion. The infusion is diluted to 4 mg…

…inadequate, consider an intravenous bolus of epinephrine (20 50 μg) or an epinephrine infusion (0.01 to 0.10 μg/kg/min). Pediatric…

Cardiology This drug manual is provided for use in patients with hypertensive emergency (also referred to as hypertensive crisis or malignant hypertension ). Hypertensive emergency is…

…infusion. Refer to Table 2 for a comparison between levosimendan, milrinone and dobutamine. Mechanisms of action Levosimendan exhibits both inotropic and vasodilatory effects. The drug…

…immediately. Stop a suspected drug infusion or contrast medium. Remove a visible bee sting. Never delay adrenaline in order to identify or remove the allergen…

…second attempt). Vasoactive infusions Drug Dose range Primary effect Used in : : : : Noradrenaline 0.05–0.5 µg/kg/min α₁ — vasoconstriction Septic and distributive shock

…manages the pump themselves where possible. In impaired consciousness or DKA: remove the pump and change to an infusion or injections Drugs for type 2…

…started in an opioid naive patient, or when a conversion between drugs is made without reduction for incomplete cross tolerance. Indications Acute severe nociceptive pain…

…to try yet another dose. Chronotropic support is given as an infusion of isoprenaline, adrenaline or dopamine according to local practice, and does not replace…

…a central venous catheter for longer treatment. Sodium bicarbonate 50 mg/mL (corresponding to 0.6 mmol sodium bicarbonate per mL) for bolus and infusion…

…Figure 1). Below follows a drug manual for use in the CCU (coronary care unit), ICU (intensive care unit) or ER (emergency room). Careful electrocardiographic…

…10 minutes can be utilized for breakthrough ventricular tachycardia (VT) or ventricular fibrillation (VF). IV infusions can be safely continued for 2 to 3 weeks…

…infusion of agents to stress the AV node and His Purkinje system, such as isoproterenol and/or procainamide. EPS with isoproterenol is also recommended for…

…Figure 1). Below follows a drug manual for use in the CCU (coronary care unit), ICU (intensive care unit) or ER (emergency room). Careful electrocardiographic…

…50% renal elimination. • Typically the first choice of drug. • Effective in sinus bradycardia or AV node block. • Dose <0.5 mg may worsen bradycardia and…

…6°C (97.7 99.7°F). It arises when heat production or acquisition surpasses the body's capacity for heat elimination. Hyperthermia can induce an inflammatory…

…marked QRS widening, a sine wave pattern, or a need for repeated calcium treatment. Urgent investigations As a rule, take: Plasma potassium as a central…

…for as long as the patient remains unconscious. The evidence Trial Question Result : : : TTM (2013) 33 °C versus 36 °C No difference in mortality or…

…Drainage material: rubber dam drain, a strip cut from a glove, petrolatum impregnated packing strip or a vessel loop for loop drainage. Gauze, absorbent dressing…

…Indications Condition Procedure : : Acute paronychia with fluctuance or visible pus Incision and drainage Acute paronychia without pus formation Antibiotics and soaks alone Ingrown nail with…

…The varying inclusion criteria in these registries explain the marked differences in characteristics and outcomes across the data sources for out of hospital cardiac arrest…

…necrosis, bleeding, or pleural incision may expose cardiac antigens and initiate an inflammatory response. The presence of antibodies directed against cardiac tissue, the latent interval…

…the remaining ones are malignant. • Secondary cardiac tumours have spread to the heart by metastasis or invasion from surrounding tissue. Differential Diagnostics There are several…

…scalpel for the skin incision, sterile dressings, pressure dressing. Procedure 1. Place the patient in the lateral position with the knees drawn up , or prone…

…not hold in all patients. Error in Calculation : The original formula’s inclusion of “ 100” for Qp/Qs is likely a typo; standard practice uses…