…TLC Total lung capacity, which requires body plethysmography DLCO Diffusing capacity for carbon monoxide An obstructive pattern: FEV₁/FVC below the lower limit of normal…

Procedurer The insertion itself is rarely the difficult part — it is the confirmation of the position that determines whether the tube is safe. A misplaced…

…Refraction artifact Reflection and refraction occur when ultrasound passes tissue boundaries. Tissue boundaries represent acoustic reflectors at which some of the ultrasound energy is reflected…

…lower part of the target range. Paraquat poisoning — oxygen worsens the lung injury. Discuss with your national or regional poison control centre. An open flame…

…coronary artery disease (CAD). It combines echocardiographic assessment of left ventricular (LV) structure and function with exercise or pharmacological stress. The physiological basis is an…

…are rarely useful, as myocardial concentration—which correlates best with total cumulative dose—may be a better predictor of long term tolerability. Hemodynamic Effects Amiodarone…

…stunning . This is a protective mechanism since the cessation of contractions leads to a marked reduction in cell metabolism and thus prolongs survival. Myocardial stunning…

…category of elevated blood pressure, defined as office SBP 120–139 mmHg or DBP 70–89 mmHg. This distinction supports a risk based approach because…

…in atrial fibrillation Criteria for dose reduction according to FASS : : : Apixaban 5 mg × 2 2.5 mg × 2 if at least two of: age ≥ 80…

…By inhibiting the intracellular portion of its transmembrane pore, ivabradine reduces the slope of diastolic depolarisation and produces a dose dependent reduction in sinus rate…

…benefit of coronary intervention while limiting major and clinically relevant bleeding. Long term antiplatelet therapy after STEMI is associated with approximately a 25% reduction in…

…Three questions come up again and again on call: which dose, how long to interrupt treatment before a procedure, and how to reverse in bleeding…

…not reverse coronary atherosclerosis. Long term benefit therefore depends on the integration of revascularisation with guideline directed medical therapy and secondary prevention. Clinical Presentation and…

…The management of TdP and related malignant ventricular arrhythmias requires a structured approach focusing on rhythm stabilization, relief of triggers, and reduction of sympathetic drive…

…Indications Acute urinary retention. Chronic urinary retention with renal impairment or a large residual volume. A need for accurate measurement of urine output in a…

Cardiology Clinical medicine Definition and Pathophysiology Dietary patterns are the overall combinations of foods habitually consumed rather than isolated nutrients considered independently. For cardiometabolic health…

…and clinician inertia and contributes to inadequate long term control. The treatment objective is individualized blood pressure reduction sufficient to reduce cardiovascular risk while preserving…

…outcome Reported benefit of cessation Cardiovascular disease overall Substantial reduction in cardiovascular events and mortality Established coronary disease Approximately 36% lower risk of premature death…

…a drop in blood pressure, and finally a reduction in heart rate. This sequence is characteristic of neurally mediated hypotension. Clinical Presentation and Symptoms Vasovagal…

…The annual risk of sudden cardiac arrest is <1% and median survival is 3 years. Long term prognosis in aortiv stenosis is presented in Figure…

… the reduction in a subgroup with diabetes was approximately 19.1%. The drug also lowers hsCRP. In a population of individuals unable or unwilling to…

…disruption. Fewer than 5% of thin capped fibroatheromas have been identified as the source of an acute myocardial infarction during long term follow up. Moreover…

…considerations Type 1 Contrast staining of the arterial wall with multiple lumens or radiolucent channels The classic appearance and usually readily recognized Type 2 Long…

…Condition Overall strategy Common first choices : : : Acute aortic syndrome Immediate rate control and rapid reduction of the systolic blood pressure towards 100 to 120 mmHg…

…exact antithrombotic strategy may differ when long term OAC is also indicated. Possible shortening of DAPT A duration of 6 months after ACS is generally…

…of life, repeated hospital presentations and angiography, and increased short and long term adverse cardiovascular outcomes. Clinical Presentation and Symptoms Symptoms may resemble those of…

…The resulting mild reduction in blood pressure is often accompanied by a compensatory rise in cardiac output. Although these changes are usually of limited clinical…

…For every 1°C reduction in body temperature, there is a 6% decrease in oxygen consumption (Wood et al.). Evaluating the vitality of a hypothermic individual…

…hours duration): Due to cellular adaptations, rapid correction carries the risk of inducing osmotic demyelination syndrome (ODS). It is therefore recommended to raise serum sodium…

…an orthopaedic surgeon before attempting reduction. Posterior shoulder dislocation, which is often associated with fracture and requires an orthopaedic surgeon. Dislocation of a native hip …

…integrated assessment of six components: Symptoms Exercise performance (functional capacity, exercise capacity) Heart rate: maximal heart rate, heart rate response Blood pressure reaction ECG reaction:…

…progressive reduction of coronary blood flow sufficient to produce myocardial ischaemia and, when prolonged or severe, myocardial necrosis. It most commonly reflects atherothrombosis: disruption of…

…on the size of the thrombus and the plaque. The patient will experience severe chest pain due to the abrupt reduction of coronary blood flow…

…ostia. It remains the reference standard for defining the extent of coronary artery disease because it provides anatomical information while permitting functional assessment and, when…

…radiotracers emit gamma photons directly. These gamma rays are detected by gamma cameras to create tomographic images of the left ventricle. In PET (Positron Emission…

…term to describe a reduction of blood flow to tissues and organs. A few decades later Cohnheim demonstrated that ligation of the left anterior descending…

…reflection of the electrical potentials generated by the left ventricle. QRS duration QRS duration is the time duration from the start to the end of…

…92 percent until the risk of hypercapnia has been assessed. 3. Take an arterial blood gas in respiratory compromise, low saturation, suspected carbon dioxide retention…

…functional) capacity. Functional capacity is a strong predictor of both cardiovascular and overall mortality, offering incremental prognostic data beyond perfusion imaging and ECG reaction. Coronary…

Echocardiography Generating the ultrasound image The ultrasound transducer generates short bursts (pulses) of ultrasound waves. Reflected ultrasound waves are analyzed by the machine during the…

…initiation to restoration of coronary flow. Early reperfusion, reduction of myocardial energy requirements and mitigation of reperfusion injury are complementary objectives of initial STEMI management…

…LDL C reduction required is greater than can reasonably be obtained with a statin alone but does not necessarily require the larger effect of a…

…complex is actually a reflection of left ventricular depolarization. QRS duration is the time interval from the onset to the end of the QRS complex…

…by about 13% of their length, but the sum of all contractions results in a reduction of the diameter and length of the ventricle by…

…reduction of the ST segment elevation by 50%) within 60 minutes after administration of thrombolysis. Otherwise, one must consider rescue PCI. For the purpose of…

…A1c (HbA1c) reduction, blood pressure, lipids and smoking cessation. Weight loss was considered extremely difficult across patient categories. However, the emergence of incretin based therapies…

Psykiatri Akutsjukvård Lathundar Rapid summary Alcohol withdrawal occurs after an abrupt reduction or cessation of prolonged and heavy alcohol intake. The condition can develop despite…

…Congestion is a central expression of the heart failure syndrome and reflects excessive retention of sodium and water, with expansion of both the intravascular and…

Akutsjukvård Lathundar Basic principle Anaphylaxis is a rapidly developing systemic hypersensitivity reaction that can cause life threatening compromise of the airway, breathing or circulation. Skin…

Referensvärden A diagnosis of hypertension is not made on a single reading. It requires repeated measurements on at least two occasions, and preferably confirmation by…

…The urgency varies: Object Urgency : : Button battery Immediately — leakage of fluid causes a chemical burn Two or more magnets (including in different nostrils) Immediately — pressure…

…crisis. Mechanism of action Phentolamine is a non selective alpha adrenergic blocker. Phentolamine reduces blood pressure while increasing catecholamine activity. Effects Primarily causes afterload reduction…

…and pathophysiology Acute limb ischaemia (ALI) is an abrupt reduction in arterial perfusion of an upper or lower limb that causes tissue metabolic requirements to…

…visual diameter reduction. Relevant determinants include: Lesion eccentricity Vessel tortuosity Calcification Plaque rupture or asymmetric filling defects Serial lesions Vessel size The relationship of the…

…this form of hypertension was a physiological reaction that was necessary to maintain normal hemodynamics, hence the term essential . However, a growing body of science…

…can be counteracted with simultaneous administration of beta blockers). Effects Induces arteriolar vasodilation without effects on venous circulation. The reduction in systemic vascular resistance (SVR…

…and acute coronary syndromes (ACS). Its principal therapeutic objective is reduction of low density lipoprotein cholesterol (LDL C), the primary lipid target in contemporary secondary…

…dioxide retention for the latter. The treatment is also time limited by its very nature: a patient who has not responded within a couple of…

…disease (ASCVD). Atherosclerosis develops through the progressive deposition and retention of LDL C and other apoB containing lipoproteins within the arterial wall. This initiates inflammatory…

…associated with increased ASCVD risk. Management in this range therefore focuses principally on ASCVD prevention and reduction of LDL C, non HDL C and apolipoprotein…