…missed, only one tablet should be taken at the next regular time. Use with caution in patients with asthma/chronic obstructive pulmonary disease (COPD). Dyspnea…

…induces vasodilation in coronary, renal, cerebral and mesenteric vessels. Few Dopamine medium dose Cardiogenic shock Vasodilatory shock Heart failure (HF), acute Heart failure (HF), chronic…

…induces vasodilation in coronary, renal, cerebral and mesenteric vessels. Few Dopamine medium dose Cardiogenic shock Vasodilatory shock Heart failure (HF), acute Heart failure (HF), chronic…

…receptors and induces vasodilatation in the coronary, renal, cerebral and mesenteric vessels. Few Dopamine — intermediate dose Cardiogenic shock. Vasodilatory shock. Heart failure, acute or chronic…

…temporal association is present; contrast induced AKI should be reserved for the smaller subgroup in which iodinated contrast is considered causally responsible. This distinction is…

CPR It is commonly stated that approximately 80% of all cardiac arrests are caused by acute or chronic coronary artery disease, with the latter being…

…Because of the drug's unusual pharmacokinetics, serious arrhythmia indications, and potential adverse effects, consideration should be given to initiating therapy with the patient hospitalized…

…of 1318 Human Drugs Ranked by Risk of Drug Induced Cardiotoxicity Using FDA Labeling . Drug Discovery Today. 2023. DICT = Drug induced cardiotoxicity Trade Name…

…Clinicians should maintain a high index of suspicion for drug induced arrhythmias in patients receiving agents known to alter the electrical properties of the heart…

Nicardipine Drug Nicardipine Brand names Cardene ® Indications Hypertension, hypertensive emergency/crisis. Pregnancy induced hypertension. Angina pectoris Prinzmetal's angina Mechanism of action Nicardipine is…

…of the drugs listed below may be used to treat hypertensive emergencies. The desired time to action, contraindications and risk of adverse effects should guide…

…of the drugs listed below may be used to treat hypertensive emergencies. The desired time to action, contraindications and risk of adverse effects should guide…

…malignant arrhythmias should undergo continuous electrocardiogram monitoring throughout the entire peri operative period to assess rhythm stability [10]. References International guideline (EU) — Drug Induced Torsades…

…food allergies, insect stings, and drug induced reactions. Approximately 90% of anaphylactic cardiac arrests present with pulseless electrical activity (PEA) as the initial rhythm, while…

…Go through the medication and any herbal preparations carefully — drug induced liver injury is the commonest cause of acute liver failure in the Nordic countries…

…clearance must be assessed prior to initiation and monitored continuously during therapy. Hypokalemia is a significant risk factor for drug induced torsades de pointes; therefore…

…saturation, chest movement and a blood gas. Ventilate by mask in opioid induced respiratory depression while naloxone is prepared C Pulse, blood pressure, peripheral perfusion…

…any. Treatment of atrial tachycardia Discontinuation of digoxin is typically sufficient in patients whose atrial tachycardia is induced by the drug. Management of all other…

Nitroprusside Drug Nitroprusside Brand names Nipride ®, Nipride RTU ®, Nitropress ®. Indications Pulmonary edema, congestive heart failure. Angina pectoris. Hypertension, hypertensive crisis/emergency. Pulmonary…

Clonidine Drug Clonidine Brand names Catapresan ®, Catapres ®, Dixarit ®, Catapres TTS ®, Catapres TTS 1 ®, Duraclon ®, Kapvay ® Indications • Agitated delirium…

CPR Poisoning and drug toxicity In adolescents and young adults, intoxication events leading to cardiac arrest are notably prevalent, primarily due to the misuse of…

…high risk of reflex sympathetic stimulation. Drug Hydralazine Brand names Apresoline ®, Bidil ® Mechanism of action • Induces arteriolar vasodilation. No effect on venous circulation…

…tolerance and require higher doses, alternatively nitroprusside to achieve desirable blood pressure lowring effect. Drug Nitroglycerin Brand names Gonitro ®, Minitran ®, Mylan nitro ®…

…process. A broad spectrum of pharmacologic agents can induce bradycardia or conduction disorders. These include beta blockers, non dihydropyridine calcium channel blockers, antiarrhythmic drugs (amiodarone…

…vasoactive agents are categorised according to their distinct pharmacodynamic mechanisms. These drugs are broadly utilised to augment myocardial contractility, manipulate systemic and pulmonary vascular resistance…

…blood pressure measurement. Resuscitation trolley with defibrillator, oxygen, suction and emergency drugs in the room. Staff with current CPR competence; a physician available. Patient preparation…

…Due to denervation, which makes the sinus and AV nodes supersensitive to the drug, the initial dose should be reduced to 3 mg. Dipyridamole therapy…

…T wave should be included in the measurement. This may result in an overestimation of the QT interval. If the patient uses QT prolonging drugs…

…repeated measurements Hypertension requiring at least four antihypertensive drugs despite control Hypertension with spontaneous or diuretic induced hypokalaemia Hypertension with an adrenal incidentaloma Hypertension associated…

…may induce Brugada syndrome in individuals with underlying genetic susceptibility. If ECG changes consistent with Brugada syndrome develop during treatment with flecainide, the drug must…

…of drugs (notably beta blockers, digitalis, verapamil, diltiazem, amiodarone, clonidine) – These drugs affect the pacemaker cells in the sinoatrial node. They may also induce conduction…

…and create a highly prothrombotic endothelial surface. Furthermore, AF induces a systemic hypercoagulable state, characterized by elevated biomarkers such as D dimer, von Willebrand factor…

Myocardial ischemia and infarction Introduction Drug eluting stents (DES) are the predominant device used during percutaneous coronary intervention (PCI). They evolved from balloon angioplasty and…

…antihypertensive drug therapy. For grade 1 hypertension, pharmacological treatment has demonstrated cardiovascular benefit, although in younger individuals with low short term risk, lifetime benefit should…

Clevidipine Drug Clevidipine Brand names Cleviprex ® Indications Hypertension and hypertensive emergency. Treatment of postoperative hypertension. Mechanism of action Ultra short acting calcium channel blocker…

Esmolol Drug Esmolol Brand names Brevibloc ® Indications Short term control of ventricular rate (including perioperative tachycardia) and hypertension (including hypertensive emergency, perioperative hypertension). Mechanism…

Fenoldopam Drug Fenoldopam Brand names Corlopam ® Indications Short term management of hypertension, including hypertensive emergency. Mechanism of action • Systemic Dopamine 1 (D1) receptor agonist…

Labetalol Drug Labetalol Brand names Trandate ® Indications Mycoardial ischemia. Hypertension. Hypertensive emergency, including in pregnancy. Postoperative hypertension. Mechanism of action Combined beta adrenergic and…

Metoprolol Drug Metoprolol Brand names Dutoprol ®, Kapspargo ®, Lopressor ®, Lopressor Hct ®, Toprol ®, Seloken ® Indications Mycoardial ischemia. Perioperative hypertension. Mechanism of…

Phentolamine Drug Phentolamine Brand names Oraverse ®, Rogitine ® Indications Hypertensive crisis. Mechanism of action Phentolamine is a non selective alpha adrenergic blocker. Phentolamine reduces…

Procedurer Oxygen is a drug and must be prescribed as one: with an indication, a route of administration and a target range for the saturation…

…factors Concomitant nonsteroidal anti inflammatory drugs Corticosteroid therapy Other antiplatelet or antithrombotic drugs Selective serotonin reuptake inhibitors Patient selection Aspirin should not be prescribed routinely…

…orally when gut function is intact. Oral vancomycin (only for C. difficile) is likewise dosed independently of renal function. Require drug concentration monitoring Drug Comment…

…Doses in atrial fibrillation Drug Standard dose Reduced dose and criterion : : : Apixaban 5 mg twice daily 2.5 mg twice daily if at least two…

…Prescribe basal insulin, mealtime insulin and the correction dose as three separate entries on the drug chart. Glucose targets on the ward Situation Target plasma…

…effect, and significant individual variations in its effect. Drug Enalaprilat Brand names Vasotec IV ® Indications Hypertension and hypertensive emergency. Acute left ventricular failure. Mechanism…

…gov/pubmed/?term=Abarelix+AND+(%22QT%22+OR+Torsad " PubMed search Abarelix ) DrugBank search Abarelix Abexinostat None Classified as QT prolonging drug in DrugBank. No data…

…therapy in chronic coronary syndrome (CCS) is directed primarily at reducing myocardial ischaemia and relieving anginal symptoms, while maintaining tolerability and adherence. Selection should be…

…frequent cause of PCI failure, despite its substantially lower incidence with drug eluting stents (DES) than with bare metal stents (BMS). Clinical ISR is generally…

…drug treatment and transport planning [1,5]. Symptom duration Under 12 hours: reperfusion is indicated in persisting STEMI. 12 to 48 hours: primary PCI should…

…walking Vestibular neuritis, cerebellar or brainstem infarction, haemorrhage, drug toxicity, demyelination HINTS plus by a trained examiner if nystagmus is present, neurological examination, gait and…

…of withdrawal and the risk of seizures and delirium [1,2]. In delirium tremens the aim should be a calm, mildly somnolent but rousable patient…

…apnoea). Suspected hypotension: dizziness, syncope, autonomic dysfunction, adverse drug effects. Wide variability between measurements. Hypertension in pregnancy. Contraindications There are no absolute contraindications. Refrain or…

…time, serious adverse effects are uncommon when the correct dose is given intramuscularly [2,3]. When should anaphylaxis be suspected? Anaphylaxis is a clinical diagnosis…

…and in people under 18 years of age, where iso BMI or percentile charts should be used. Waist circumference Measure the waist between the lowest…

…patient. Rate control in the stable patient Drug Situation Comment : : : Beta blocker (metoprolol) First choice in most cases The IV dose is titrated slowly. Caution…

…several non pharmacological measures at the same time, and use drugs only in severe agitation or marked distress. Delirium is an acute neuropsychiatric syndrome and…

…tension pneumothorax. No drug has been shown to improve the neurological outcome in cardiac arrest. High quality compressions with minimal interruptions and early defibrillation are…

…drugs under careful observation [3,4]. A markedly raised blood pressure without acute target organ damage should not normally be lowered rapidly with intravenous drugs…

…alone [2]. A markedly raised blood pressure without acute organ damage should as a rule not be lowered rapidly with intravenous drugs. Restart or optimise…