A comprehensive list of conditions and drugs that may prolong the QT interval, and cause torsade de pointes (TdP) and long QT syndrome (LQTS) is presented below. With regards to drugs, the risk of QT prolongation and TdP varies markedly across the list but tends to be rather similar within a drug class. While the risk of TdP is well-defined for many of these agents, many are classified as QT-prolonging solely based on their drug class or presumed pharmacodynamic effects. We provide a direct PubMed search for each drug and we recommend the reader to use this link to assess the literature.

Medical conditions

Category	Condition
Congenital conditions	Jervell and Lange-Nielsen syndrome
	Romano-Ward syndrome
	Idiopathic congenital long QT syndrome (LQTS)
Metabolic disorders	Hypokalemia
	Hypomagnesemia
	Hypocalcemia
	Starvation
	Anorexia nervosa
	Liquid protein diets
	Hypothyroidism
Bradyarrhythmia	Sinus bradycardia
	Sinus node dysfunction
	AV-blocks

Drugs

Drug	Brands	TdP Risk	Class	Clinical Use	Drugbank Description	Pubmed Record	DrugBank Record
Abarelix	Plenaxis	Classified as QT prolonging drug in DrugBank. No data on QT prolongation or risk of torsade de pointes in PubMed.	GnRH Antagonist	Cancer (prostate)	Synthetic decapeptide antagonist to gonadotropin releasing hormone (GnRH).	PubMed search Abarelix)	DrugBank search Abarelix
Abexinostat	None	Classified as QT prolonging drug in DrugBank. No data on QT prolongation or risk of torsade de pointes in PubMed.			Abexinostat has been used in trials studying the treatment of Sarcoma, Lymphoma, Leukemia, Lymphocytic, and Hodgkin Disease, among others. It is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase...	PubMed search Abexinostat)	DrugBank search Abexinostat
Abiraterone	Zytiga, Abiratas, Abretone, Abirapro	Several cases of QT prolongation and torsade de pointes reported to the FDA in postmarketing studies.	Anti-androgen	Cancer (Prostate)	Abiraterone is an antiandrogen used in the treatment of prostate cancer.	PubMed search Abiraterone)	DrugBank search Abiraterone
Aceprometazine	None	Classified as QT prolonging drug in DrugBank. No data on QT prolongation or risk of torsade de pointes in PubMed.	Drug with neuroleptic and anti-histamine properties.	Sleep disorder	Aceprometazine is often used in combination with meprobamate for the treatment of sleep disorders.	PubMed search Aceprometazine)	DrugBank search Aceprometazine
Acetyldigoxin		Classified as QT prolonging drug in DrugBank. No data on QT prolongation or risk of torsade de pointes in PubMed.				PubMed search Acetyldigoxin)	DrugBank search Acetyldigoxin
Aclarubicin	Aclarubicin	Several cases of QT prolongation and ventricular fibrillation have been reported. See PubMed link.				PubMed search Aclarubicin)	DrugBank search Aclarubicin
Acrivastine		QT prolongation has been described (see PubMed link).			An antihistamine agent used for the symptomatic relief of seasonal allergic rhinitis, rhinorrhea, pruritus, lacrimation, and nasal congestion.	PubMed search Acrivastine)	DrugBank search Acrivastine
Ajmaline	Ajimalin	Few cases with torsade de pointes described (see PubMed link).	Class IA antiarrhythmic	Arrhythmias	An antiarrhythmic used to manage several tachycardias.	PubMed search Ajmaline) Kaul et al Haverkamp et al	DrugBank search Ajmaline
Albuterol (Salbutamol)	Proventil, Ventolin, Ventolin-HFA, Accuneb, Combivent, Vospire-ER, ProAir HFA, Duoneb	Low risk	Bronchodilator	Asthma	Beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms	PubMed search Albuterol (salbutamol))	DrugBank search Albuterol (salbutamol)
Alfuzosin	Uroxatral	Low to moderate risk	Alpha-1 adrenergic blocker	Benign prostatic hyperplasia	An alpha-1 adrenergic antagonist used in the symptomatic management of benign prostatic hypertrophy (BPH).	PubMed search Alfuzosin)	DrugBank search Alfuzosin
Alimemazine	Panectyl*	Classified as QT prolonging drug in Drugbank			An antihistamine agent used to prevent and relieve allergic conditions which cause pruritus and other allergic skin conditions, including urticaria.	PubMed search Alimemazine)	DrugBank search Alimemazine
Alimemazine (Trimeprazine)	Panectyl	Low to moderate risk	Antihistamine	Allergic reactions		PubMed search Alimemazine (Trimeprazine)+AND+(%22QT%22+OR+Torsad*))	DrugBank search Alimemazine (Trimeprazine)
Amantadine	Symmetrel, Symadine, Gocovri, Osmolex	Low to moderate risk	Antiviral	Viral infection (Influenza), Parkinson's disease	A medication used to treat dyskinesia in Parkinson's patients receiving levodopa, as well as extrapyramidal side effects of medications.	PubMed search Amantadine)	DrugBank search Amantadine
Amifampridine	Firdapse, Ruzurgi	Classified as QT prolonging drug. No cases described in PubMed (see link). Presumably low risk.			A voltage gated potassium channel blocker used to treat Lambert-Eaton myasthenic syndrome.	PubMed search Amifampridine)	DrugBank search Amifampridine
Amiodarone	Cordarone, Pacerone, Nexterone	Frequently causes non-significant QT prolongaton. Rarely causes torsade de pointes. Low risk in patients without propensity for QT prolongation.	Class III Antiarrhythmic	Arrhythmia	A class III antiarrhythmic indicated for the treatment of ventricular premature beats, ventricular tachycardia and ventricular fibrillation.	PubMed search Amiodarone)	DrugBank search Amiodarone
Amisulpride	Barhemsys, Solian, Supitac, Soltus, Amitrex, Amazeo	Low to moderate risk (with IV use)	Antiemetic, Antipsychotic	Nausea and vomiting, postoperative	Dopamine D2 receptor antagonist used in the treatment of acute and chronic schizophrenia, and in the prevention and treatment of postoperative nausea and vomiting in adults.	PubMed search Amisulpride)	DrugBank search Amisulpride
Amitriptyline	Elavil, Tryptomer, Tryptizol, Laroxyl, Saroten, Sarotex Lentizol, Endep	Amitriptyline has been reported to induce long QT syndrome and Brugada syndrome (see PubMed link).	Antidepressant, Tricyclic	Depression	A tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety.	PubMed search Amitriptyline)	DrugBank search Amitriptyline
Amodiaquine		Data on amodiaquine are scarce, although transient effects on cardiac electrophysiology (QT interval prolongation and sinus bradycardia) have been observed (see PubMed link).	Antimalarial drug.	Antimalarial drug.	Antimalarial drug.	PubMed search Amodiaquine)	DrugBank search Amodiaquine
Amoxapine	Amoxapine	Amoxapine has been linked to cases of QT prolongation, acute heart failure, and sudden death (See PubMed links)			A tricyclic antidepressant used in the treatment of neurotic or reactive depressive disorders and endogenous or psychotic depression.	PubMed search Amoxapine)	DrugBank search Amoxapine
Amphetamine (Amfetamine)	Adderal-XR, Dexedrine, Dextroamp, Adderall, Adzenys, Dyanavel, Evekeo, Mydayis	Moderate risk.	CNS stimulant	ADHD	CNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).	PubMed search Amphetamine (Amfetamine))	DrugBank search Amphetamine (Amfetamine)
Amphotericin B	Fungilin, Fungizone, Abelcet, AmBisome, Fungisome, Amphocil, Amphotec	Several cases of QT prolongation and torsade de pointes described (see PubMed link).	Antifungal	Fungal infection	Antifungal used in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis.	PubMed search Amphotericin B)	DrugBank search Amphotericin B
Amsacrine (Acridinyl anisidide)	Amsidine	Classified as QT prolonging drug	Antineoplastic Agent	Cancer (Acute Lymphoblastic Leukemia)		PubMed search Amsacrine (Acridinyl anisidide)+AND+(%22QT%22+OR+Torsad*))	DrugBank search Amsacrine (Acridinyl anisidide)
Anagrelide	Agrylin, Xagrid	Low to moderate risk	Phosphodiesterase 3 inhibitor	Thrombocythemia	A platelet-reducing agent used to treat thrombocythemia, and its related complications, secondary to myeloproliferative neoplasms.	PubMed search Anagrelide)	DrugBank search Anagrelide
Anisodamine		Classified as QT prolonging drug			Anisodamine has been investigated for the treatment of Intestinal Diseases.	PubMed search Anisodamine)	DrugBank search Anisodamine
Antazoline		Classified as QT prolonging drug			An antihistamine agent used for the symptomatic treatment of nasal congestion and allergic conjunctivitis.	PubMed search Antazoline)	DrugBank search Antazoline
Apalutamide	Erleada	Classified as QT prolonging drug	nonsteroidal antiandrogen	Cancer (prostate)		PubMed search Apalutamide)	DrugBank search Apalutamide
Apomorphine	Apokyn, Ixense, Spontane, Uprima	Low to moderate risk	Dopamine agonist	Parkinson's disease	A morphine derivative D2 dopamine agonist used to treat hypomobile "off" episodes of advanced Parkinson's disease.	PubMed search Apomorphine)	DrugBank search Apomorphine
Aranidipine		Classified as QT prolonging drug			Aranidipine has been used for many years to treat angina pectoris and hypertension.	PubMed search Aranidipine)	DrugBank search Aranidipine
Arformoterol	Brovana	Low risk	Bronchodilator	Asthma, COPD	A beta-2 adrenergic agonist and bronchodilator used for long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.	PubMed search Arformoterol)	DrugBank search Arformoterol
Aripiprazole	Abilify, Aripiprex	Classified as QT prolonging drug	Antipsychotic, atypical	Schizophrenia, depression (adjunct)	An atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome.	PubMed search Aripiprazole)	DrugBank search Aripiprazole
Aripiprazole lauroxil		Classified as QT prolonging drug			An antipsychotic used to treat schizophrenia in adults.	PubMed search Aripiprazole lauroxil)	DrugBank search Aripiprazole lauroxil
Arsenic trioxide	Trisenox	High risk	Anti-cancer	Cancer (leukemia)	A chemotherapeutic agent used in the treatment of refractory or relapsed acute promyelocytic leukemia in patients with prior retinoid and anthracycline chemotherapy.	PubMed search Arsenic trioxide)	DrugBank search Arsenic trioxide
Artemether		Classified as QT prolonging drug			An antimalarial agent used in combination with lumefantrine for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum.	PubMed search Artemether)	DrugBank search Artemether
Artemether Lumefantrine	Coartem	Low risk	Anti-malarial	Marlaria		PubMed search Artemether Lumefantrine)	DrugBank search Artemether Lumefantrine
Artenimol / Piperaquine	Eurartesim	Moderate risk	Antimalarial	Malaria		PubMed search Artenimol / Piperaquine)	DrugBank search Artenimol / Piperaquine
Asenapine	Saphris, Sycrest	Low to moderate risk	Antipsychotic, atypical	Schizophrenia	An atypical antipsychotic used to treat patients with bipolar I disorder and patients with schizophrenia.	PubMed search Asenapine)	DrugBank search Asenapine
Astemizole	Hismanal	Classified as QT prolonging drug	Antihistamine	Allergic rhinitis	A second generation antihistamine used to treat allergy symptoms.	PubMed search Astemizole)	DrugBank search Astemizole
Atazanavir	Reyataz, Evotaz	Classified as QT prolonging drug	Antiviral	Viral infection (HIV/AIDS)	An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV.	PubMed search Atazanavir)	DrugBank search Atazanavir
Atomoxetine	Strattera	Low to moderate risk	CNS stimulant	ADHD	A selective norepinephrine reuptake inhibitor (SNRI) used in the management of Attention Deficit Hyperactivity Disorder (ADHD).	PubMed search Atomoxetine)	DrugBank search Atomoxetine
Azatadine		Classified as QT prolonging drug			An H1 receptor antagonist used to treat perennial and allergic rhinitis as well as eustachian tube congestion.	PubMed search Azatadine)	DrugBank search Azatadine
Azimilide		Classified as QT prolonging drug			Investigated for use/treatment in arrhythmia and atrial fibrillation.	PubMed search Azimilide)	DrugBank search Azimilide
Azithromycin	Zithromax, Zmax	Moderate risk	Antibiotic	Bacterial infection	A macrolide antibiotic used to treat a variety of bacterial infections.	PubMed search Azithromycin)	DrugBank search Azithromycin
Bedaquiline	Sirturo	High risk	Antibiotic	Tuberculosis, Multi-drug resistant	A diarylquinoline antimycobacterial used in combination with other antibacterials to treat pulmonary multidrug resistant tuberculosis (MDR-TB).	PubMed search Bedaquiline)	DrugBank search Bedaquiline
Bendamustine	Treanda, Treakisym, Ribomustin, Levact	Classified as QT prolonging drug	Anti-cancer	Cancer (Leukemia, lymphoma)		PubMed search Bendamustine)	DrugBank search Bendamustine
Bendroflumethiazide / Bendrofluazide	Aprinox, Corzide	Classified as QT prolonging drug	Diuretic, thiazide	Hypertension, diuresis		PubMed search Bendroflumethiazide / Bendrofluazide)	DrugBank search Bendroflumethiazide / Bendrofluazide
Benzatropine		Classified as QT prolonging drug			An anticholinergic drug used to treat Parkinson's disease (PD) and extrapyramidal symptoms, except tardive dyskinesia.	PubMed search Benzatropine)	DrugBank search Benzatropine
Benzphetamine	Didrex, Recede	Classified as QT prolonging drug		Obesity		PubMed search Benzphetamine)	DrugBank search Benzphetamine
Bepridil	Vascor	High risk	Antianginal	Angina Pectoris (heart pain)	For the treatment of hypertension, and chronic stable angina (classic effort-associated angina).	PubMed search Bepridil)	DrugBank search Bepridil
Berotralstat		Classified as QT prolonging drug			An inhibitor of plasma kallikrein used for prophylaxis of angioedema attacks in patients with hereditary angioedema.	PubMed search Berotralstat)	DrugBank search Berotralstat
Besifloxacin		Classified as QT prolonging drug			A fluoroquinolone antibiotic agent used for the treatment of bacterial conjunctivitis.	PubMed search Besifloxacin)	DrugBank search Besifloxacin
Betrixaban	Bevyxxa	Classified as QT prolonging drug	Anticoagulant	Anticoagulant		PubMed search Betrixaban)	DrugBank search Betrixaban
Bicalutamide	Casodex	Classified as QT prolonging drug	Anti-androgen	Cancer (prostate)		PubMed search Bicalutamide)	DrugBank search Bicalutamide
Bilastine	Blexten	Classified as QT prolonging drug	Antihistamines	Antihistamines		PubMed search Bilastine)	DrugBank search Bilastine
Bortezomib	Velcade, Bortecad	Classified as QT prolonging drug	Proteasome inhibitor	Cancer (multiple myeloma,lymphoma)	A proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies.	PubMed search Bortezomib)	DrugBank search Bortezomib
Bosutinib	Bosulif	Low risk	Anti-cancer	Cancer (leukemia)		PubMed search Bosutinib)	DrugBank search Bosutinib
Buclizine		Classified as QT prolonging drug			An antihistamine and antiemetic drug for the treatment of allergy symptoms and prevention of nausea and vomiting.	PubMed search Buclizine)	DrugBank search Buclizine
Bunaftine		Classified as QT prolonging drug			Not Annotated	PubMed search Bunaftine)	DrugBank search Bunaftine
Bupranolol		Classified as QT prolonging drug			Used to manage hypertension and tachycardia. Also used to treat glaucoma.	PubMed search Bupranolol)	DrugBank search Bupranolol
Buprenorphine	Butrans, Belbuca, Bunavail, Buprenex, Subutex, Suboxone, Zubsolv	Low risk	Opioid agonist	Narcotic dependence, pain		PubMed search Buprenorphine)	DrugBank search Buprenorphine
Buserelin		Classified as QT prolonging drug			A LHRH agonist used for the palliative treatment of hormone-dependent advanced carcinoma of the prostate gland in males and treatment of endometriosis in females.	PubMed search Buserelin)	DrugBank search Buserelin
Butriptyline		Classified as QT prolonging drug			Butriptyline is a tricyclic antidepressant which has been used in Europe since 1974. It is the isobutyl side chain homologue of amitriptyline.	PubMed search Butriptyline)	DrugBank search Butriptyline
Cabozantinib	Cometriq	Classified as QT prolonging drug	Anti-cancer	Cancer (renal cell)		PubMed search Cabozantinib)	DrugBank search Cabozantinib
Capecitabine	Xeloda	Moderate risk	Anti-cancer	Cancer (GI, Breast)		PubMed search Capecitabine)	DrugBank search Capecitabine
Carbetocin	Pabal, Lonactene, Duratocin	Moderate risk	uterotonic	Uterine atony		PubMed search Carbetocin)	DrugBank search Carbetocin
Cariporide		Classified as QT prolonging drug			Investigated for use/treatment in cardiac surgery.	PubMed search Cariporide)	DrugBank search Cariporide
Ceritinib	Zykadia	Moderate risk	Anti-cancer	Cancer (Lung)	An antineoplastic kinase inhibitor used to treat anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) in patients with inadequate clinical response or intolerance to crizotinib.	PubMed search Ceritinib)	DrugBank search Ceritinib
Cesium Chloride	Energy Catalyst	Classified as QT prolonging drug	toxin	Alternative therapy cancer		PubMed search Cesium Chloride)	DrugBank search Cesium Chloride
Chloral hydrate	Aquachloral, Novo-Chlorhydrate, Somnos, Noctec, Somnote	Classified as QT prolonging drug	Sedative	Sedation, insomnia		PubMed search Chloral hydrate)	DrugBank search Chloral hydrate
Chlorcyclizine		Classified as QT prolonging drug			Chlorcyclizine is a first generation phenylpiperazine class antihistamine used to treat urticaria, rhinitis, pruritus, and other allergy symptoms. Chlorcyclizine also has some local anesthetic, anticholinergic, and antiserotonergic properties, and can...	PubMed search Chlorcyclizine)	DrugBank search Chlorcyclizine
Chloroquine	Aralen	Moderate risk	Antimalarial	Malaria	An antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis.	PubMed search Chloroquine)	DrugBank search Chloroquine
Chlorpromazine	Thorazine, Largactil, Megaphen	High risk	Antipsychotic / Antiemetic	Psychosis, nausea, many others	A phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children.	PubMed search Chlorpromazine)	DrugBank search Chlorpromazine
Chlorprothixene	Truxal	Classified as QT prolonging drug	Antipsychotic	Schizophrenia		PubMed search Chlorprothixene)	DrugBank search Chlorprothixene
Cibenzoline		Classified as QT prolonging drug			Not Annotated	PubMed search Cibenzoline)	DrugBank search Cibenzoline
Cicletanine		Classified as QT prolonging drug			Cicletanine is under investigation for the treatment of Diabetes, Hypokalemia, Hyponatremia, and Arterial Hypertension.	PubMed search Cicletanine)	DrugBank search Cicletanine
Cilostazol	Pletal	Classified as QT prolonging drug	Phosphodiesterase 3 inhibitor	Intermittent claudication	An antiplatelet agent and vasodilator used for the symptomatic relief of intermittent claudication.	PubMed search Cilostazol)	DrugBank search Cilostazol
Cimetidine	Tagamet	Classified as QT prolonging drug	Antacid	Gastric hyperacidity, GERD		PubMed search Cimetidine)	DrugBank search Cimetidine
Cinoxacin		Classified as QT prolonging drug			For the treatment of initial and recurrent urinary tract infections in adults caused by the following susceptible microorganisms: Escherichia coli, Proteus mirabilis, Proteus vulgaris, Klebsiella species (including K. pneumoniae), and...	PubMed search Cinoxacin)	DrugBank search Cinoxacin
Ciprofloxacin	Cipro, Cipro-XR, Neofloxin	Low to moderate risk	Antibiotic	Bacterial infection	A second generation fluoroquinolone used to treat various susceptible bacterial infections.	PubMed search Ciprofloxacin)	DrugBank search Ciprofloxacin
Cisapride	Propulsid	High risk	GI stimulant	Increase GI motility	A medication used to treat heartburn associated with GERD.	PubMed search Cisapride)	DrugBank search Cisapride
Citalopram	Celexa, Cipramil	Moderate risk	Antidepressant, SSRI	Depression	A selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression.	PubMed search Citalopram)	DrugBank search Citalopram
Clarithromycin	Biaxin, Prevpac	Moderate risk	Antibiotic	Bacterial infection	A macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection.	PubMed search Clarithromycin)	DrugBank search Clarithromycin
Clemastine		Classified as QT prolonging drug			An antihistamine with sedative and anticholinergic effects used to treat the symptoms of allergic rhinitis.	PubMed search Clemastine)	DrugBank search Clemastine
Clofazimine	Lamprene	Moderate risk	Antibiotic	Leprosy		PubMed search Clofazimine)	DrugBank search Clofazimine
Clomipramine	Anafranil	Moderate risk	Antidepressant, Tricyclic	Depression	A tricyclic antidepressant used in the treatment of obsessive-compulsive disorder and disorders with an obsessive-compulsive component, such as depression, schizophrenia, and Tourette’s disorder.	PubMed search Clomipramine)	DrugBank search Clomipramine
Clotiapine	Clotiapine	Classified as QT prolonging drug				PubMed search Clotiapine)	DrugBank search Clotiapine
Clozapine	Clozaril, Fazaclo, Versacloz	Moderate risk	Antipsychotic, atypical	Schizophrenia	An antipsychotic drug used in treatment resistant schizophrenia and to decrease suicide risk in schizophrenic patients.	PubMed search Clozapine)	DrugBank search Clozapine
Cobimetinib	Cotellic	Classified as QT prolonging drug	Anti-cancer	Cancer (Melanoma)		PubMed search Cobimetinib)	DrugBank search Cobimetinib
Cocaine	Cocaine	Low to moderate risk with topical use	Local anesthetic	Anesthesia (topical)	An ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities.	PubMed search Cocaine)	DrugBank search Cocaine
Coumaphos		Classified as QT prolonging drug			This drug is a fat-soluble phosphorothioate agent that kills both insects and mites. It is non-volatile in nature and is well known by a variety of names as such a...	PubMed search Coumaphos)	DrugBank search Coumaphos
Crizotinib	Xalkori	Moderate risk	Anti-cancer	Cancer (Non-small cell lung cancer, metastatic)	A receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive.	PubMed search Crizotinib)	DrugBank search Crizotinib
CUDC-101		Classified as QT prolonging drug			CUDC-101 has been used in trials studying the treatment of Cancer, Tumors, Liver Cancer, Breast Cancer, and Gastric Cancer, among others.	PubMed search CUDC-101)	DrugBank search CUDC-101
CUDC-907		Classified as QT prolonging drug			CUDC-907 has been used in trials studying the treatment of Lymphoma, Solid Tumors, BREAST CANCER, Multiple Myeloma, and NUT Midline Carcinoma, among others.	PubMed search CUDC-907)	DrugBank search CUDC-907
Cyamemazine (Cyamepromazine)	Tercian	Classified as QT prolonging drug	Antipsychotic	Schizophrenia, sedation		PubMed search Cyamemazine (Cyamepromazine))	DrugBank search Cyamemazine (Cyamepromazine)
Cyclizine		Classified as QT prolonging drug			An antihistamine and antiemetic drug used for the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo.	PubMed search Cyclizine)	DrugBank search Cyclizine
Dabrafenib	Tafinlar	Moderate risk	Anti-cancer	Cancer (melanoma)	A kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.	PubMed search Dabrafenib)	DrugBank search Dabrafenib
Dasatinib	Sprycel	Moderate risk	Anti-cancer	Cancer (leukemia)	A tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy.	PubMed search Dasatinib)	DrugBank search Dasatinib
Degarelix	Firmagon, Ferring	Classified as QT prolonging drug	Anti-androgen	Cancer (prostate)	A GnRH receptor antagonist used in the management of advanced prostate cancer.	PubMed search Degarelix)	DrugBank search Degarelix
Delamanid	Deltyba	High risk	Antibiotic	Tuberculosis, Multi-drug resistant	An antibiotic used to treat multidrug resistant tuberculosis.	PubMed search Delamanid)	DrugBank search Delamanid
Desflurane		Classified as QT prolonging drug			A general inhalation anesthetic for inpatient and outpatient surgery in adults.	PubMed search Desflurane)	DrugBank search Desflurane
Desipramine	Pertofrane, Norpramine	Classified as QT prolonging drug	Antidepressant, Tricyclic	Depression	A tricyclic antidepressant used in the treatment of depression.	PubMed search Desipramine)	DrugBank search Desipramine
Deutetrabenazine	Austedo	Low to moderate risk	VMAT2 inhibitor	Huntington's disease		PubMed search Deutetrabenazine)	DrugBank search Deutetrabenazine
Dexbrompheniramine		Classified as QT prolonging drug			An antihistamine used to treat allergy symptoms including upper respiratory tract symptoms.	PubMed search Dexbrompheniramine)	DrugBank search Dexbrompheniramine
Dexmedetomidine	Dexdor, Igalmi, Precedex	Low risk	Anesthetic, general	Anesthesia		PubMed search Dexmedetomidine)	DrugBank search Dexmedetomidine
Dexmethylphenidate	Focalin, Focalin-XR, Attenade	Classified as QT prolonging drug	CNS stimulant	ADHD		PubMed search Dexmethylphenidate)	DrugBank search Dexmethylphenidate
Dextroamphetamine (dexamfetamine)	Dexedrine, dexamphetamine, dexamfetamine, (S)-(+)-amphetamine, Dextrostat, Dexedrine, Metamina, Attentin, Zenzedi, Procentra, Amfexa	Classified as QT prolonging drug	CNS stimulant	ADHD, obesity		PubMed search Dextroamphetamine (dexamfetamine))	DrugBank search Dextroamphetamine (dexamfetamine)
Dextromethorphan Quinidine	floxuridine	High risk	Unknown	Pseudobulbar affect		PubMed search Dextromethorphan Quinidine)	DrugBank search Dextromethorphan Quinidine
Dexverapamil		Classified as QT prolonging drug			Not Annotated	PubMed search Dexverapamil)	DrugBank search Dexverapamil
Dichlorvos		Classified as QT prolonging drug			Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products...	PubMed search Dichlorvos)	DrugBank search Dichlorvos
Diethylpropion (amfepramone)	Tenuate, Tepanil	Classified as QT prolonging drug	Sympathomimetic	Obesity		PubMed search Diethylpropion (amfepramone))	DrugBank search Diethylpropion (amfepramone)
Difloxacin		Classified as QT prolonging drug			Difloxacin is a synthetic fluoroquinolone used in veterinary. As an antibacterial, it presents a broad bactericidal spectrum and its effects are dependent on its concentration. However, it presents a reduced...	PubMed search Difloxacin)	DrugBank search Difloxacin
Diltiazem	Cardizem	Classified as QT prolonging drug	Calcium channel blocker	Hypertension		PubMed search Diltiazem)	DrugBank search Diltiazem
Diphenhydramine	Benadryl, Nytol, Unisom, Sominex, Dimedrol, Daedalon, Banophen	Classified as QT prolonging drug	Antihistamine	Allergic rhinitis, insomnia	A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.	PubMed search Diphenhydramine)	DrugBank search Diphenhydramine
Disopyramide	Norpace	Classified as QT prolonging drug	Antiarrhythmic	Arrhythmia	A class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias.	PubMed search Disopyramide)	DrugBank search Disopyramide
Dobutamine	Dobutrex	Classified as QT prolonging drug	Inotrope	Heart failure, shock (low blood pressure)		PubMed search Dobutamine)	DrugBank search Dobutamine
Dofetilide	Tikosyn	Classified as QT prolonging drug	Antiarrhythmic	Arrhythmia	A class III antiarrhythmic drug used for the maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter.	PubMed search Dofetilide)	DrugBank search Dofetilide
Dolasetron	Anzemet	Low to moderate risk	Antiemetic	Nausea, vomiting	An antinauseant and antiemetic used in chemotherapy and postoperatively.	PubMed search Dolasetron)	DrugBank search Dolasetron
Domperidone	Motilium, Motillium, Motinorm Costi, Nomit	Moderate risk	Antiemetic	Nausea, vomiting	A dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting.	PubMed search Domperidone)	DrugBank search Domperidone
Donepezil	Aricept	Low to moderate risk	Cholinesterase inhibitor	Dementia (Alzheimer's Disease)		PubMed search Donepezil)	DrugBank search Donepezil
Dopamine	Intropine	Classified as QT prolonging drug	Inotrope	Heart failure, shock (low blood pressure)		PubMed search Dopamine)	DrugBank search Dopamine
Doxepin	Sinequan, Silenor, Aponal, Adapine, Doxal, Deptran, Sinquan	Moderate risk	Antidepressant, Tricyclic	Depression	A psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia.	PubMed search Doxepin)	DrugBank search Doxepin
Doxylamine		Classified as QT prolonging drug			An antihistamine used to treat insomnia and allergy symptoms and is used with pyridoxine in the treatment of nausea and vomiting in pregnancy.	PubMed search Doxylamine)	DrugBank search Doxylamine
Dronedarone	Multaq	Classified as QT prolonging drug	Antiarrhythmic	Arrhythmia	An antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation.	PubMed search Dronedarone)	DrugBank search Dronedarone
Droperidol	Inapsine, Droleptan, Dridol, Xomolix	Moderate risk	Antipsychotic / Antiemetic	Anesthesia (adjunct), nausea	A butyrophenone derivative and dopamine antagonist used to prevent and treat postoperative nausea and vomiting.	PubMed search Droperidol)	DrugBank search Droperidol
Droxidopa	Northera	Classified as QT prolonging drug	Adrenergic pro-drug	Hypotension (Neurogenic orthostatic)		PubMed search Droxidopa)	DrugBank search Droxidopa
Echothiophate		Classified as QT prolonging drug			An acetylcholinesterase inhibitor used in ophthalmic preparations to increase the drainage of intraocular fluid; most commonly used for the treatment of glaucoma.	PubMed search Echothiophate)	DrugBank search Echothiophate
Efavirenz	Sustiva	Low to moderate risk	Antiviral	HIV/AIDS		PubMed search Efavirenz)	DrugBank search Efavirenz
Efonidipine		Classified as QT prolonging drug			For the treatment of hypertension.	PubMed search Efonidipine)	DrugBank search Efonidipine
Eliglustat	Cerdelga	Low to moderate risk	Glucosylceramide synthase inhibitor	Gaucher's disease	A glucosylceramide synthase used to treat type 1 Gaucher disease in patients who are CYP2D6 extensive, intermediate, or poor metabolizers.	PubMed search Eliglustat)	DrugBank search Eliglustat
Encainide		Classified as QT prolonging drug			A voltage-gated sodium channel blocker used for management of atrial or ventricular fibrillation, atrial flutter, and ventricular tachycardia, that is no longer used due to proarrhythmic adverse effects.	PubMed search Encainide)	DrugBank search Encainide
Encorafenib	Braftovi	Moderate risk	BRAF inhibitor	Cancer (Melanoma)		PubMed search Encorafenib)	DrugBank search Encorafenib
Enoxacin		Classified as QT prolonging drug			For the treatment of adults (≥18 years of age) with the following infections caused by susceptible strains of the designated microorganisms: (1) uncomplicated urethral or cervical gonorrhea due to Neisseria...	PubMed search Enoxacin)	DrugBank search Enoxacin
Entinostat		Classified as QT prolonging drug			Entinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers, and Normal Volunteers. Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic...	PubMed search Entinostat)	DrugBank search Entinostat
Entrectinib	Rozlytrek	Classified as QT prolonging drug	Anti-cancer	Cancer (Lung)	Entrectinib is indicated for the treatment of metastatic ROS1-positive non-small cell lung cancer in adults. Entrectinib is also indicated in adults and children over 12 years old for the treatment...	PubMed search Entrectinib)	DrugBank search Entrectinib
Eperisone	Eperisone	Classified as QT prolonging drug			An antispasmodic that functions through voltage-gated channel blockade, notably with little to no sedation, effective in relaxing skeletal muscles and vascular smooth muscles.	PubMed search Eperisone)	DrugBank search Eperisone
Ephedrine	Rynatuss, Broncholate	Classified as QT prolonging drug	Bronchodilator, decongestant	Allergic reaction, allergic rhinitis, asthma		PubMed search Ephedrine)	DrugBank search Ephedrine
Epinastine		Classified as QT prolonging drug			An H1 receptor antagonist used to prevent itching in allergic conjunctivitis.	PubMed search Epinastine)	DrugBank search Epinastine
Epinephrine (Adrenaline)	Primatene, Bronkaid	Classified as QT prolonging drug	Catecholamine, vasoconstrictor	Allergic reaction, anaphylaxis, cardiac arrest		PubMed search Epinephrine (Adrenaline))	DrugBank search Epinephrine (Adrenaline)
Epirubicin	Ellence, Pharmorubicin, Epirubicin Ebewe	Classified as QT prolonging drug	Anti-cancer	Cancer		PubMed search Epirubicin)	DrugBank search Epirubicin
Eribulin		Classified as QT prolonging drug			A microtubule inhibitor used to treat metastatic breast cancer and metastatic or unresectable liposarcoma.	PubMed search Eribulin)	DrugBank search Eribulin
Eribulin mesylate	Halaven	Low risk	Anti-cancer	Cancer (breast, metastatic)		PubMed search Eribulin mesylate)	DrugBank search Eribulin mesylate
Erlotinib		Classified as QT prolonging drug			An EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers.	PubMed search Erlotinib)	DrugBank search Erlotinib
Erythromycin	E.E.S., Robimycin, EMycin, Erymax, Ery-Tab, Eryc Ranbaxy, Erypar, Eryped, Erythrocin Stearate Filmtab, Erythrocot, E-Base, Erythroped, Ilosone, MY-E, Pediamycin, Abboticin, Abboticin-ES, Erycin, PCE Dispertab, Stiemycine, Acnasol, Tiloryth	Moderate risk	Antibiotic	Bacterial infection, increase GI motility	A macrolide antibiotic used to treat and prevent a variety of bacterial infections.	PubMed search Erythromycin)	DrugBank search Erythromycin
Escitalopram	Cipralex, Lexapro, Nexito, Anxiset-E, Exodus, Esto, Seroplex, Elicea, Lexamil, Lexam, Entact, Losita, Reposil, Animaxen, Esitalo, Lexamil	Moderate risk	Antidepressant, SSRI	Depression (major), anxiety disorders	A selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD).	PubMed search Escitalopram)	DrugBank search Escitalopram
Esomeprazole	Nexium, Nexum, Inexium	Classified as QT prolonging drug	Proton Pump Inhibitor	Gastric hyperacidity, GERD		PubMed search Esomeprazole)	DrugBank search Esomeprazole
Etelcalcetide	Parsabiv	Moderate risk	Calcium sensing receptor agonist	Secondary hyperparathyroidism		PubMed search Etelcalcetide)	DrugBank search Etelcalcetide
Ethosuximide		Classified as QT prolonging drug			An anticonvulsant used to treat petit mal seizures.	PubMed search Ethosuximide)	DrugBank search Ethosuximide
Ezogabine		Classified as QT prolonging drug			An antiepileptic agent used as an adjuvant treatment of partial-onset seizures.	PubMed search Ezogabine)	DrugBank search Ezogabine
Ezogabine (Retigabine)	Potiga, Trobalt	Low to moderate risk	Anticonvulsant	Seizures, Partial		PubMed search Ezogabine (Retigabine))	DrugBank search Ezogabine (Retigabine)
Famotidine	Pepcid, Fluxid, Quamatel	Classified as QT prolonging drug	H2-receptor antagonist	Gastric hyperacidity, GERD	A histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.	PubMed search Famotidine)	DrugBank search Famotidine
Famphur		Classified as QT prolonging drug			Not Annotated	PubMed search Famphur)	DrugBank search Famphur
Farnesyl diphosphate		Classified as QT prolonging drug			Not Available	PubMed search Farnesyl diphosphate)	DrugBank search Farnesyl diphosphate
Farnesyl thiopyrophosphate		Classified as QT prolonging drug			Not Available	PubMed search Farnesyl thiopyrophosphate)	DrugBank search Farnesyl thiopyrophosphate
Felbamate	Felbatol	Classified as QT prolonging drug	Anticonvulsant	Seizures	An anticonvulsant used to treat severe epilepsy.	PubMed search Felbamate)	DrugBank search Felbamate
Fendiline		Classified as QT prolonging drug			Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective.	PubMed search Fendiline)	DrugBank search Fendiline
Fenfluramine	Fintepla	Classified as QT prolonging drug	anti convulsant	Seizures		PubMed search Fenfluramine)	DrugBank search Fenfluramine
Fenoterol	Berotec, Berodual N	Classified as QT prolonging drug	bronchodilater	Asthma		PubMed search Fenoterol)	DrugBank search Fenoterol
Fenthion		Classified as QT prolonging drug			Fenthion is an organothiophosphate drug used as an insecticide, avicide, and acaricide. Its mode of action is explained by cholinesterase enzyme inhibition, which is similar to other organophosphates. Fenthion is...	PubMed search Fenthion)	DrugBank search Fenthion
Fexinidazole	Fexinidazole	Moderate risk	Antiparasitic	Antiparasitic		PubMed search Fexinidazole)	DrugBank search Fexinidazole
Fingolimod	Gilenya	Low to moderate risk	Sphingosine phospate receptor modulator	Multiple Sclerosis		PubMed search Fingolimod)	DrugBank search Fingolimod
Flecainide	Tambocor, Almarytm, Apocard, Ecrinal, Flécaine	Classified as QT prolonging drug	Antiarrhythmic	Arrhythmia	A class Ic antiarrhythmic agent used to manage atrial fibrillation and paroxysmal supraventricular tachycardias (PSVT).	PubMed search Flecainide)	DrugBank search Flecainide
Fleroxacin		Classified as QT prolonging drug			Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone.	PubMed search Fleroxacin)	DrugBank search Fleroxacin
Floxuridine	Floxuridine	Moderate risk	Anti-cancer	Anti-cancer		PubMed search Floxuridine)	DrugBank search Floxuridine
Fluconazole	Diflucan, Trican	Moderate risk	Antifungal	Fungal infection	A triazole antifungal used to treat various fungal infections including candidiasis.	PubMed search Fluconazole)	DrugBank search Fluconazole
Flumequine		Classified as QT prolonging drug			Flumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections.	PubMed search Flumequine)	DrugBank search Flumequine
Fluorouracil (5-FU)	Adrucil, Carac, Efudex, Efudix	Moderate risk (systemic use)	Anti-cancer	Cancer		PubMed search Fluorouracil (5-FU))	DrugBank search Fluorouracil (5-FU)
Fluoxetine	Prozac, Sarafem, Fontex	Low to moderate risk	Antidepressant, SSRI	Depression	A selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I.	PubMed search Fluoxetine)	DrugBank search Fluoxetine
Flupentixol	Depixol, Fluanxol	Moderate risk	Antipsychotic	Schizophrenia	A thioxanthene neuroleptic used to treat schizophrenia and depression.	PubMed search Flupentixol)	DrugBank search Flupentixol
Fluspirilene		Classified as QT prolonging drug			An antipsychotic agent used in the treatment of schizophrenia.	PubMed search Fluspirilene)	DrugBank search Fluspirilene
Fluticasone And Salmeterol	Advair, Seretide	Low risk	Bronchodilator	Asthma		PubMed search Fluticasone And Salmeterol)	DrugBank search Fluticasone And Salmeterol
Fluvoxamine	Faverin, Fevarin, Floxyfral, Dumyrox, Luvox	Classified as QT prolonging drug	Selective Serotonin Reuptake Inhibitor	Depression, Obsessive Compulsive Disorder		PubMed search Fluvoxamine)	DrugBank search Fluvoxamine
Formoterol	Foradil, Foradile, Oxeze, Oxis, Atock, Atimos, Atimos Modulite, Perforomist, Dulera, Symbicort, Vannair, Quikhale FB	Low risk	Bronchodilator	Asthma	An inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD.	PubMed search Formoterol)	DrugBank search Formoterol
Foscarnet	Foscavir	Moderate risk	Antiviral	HIV, CMV, HHV	An antiviral used to treat CMV, HIV, and HSV infections.	PubMed search Foscarnet)	DrugBank search Foscarnet
Fostemsavir	Rukobia	Low to moderate risk	Antiviral	HIV	An antiretroviral HIV-1 attachment inhibitor targeted against the gp120 subunit within the HIV-1 gp160 envelope glycoprotein.	PubMed search Fostemsavir)	DrugBank search Fostemsavir
Furosemide	Lasix, Fusid, Frumex, Lasilix	Classified as QT prolonging drug	Diuretic	Hypertension, diuresis		PubMed search Furosemide)	DrugBank search Furosemide
Gadobenate (Gadobenic acid)	Multihance	Moderate risk	MRI contrast	MRI imaging (liver imaging)		PubMed search Gadobenate (Gadobenic acid)+AND+(%22QT%22+OR+Torsad*))	DrugBank search Gadobenate (Gadobenic acid)
Gadobenic acid		Classified as QT prolonging drug			A gadolinium compound used as a contrast agent in MRIs.	PubMed search Gadobenic acid)	DrugBank search Gadobenic acid
Galantamine	Reminyl, Nivalin, Razadyne-ER, Lycoremine	Classified as QT prolonging drug	Cholinesterase inhibitor	Dementia (Alzheimer's Disease)	A cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease.	PubMed search Galantamine)	DrugBank search Galantamine
Gallopamil		Classified as QT prolonging drug			Gallopamil has been used in trials studying the treatment of Asthma.	PubMed search Gallopamil)	DrugBank search Gallopamil
Garenoxacin	Geninax	Classified as QT prolonging drug	Antibiotic	Bacterial infection	Investigated for use/treatment in bacterial infection.	PubMed search Garenoxacin)	DrugBank search Garenoxacin
Gatifloxacin	Tequin	Classified as QT prolonging drug	Antibiotic	Bacterial infection	A fourth generation fluoroquinolone used to treat a wide variety of infections in the body.	PubMed search Gatifloxacin)	DrugBank search Gatifloxacin
Gemifloxacin	Factive	Moderate risk	Antibiotic	Bacterial infection	A quinolone antibacterial agent used for the treatment of acute bacterial exacerbation of chronic bronchitis and mild to moderate community-acquired pneumonia caused by susceptible bacteria.	PubMed search Gemifloxacin)	DrugBank search Gemifloxacin
Geranylgeranyl diphosphate		Classified as QT prolonging drug			Not Available	PubMed search Geranylgeranyl diphosphate)	DrugBank search Geranylgeranyl diphosphate
Gilteritinib	Xospata	Moderate risk	Antineoplastic	Cancer (Acute Myeloid Leukemia)	An AXL receptor tyrosine kinase inhibitor used to treat relapsed or refractory acute myeloid leukemia.	PubMed search Gilteritinib)	DrugBank search Gilteritinib
Givinostat		Classified as QT prolonging drug			Givinostat has been used in trials studying the treatment of Polycythemia Vera, Juvenile Idiopathic Arthritis, Duchenne Muscular Dystrophy (DMD), Chronic Myeloproliferative Neoplasms, and Polyarticular Course Juvenile Idiopathic Arthritis.	PubMed search Givinostat)	DrugBank search Givinostat
Glasdegib	Daurismo	Low risk	Anti-cancer	Cancer (Acute myeloid leukemia)		PubMed search Glasdegib)	DrugBank search Glasdegib
Goserelin		Classified as QT prolonging drug			A synthetic analog of luteinizing hormone-releasing hormone used to treat breast cancer and prostate cancer by reducing secretion of gonadotropins from the pituitary.	PubMed search Goserelin)	DrugBank search Goserelin
Granisetron	Kytril, Sancuso, Granisol	Low to moderate risk	Antiemetic	Nausea, vomiting	A 5HT3 antagonist used to treat nausea and vomiting in cancer therapy and postoperatively.	PubMed search Granisetron)	DrugBank search Granisetron
Grepafloxacin	Raxar	Classified as QT prolonging drug	Antibiotic	Bacterial infection	A fluoroquinolone antibiotic used to treat various gram positive and gram negative bacterial infections.	PubMed search Grepafloxacin)	DrugBank search Grepafloxacin
Halofantrine	Halfan	Moderate risk	Antimalarial	Malaria	An antimalarial used for the treatment of severe malaria.	PubMed search Halofantrine)	DrugBank search Halofantrine
Haloperidol	Haldol, Aloperidin, Bioperidolo, Brotopon, Dozic, Duraperidol, Einalon S, Eukystol, Halosten, Keselan, Linton, Peluces, Serenace, Serenase, Sigaperidol	High risk with IV use. Moderate risk with PO use.	Antipsychotic	Schizophrenia, agitation	An antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium.	PubMed search Haloperidol)	DrugBank search Haloperidol
Histrelin		Classified as QT prolonging drug			A GnRH agonist found in subcutaneous implants used for the treatment of pediatric patients with central precocious puberty and the palliative treatment of advanced prostate cancer.	PubMed search Histrelin)	DrugBank search Histrelin
Hydrochlorothiazide	Apo-Hydro, Aquazide H, BP Zide, Dichlotride, Hydrodiuril, HydroSaluric, Microzide, Esidrex, Oretic	Classified as QT prolonging drug	Diuretic	Hypertension, diuresis		PubMed search Hydrochlorothiazide)	DrugBank search Hydrochlorothiazide
Hydrocodone Bitartrate ER	Hysingla™ ER, Zohydro ER	Classified as QT prolonging drug	Analgesic	Pain, severe		PubMed search Hydrocodone Bitartrate ER)	DrugBank search Hydrocodone Bitartrate ER
Hydroquinidine (Dihydroquinidine)	Serecor	High risk	Antiarrhythmic	Arrhythmia		PubMed search Hydroquinidine (Dihydroquinidine))	DrugBank search Hydroquinidine (Dihydroquinidine)
Hydroxychloroquine	Plaquenil, Quineprox	Low risk	Antimalarial, Anti-inflammatory	Malaria, SLE, rheumatoid arthritis	An antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus.	PubMed search Hydroxychloroquine)	DrugBank search Hydroxychloroquine
Hydroxyzine	Atarax, Vistaril, Aterax, Alamon, Durrax, Equipose, Masmoran, Orgatrax, Paxistil Quiess, Tran-Q, Tranquizine	Low to moderate risk	Antihistamine	Anxiety disorders, allergic reactions	An antihistamine used to treat anxiety and tension associated with psychoneuroses, as well as allergic conditions such as pruritus and chronic urticaria.	PubMed search Hydroxyzine)	DrugBank search Hydroxyzine
Hyoscyamine		Classified as QT prolonging drug			An anticholinergic indicated to treat functional gastrointestinal disorders, biliary and renal colic, and acute rhinitis.	PubMed search Hyoscyamine)	DrugBank search Hyoscyamine
Ibandronate		Classified as QT prolonging drug			A bisphosphonate used to treat osteoporosis in postmenopausal women.	PubMed search Ibandronate)	DrugBank search Ibandronate
Ibogaine	Ibogaine	Classified as QT prolonging drug	Psychedelic	Narcotic dependence, unproven efficacy		PubMed search Ibogaine)	DrugBank search Ibogaine
Ibutilide	Corvert	Classified as QT prolonging drug	Antiarrhythmic	Arrhythmia	A class III antiarrhythmic agent used to correct atrial fibrillation and atrial flutter, which can be considered as an alternative to cardioversion.	PubMed search Ibutilide)	DrugBank search Ibutilide
Iloperidone	Fanapt, Fanapta, Zomaril	Low to moderate risk	Antipsychotic, atypical	Schizophrenia	An atypical antipsychotic agent used for the acute treatment of schizophrenia in adults.	PubMed search Iloperidone)	DrugBank search Iloperidone
Imatinib	Gleevec, Glivec	Classified as QT prolonging drug	Anti-cancer	Cancer (Acute myeloid leukemia)	A tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.	PubMed search Imatinib)	DrugBank search Imatinib
Imipramine		Classified as QT prolonging drug			A tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis.	PubMed search Imipramine)	DrugBank search Imipramine
Imipramine (Melipramine)	Tofranil	Moderate risk	Antidepressant, Tricyclic	Depression		PubMed search Imipramine (Melipramine))	DrugBank search Imipramine (Melipramine)
Indacaterol	Arcapta Neohaler, Onbrez Breezhaler, Utibron	Low risk	Bronchodilator	Asthma, COPD	An inhaled long-acting beta-2 adrenergic agonist used to relax bronchial smooth muscle and improve symptoms and airflow obstruction caused by Chronic Obstructive Pulmonary Disease (COPD) and moderate to severe asthma.	PubMed search Indacaterol)	DrugBank search Indacaterol
Indapamide	Lozol, Natrilix, Insig	Classified as QT prolonging drug	Diuretic	Hypertension, diuresis	A thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure.	PubMed search Indapamide)	DrugBank search Indapamide
Indenolol		Classified as QT prolonging drug			Indenolol is a drug of the beta-adrenergic blocker class.	PubMed search Indenolol)	DrugBank search Indenolol
Inotersen		Classified as QT prolonging drug			An antisense oligonucleotide used to treat polyneuropathy of hereditary transthyretin-mediated amyloidosis.	PubMed search Inotersen)	DrugBank search Inotersen
Inotuzumab ozogamicin	Besponsa	Moderate risk	Anti-cancer	Cancer (acute lymphocytic leukemia}		PubMed search Inotuzumab ozogamicin)	DrugBank search Inotuzumab ozogamicin
Isoflurane		Classified as QT prolonging drug			An inhaled general anesthetic used in surgery.	PubMed search Isoflurane)	DrugBank search Isoflurane
Isoproterenol (isoprenaline)	Medihaler-Iso, Isuprel	Classified as QT prolonging drug	Bronchodilator	Allergic reaction		PubMed search Isoproterenol (isoprenaline))	DrugBank search Isoproterenol (isoprenaline)
Isradipine	Dynacirc	Classified as QT prolonging drug	Antihypertensive	Hypertension	A dihydropyridine calcium channel blocker used for the treatment of hypertension.	PubMed search Isradipine)	DrugBank search Isradipine
Itraconazole	Sporanox, Onmel	Low to moderate risk	Antifungal	Fungal infection	An antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis.	PubMed search Itraconazole)	DrugBank search Itraconazole
Ivabradine	Procoralan, Coralan, Corlentor, Coraxan, Ivabid, Bradia	Classified as QT prolonging drug	Antianginal	Angina Pectoris (heart pain)		PubMed search Ivabradine)	DrugBank search Ivabradine
Ivosidenib	Tibsovo	High risk	IDH1 inhibitor	Cancer (Acute myeloid leukemia)	An isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia and cholangiocarcinoma in adults with a susceptible IDH1 mutation.	PubMed search Ivosidenib)	DrugBank search Ivosidenib
Ketanserin	Sufrexal	Classified as QT prolonging drug	Antihypertensive	Hypertension		PubMed search Ketanserin)	DrugBank search Ketanserin
Ketoconazole	Nizoral, Sebizole, Ketomed, Keton	Low to moderate risk	Antifungal	Fungal infection	A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.	PubMed search Ketoconazole)	DrugBank search Ketoconazole
Lacidipine	Lacidipine	Classified as QT prolonging drug				PubMed search Lacidipine)	DrugBank search Lacidipine
Lansoprazole	Prevacid, Ogast	Classified as QT prolonging drug	Proton Pump Inhibitor	Gastric hyperacidity, GERD		PubMed search Lansoprazole)	DrugBank search Lansoprazole
Lapatinib	Tykerb, Tyverb	Low risk	Anti-cancer	Cancer (breast, metastatic)	An antineoplastic agent and tyrosine kinase inhibitor used for the treatment of advanced or metastatic HER-negative breast cancer in patients who received prior chemotherapeutic treatments.	PubMed search Lapatinib)	DrugBank search Lapatinib
Lefamulin	Xenleta	Classified as QT prolonging drug	Antibiotic	Community acquired pneumonia		PubMed search Lefamulin)	DrugBank search Lefamulin
Lenvatinib	Lenvima	High risk	Anti-cancer	Cancer (Thyroid)	A receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma.	PubMed search Lenvatinib)	DrugBank search Lenvatinib
Leuprolide		Classified as QT prolonging drug			A peptide-based GnRH receptor superagonist used for the palliative treatment of prostate cancer, uterine leiomyomata, endometriosis, and central precocious puberty.	PubMed search Leuprolide)	DrugBank search Leuprolide
Leuprolide / Leuprorelin	Lupron, Eligard, Viadur, Carcinil, Enanton, Leuplin, Lucrin, Procren, Prostap	Classified as QT prolonging drug	Anti-androgen	Cancer (prostate)		PubMed search Leuprolide / Leuprorelin)	DrugBank search Leuprolide / Leuprorelin
Levacetylmethadol		Classified as QT prolonging drug			For the treatment and management of opiate dependence. It is sometimes used to treat severe pain in terminal patients.	PubMed search Levacetylmethadol)	DrugBank search Levacetylmethadol
Levalbuterol (Levsalbutamol)	Xopenex, Levolin, Axazest	Low risk	Bronchodilator	Asthma		PubMed search Levalbuterol (Levsalbutamol))	DrugBank search Levalbuterol (Levsalbutamol)
Levetiracetam	Keppra	Classified as QT prolonging drug	Anti-seizure	Epilepsy		PubMed search Levetiracetam)	DrugBank search Levetiracetam
Levocetirizine		Classified as QT prolonging drug			An H1-receptor antagonist used to treat symptoms associated with chronic allergic rhinitis and uncomplicated cases of chronic idiopathic urticaria.	PubMed search Levocetirizine)	DrugBank search Levocetirizine
Levofloxacin	Levaquin, Tavanic	Moderate risk	Antibiotic	Bacterial infection	A fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague.	PubMed search Levofloxacin)	DrugBank search Levofloxacin
Levoketoconazole	Recorlev	High risk	CYP450 inhibitor	Cushing's disease	One of two enantiomeric forms of racemic ketoconazole that strongly inhibits multiple steroidogenic enzymes and is used for the symptomatic treatment of endogenous Cushing's syndrome.	PubMed search Levoketoconazole)	DrugBank search Levoketoconazole
Levomenthol		Classified as QT prolonging drug			An organic compound used to treat mild to moderate muscle and joint pain.	PubMed search Levomenthol)	DrugBank search Levomenthol
Levomepromazine (Methotrimeprazine)	Nosinan, Nozinan, Levoprome	Classified as QT prolonging drug	Antipsychotic	Schizophrenia		PubMed search Levomepromazine (Methotrimeprazine))	DrugBank search Levomepromazine (Methotrimeprazine)
Levomethadone	Levomethadone	Classified as QT prolonging drug	Opioid	Opiate withdrawal syndrome		PubMed search Levomethadone+AND+(%22QT%22+OR+Torsad*))	DrugBank search Levomethadone
Levomethadyl acetate	Orlaam	Classified as QT prolonging drug	Opioid agonist	Narcotic dependence		PubMed search Levomethadyl acetate)	DrugBank search Levomethadyl acetate
Levomethamphetamine (Levmetamfetamine)	Sinu Inhaler, Vapor Inhaler	Classified as QT prolonging drug	Sympathomimetic	Sinus Congestion		PubMed search Levomethamphetamine (Levmetamfetamine))
Levosulpiride	Lesuride, Levazeo, Enliva	Classified as QT prolonging drug	Antipsychotic	Schizophrenia		PubMed search Levosulpiride)	DrugBank search Levosulpiride
Lidoflazine		Classified as QT prolonging drug			Not Annotated	PubMed search Lidoflazine)	DrugBank search Lidoflazine
Lisdexamfetamine	Vyvanse	Classified as QT prolonging drug	CNS stimulant	ADHD		PubMed search Lisdexamfetamine)	DrugBank search Lisdexamfetamine
Lithium	Eskalith, Lithobid	Classified as QT prolonging drug	Antimanic	Bipolar disorder		PubMed search Lithium)	DrugBank search Lithium
Lithium cation		Classified as QT prolonging drug			A drug used for the management of bipolar disorder and other psychiatric conditions.	PubMed search Lithium cation)	DrugBank search Lithium cation
Lithium citrate		Classified as QT prolonging drug			Lithium is used as a mood stabilizer, and is used for treatment of depression and mania. It is often used in bipolar disorder treatment.	PubMed search Lithium citrate)	DrugBank search Lithium citrate
Lofexidine	Lucemyra	Moderate risk	Alpha-2-adrenergic agonist, central	Opioid withdrawal syndrome		PubMed search Lofexidine)	DrugBank search Lofexidine
Lomefloxacin		Classified as QT prolonging drug			A fluoroquinolone used to prevent and treat a wide variety of infections in the body.	PubMed search Lomefloxacin)	DrugBank search Lomefloxacin
Loperamide	Imodium	Risk if overdosed	Opioid agonist	Diarrhea		PubMed search Loperamide)	DrugBank search Loperamide
Lopinavir		Classified as QT prolonging drug			An HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection.	PubMed search Lopinavir)	DrugBank search Lopinavir
Lopinavir/Ritonavir	Kaletra, Aluvia	Low to moderate risk	Antiviral	HIV/AIDS		PubMed search Lopinavir/Ritonavir)	DrugBank search Lopinavir/Ritonavir
Lorajmine		Classified as QT prolonging drug			Not Annotated	PubMed search Lorajmine)	DrugBank search Lorajmine
Lorcainide		Classified as QT prolonging drug			Not Annotated	PubMed search Lorcainide)	DrugBank search Lorcainide
Losartan		Classified as QT prolonging drug			An angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke.	PubMed search Losartan)	DrugBank search Losartan
Lumateperone	Caplyta	Classified as QT prolonging drug	Antipsychotic, atypical	Schizophrenia		PubMed search Lumateperone)	DrugBank search Lumateperone
Lumefantrine		Classified as QT prolonging drug			An antimalarial agent used in combination with artemether for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum.	PubMed search Lumefantrine)	DrugBank search Lumefantrine
Lurasidone	Latuda	Classified as QT prolonging drug	Antipsychotic, atypical	Schizophrenia, biopolar disorder and others	An atypical antipsychotic used to treat schizophrenia and depressive episodes associated with bipolar I disorder.	PubMed search Lurasidone)	DrugBank search Lurasidone
Maprotiline	Ludiomil	Classified as QT prolonging drug	Anti-depressant, Tetracyclic	Depression	A tetracyclic antidepressant used to treat depressive illness, major depressive disorder, bipolar disorder, and anxiety associated with depression.	PubMed search Maprotiline)	DrugBank search Maprotiline
Mefloquine		Classified as QT prolonging drug			An antimalarial agent used in the prophylaxis and treatment of malaria caused by Plasmodium falciparum and Plasmodium vivax.	PubMed search Mefloquine)	DrugBank search Mefloquine
Meglumine antimoniate	Glucantime	Moderate risk	Antiparasitic	Leishmaniasis		PubMed search Meglumine antimoniate)	DrugBank search Meglumine antimoniate
Melperone	Bunil, Buronil, Eunerpan	Classified as QT prolonging drug	Antipsychotic, atypical	Schizophrenia	An atypical butyrophenone antipsychotic used to treat sleep disorders, confusion, and psychomotor dysfunction associated with geriatric, psychiatric, and alcohol-dependent patients.	PubMed search Melperone)	DrugBank search Melperone
Mepyramine		Classified as QT prolonging drug			An antihistamine agent used for the symptomatic treatment of allergy, hypersensitivity reactions, and pruritic skin disorders.	PubMed search Mepyramine)	DrugBank search Mepyramine
Mequitazine		Classified as QT prolonging drug			For the treatment of Hay fever, urticaria (hives) and allergic rhinitis	PubMed search Mequitazine)	DrugBank search Mequitazine
Mesoridazine	Serentil	Classified as QT prolonging drug	Antipsychotic	Schizophrenia	A phenothiazine antipsychotic used to treat schizophrenia, organic brain disorders, alcoholism, and psychoneuroses.	PubMed search Mesoridazine)	DrugBank search Mesoridazine
Metaproterenol (Orciprenaline)	Metaprel, Alupent	Classified as QT prolonging drug	Bronchodilator	Asthma		PubMed search Metaproterenol (Orciprenaline))	DrugBank search Metaproterenol (Orciprenaline)
Methadone	Dolophine, Symoron, Amidone, Methadose, Physeptone, Heptadon	High risk	Opioid agonist	Narcotic dependence, pain	An opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction.	PubMed search Methadone)	DrugBank search Methadone
Methamphetamine (Metamfetamine)	Desoxyn, Pervitin, Anadrex, Methedrine, Syndrox	Classified as QT prolonging drug	CNS stimulant	Obesity, ADHD		PubMed search Methamphetamine (Metamfetamine))	DrugBank search Methamphetamine (Metamfetamine)
Methotrimeprazine		Classified as QT prolonging drug			A phenothiazine used in the management of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder.	PubMed search Methotrimeprazine)	DrugBank search Methotrimeprazine
Methylphenidate	Ritalin, Concerta, Focalin, Daytrana, Methylin, Metadate CD	Classified as QT prolonging drug	CNS stimulant	ADHD		PubMed search Methylphenidate)	DrugBank search Methylphenidate
Metoclopramide	Reglan, Gimoti, Afipran, Maxolon, Cerucal, Clopamon, Clopra, Maxeran, Maxolon, Metozolv, Plasil, Pramin, Primperan, Perinorm	Low to moderate risk	Antiemetic	Nausea, vomiting	An antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.	PubMed search Metoclopramide)	DrugBank search Metoclopramide
Metolazone	Zytanix, Zaroxolyn, Mykrox	Classified as QT prolonging drug	Diuretic	Hypertension, diuresis		PubMed search Metolazone)	DrugBank search Metolazone
Metronidazole	Flagyl, Helidac	Low to moderate risk	Antibiotic	Trichomoniasis, amebiasis, bacterial infection	A nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.	PubMed search Metronidazole)	DrugBank search Metronidazole
Mianserin	Tolvon	Classified as QT prolonging drug	Anti-depressant	Depression		PubMed search Mianserin)	DrugBank search Mianserin
Mibefradil		Classified as QT prolonging drug			For the treatment of angina and high blood pressure.	PubMed search Mibefradil)	DrugBank search Mibefradil
Midodrine	ProAmatine, Amatine, Gutron	Classified as QT prolonging drug	Vasoconstrictor	Hypotension		PubMed search Midodrine)	DrugBank search Midodrine
Midostaurin	Rydapt	Moderate risk	Anti-cancer	Cancer (Acute myeloid leukemia)		PubMed search Midostaurin)	DrugBank search Midostaurin
Mifepristone	Korlym, Mifeprex	Low to moderate risk	Progesterone antagonist	Pregnancy termination	A cortisol receptor blocker used to treat Cushing's syndrome, and to terminate pregnancies up to 70 days gestation.	PubMed search Mifepristone)	DrugBank search Mifepristone
Mirabegron	Myrbetriq	Classified as QT prolonging drug	Beta3 adrenergic antagonist	Bladder spasm	A beta-3 adrenergic agonist used to treat overactive bladder and neurogenic detrusor overactivity.	PubMed search Mirabegron)	DrugBank search Mirabegron
Mirtazapine	Remeron	Low risk	Antidepressant, Tetracyclic	Depression	A tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite.	PubMed search Mirtazapine)	DrugBank search Mirtazapine
Mobocertinib	Exkivity	High risk	Tyrosine kinase inhibitor	Cancer (Lung)	An oral kinase inhibitor targeted against EGFR and used in the treatment of NSCLC with EGFR exon 20 insertion mutations.	PubMed search Mobocertinib)	DrugBank search Mobocertinib
Mocetinostat		Classified as QT prolonging drug			Mocetinostat has been used in trials studying the treatment of Lymphoma, Urothelial Carcinoma, Relapsed and Refractory, Myelodysplastic Syndrome, and Metastatic Leiomyosarcoma, among others.	PubMed search Mocetinostat)	DrugBank search Mocetinostat
Moexipril		Classified as QT prolonging drug			An angiotensin converting enzyme inhibitor prodrug used to treat hypertension.	PubMed search Moexipril)	DrugBank search Moexipril
Moricizine		Classified as QT prolonging drug			An antiarrhythmic used to treat arrhythmias.	PubMed search Moricizine)	DrugBank search Moricizine
Moxifloxacin	Avelox, Avalox, Avelon	Moderate risk	Antibiotic	Bacterial infection	A fluoroquinolone antibiotic used to treat various bacterial infections.	PubMed search Moxifloxacin)	DrugBank search Moxifloxacin
Necitumumab	Portrazza	Classified as QT prolonging drug	anti-cancer	Cancer (Lung)		PubMed search Necitumumab)	DrugBank search Necitumumab
Nelfinavir	Viracept	Classified as QT prolonging drug	Antiviral	Viral infection (HIV/AIDS)	A viral protease inhibitor used in the treatment of HIV infection.	PubMed search Nelfinavir)	DrugBank search Nelfinavir
Nemonoxacin		Classified as QT prolonging drug			Investigated for use/treatment in bacterial infection and pneumonia.	PubMed search Nemonoxacin)	DrugBank search Nemonoxacin
Nicardipine	Cardene	Classified as QT prolonging drug	Antihypertensive	Hypertension	A calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina.	PubMed search Nicardipine)	DrugBank search Nicardipine
Nifekalant	Shinbit	Classified as QT prolonging drug	Antiarrhythmic	Arrhythmia		PubMed search Nifekalant)	DrugBank search Nifekalant
Niguldipine		Classified as QT prolonging drug			Niguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties.	PubMed search Niguldipine)	DrugBank search Niguldipine
Nilotinib	Tasigna	Moderate risk	Anti-cancer	Cancer (leukemia)	A kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib.	PubMed search Nilotinib)	DrugBank search Nilotinib
Nizofenone		Classified as QT prolonging drug			Not Annotated	PubMed search Nizofenone)	DrugBank search Nizofenone
Norepinephrine	Levophed	Classified as QT prolonging drug	Vasconstrictor, Inotrope	Heart failure, shock (low blood pressure)		PubMed search Norepinephrine)	DrugBank search Norepinephrine
Norfloxacin	Noroxin, Ambigram	Low to moderate risk	Antibiotic	Bacterial infection	A broad-spectrum fluoroquinolone antibiotic with variable activity against gram-positive and gram-negative bacteria. Typically reserved for the treatment of UTIs due to accumulation in the urine.	PubMed search Norfloxacin)	DrugBank search Norfloxacin
Nortriptyline	Pamelor, Sensoval, Aventyl, Norpress, Allegron, Noritren, Nortrilen	Classified as QT prolonging drug	Antidepressant, Tricyclic	Depression	A tricyclic antidepressant used in the treatment of depression.	PubMed search Nortriptyline)	DrugBank search Nortriptyline
Nusinersen	Spinraza	Classified as QT prolonging drug	Antisense oligonucleotide	Spinal Muscular Atrophy		PubMed search Nusinersen)	DrugBank search Nusinersen
Octreotide		Classified as QT prolonging drug			A peptide drug used to treat acromegaly as well as diarrhea associated with metastatic carcinoid tumors and vasoactive intestinal peptide secreting tumors.	PubMed search Octreotide)	DrugBank search Octreotide
Ofloxacin	Floxin	Low to moderate risk	Antibiotic	Bacterial infection	An antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract.	PubMed search Ofloxacin)	DrugBank search Ofloxacin
Olanzapine	Zyprexa, Zydis, Relprevv	Moderate risk	Antipsychotic, atypical	Schizophrenia, bipolar disorder	An antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders.	PubMed search Olanzapine)	DrugBank search Olanzapine
Oliceridine	Olinvyk	Classified as QT prolonging drug	analgesia	pain		PubMed search Oliceridine)	DrugBank search Oliceridine
Olodaterol	Striverdi Respimat	Low risk	Bronchodilator	Asthma	A long-acting beta2-adrenergic agonist used in the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.	PubMed search Olodaterol)	DrugBank search Olodaterol
Omeprazole	Losec, Prilosec, Zegerid, Mopral	Classified as QT prolonging drug	Proton Pump Inhibitor	Gastric hyperacidity, GERD		PubMed search Omeprazole)	DrugBank search Omeprazole
Ondansetron	Zofran, Anset, Ondemet, Zuplenz, Emetron, Ondavell, Emeset, Ondisolv, Setronax	Moderate risk with IV use. Low risk with PO use.	Antiemetic	Nausea, vomiting	A serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting in cancer chemotherapy and postoperatively.	PubMed search Ondansetron)	DrugBank search Ondansetron
Orbifloxacin		Classified as QT prolonging drug			Orbifloxacin is a fluoroquinolone antibiotic. It is marketed by Schering-Plough Animal Health and approved for certain infections in dogs.	PubMed search Orbifloxacin)	DrugBank search Orbifloxacin
Osilodrostat	Isturisa	Classified as QT prolonging drug	Aldosterone synthase inhibitor	Cushing's Disease		PubMed search Osilodrostat)	DrugBank search Osilodrostat
Osimertinib	Tagrisso	Moderate risk	Anti-cancer	Cancer (EGFR pos. NSC Lung cancer)		PubMed search Osimertinib)	DrugBank search Osimertinib
Oxaliplatin	Eloxatin	Low risk	Anti-cancer	Cancer	A platinum based chemotherapy agent used to treat carcinoma of the colon or rectum or stage III colon cancer.	PubMed search Oxaliplatin)	DrugBank search Oxaliplatin
Oxatomide		Classified as QT prolonging drug			An antihistamine indicated in the treatment and prevention of allergic symptoms.	PubMed search Oxatomide)	DrugBank search Oxatomide
Oxolinic acid		Classified as QT prolonging drug			Not Annotated	PubMed search Oxolinic acid)	DrugBank search Oxolinic acid
Oxymetazoline	Afrin, Otrivin, Vicks Sinex, Zicam	Classified as QT prolonging drug	Decongestant	Allergic rhinitis		PubMed search Oxymetazoline+AND+(%22QT%22+OR+Torsad*))	DrugBank search Oxymetazoline
Oxytocin	Pitocin, Syntocinon	Moderate risk	Oxytocic	Labor stimulation	A recombinant hormone used to induce or strengthen uterine contractions in pregnant women to aid in labor and delivery or to control postpartum bleeding.	PubMed search Oxytocin)	DrugBank search Oxytocin
Ozanimod	Zeposia	Low to moderate risk	Immunomodulation	Multiple Sclerosis		PubMed search Ozanimod)	DrugBank search Ozanimod
Pacritinib	Vonjo	Low risk	Kinase (JAK2) inhibitor	Myelofibrosis		PubMed search Pacritinib)	DrugBank search Pacritinib
Paliperidone	Invega, Xepilon	Low to moderate risk	Antipsychotic, atypical	Schizophrenia	An atypical antipsychotic used in the treatment of schizophrenia and other schizoaffective or delusional disorders.	PubMed search Paliperidone)	DrugBank search Paliperidone
Palonosetron	Aloxi	Classified as QT prolonging drug	Antiemetic	Nausea, vomiting		PubMed search Palonosetron)	DrugBank search Palonosetron
Panobinostat	Farydak	Low risk	Histone deacetylase inhibitor	Cancer, Multiple myeloma	A non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents.	PubMed search Panobinostat)	DrugBank search Panobinostat
Pantoprazole	Protonix, Inipomp, Eupantol	Classified as QT prolonging drug	Proton Pump Inhibitor	Gastric hyperacidity, GERD		PubMed search Pantoprazole)	DrugBank search Pantoprazole
Papaverine	Papaverine	High risk (intracoronary administration)	Vasodilator, Coronary	Diagnostic adjunct	An alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms".	PubMed search Papaverine)	DrugBank search Papaverine
Paroxetine	Paxil, Aropax, Pexeva, Seroxat, Sereupin, Seroxat, Deroxat	Classified as QT prolonging drug	Antidepressant, SSRI	Depression		PubMed search Paroxetine)	DrugBank search Paroxetine
Pasireotide	Signifor	Low to moderate risk	Somatostatin analog	Cushing's Disease	A somatostatin analog used in the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery is not appropriate.	PubMed search Pasireotide)	DrugBank search Pasireotide
Pazopanib	Votrient	Moderate risk	Anti-cancer	Cancer (renal cell, sarcoma)	An antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy.	PubMed search Pazopanib)	DrugBank search Pazopanib
Pazufloxacin		Classified as QT prolonging drug			Pazufloxacin is under investigation in clinical trial NCT02592096 (Pazufloxacin Mesilate Ear Drops Clinical Trial Protocol).	PubMed search Pazufloxacin)	DrugBank search Pazufloxacin
Pefloxacin		Classified as QT prolonging drug			An antibiotic used to treat a variety of bacterial infections.	PubMed search Pefloxacin)	DrugBank search Pefloxacin
Penfluridol		Classified as QT prolonging drug			Not Annotated	PubMed search Penfluridol)	DrugBank search Penfluridol
Pentamidine	Pentam	Moderate risk	Antifungal	Fungal infection (Pneumocystis pneumonia)	An antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV.	PubMed search Pentamidine)	DrugBank search Pentamidine
Perflutren		Classified as QT prolonging drug			A diagnostic medication to improve contrast during echocardiograms.	PubMed search Perflutren)	DrugBank search Perflutren
Perflutren lipid microspheres	Definity, Optison	Classified as QT prolonging drug	Imaging contrast agent	Diagnostic adjunct		PubMed search Perflutren lipid microspheres)	DrugBank search Perflutren lipid microspheres
Perhexiline		Classified as QT prolonging drug			For the management of severe angina pectoris.	PubMed search Perhexiline)	DrugBank search Perhexiline
Periciazine	Periciazine	Low to moderate risk	Antipsychotic, atypical	Schizophrenia		PubMed search Periciazine)	DrugBank search Periciazine
Perphenazine	Trilafon, Etrafon/Triavil, Decentan	Classified as QT prolonging drug	Antipsychotic	Schizophrenia		PubMed search Perphenazine)	DrugBank search Perphenazine
Phendimetrazine	Bontril, Adipost, Anorex, Plegine, Appecon, Melfiat, Obezine, Phendiet, Prelu-2, Statobex	Classified as QT prolonging drug		Obesity		PubMed search Phendimetrazine)	DrugBank search Phendimetrazine
Pheniramine		Classified as QT prolonging drug			An antihistamine used to treat allergic rhinitis and pruritus.	PubMed search Pheniramine)	DrugBank search Pheniramine
Phentermine	Adipex P, Adiphene, Anoxine-AM, Ionamin, Duromine, Metermine, Miraprontv, Obephen, Obermine, Obestin-30, Phentremine, Phentrol, Phenterex, Phentromin, Pro-Fast SA, Redusa, Panbesy, Obenix, Oby-Trim, Teramine, Zantryl, Sinpet, Supremin, Suprenza, Umine, Weltmine	Classified as QT prolonging drug	Appetite suppressant	Obesity		PubMed search Phentermine)	DrugBank search Phentermine
Phenylephrine	Neosynephrine	Classified as QT prolonging drug	Vasoconstrictor	Shock (low blood pressure), allergic rhinitis, asthma		PubMed search Phenylephrine)	DrugBank search Phenylephrine
Phenylpropanolamine	Acutrim, Dexatrim	Classified as QT prolonging drug	Appetite suppressant	Obesity		PubMed search Phenylpropanolamine)	DrugBank search Phenylpropanolamine
Phosmet		Classified as QT prolonging drug			Phosmet is a phthalimide-derived organophosphate. It is a non-specific insecticide. It is mainly used on apple trees to control codling moths. It is also used on other fruit crops, ornamentals,...	PubMed search Phosmet)	DrugBank search Phosmet
Pilsicainide	Sunrythm	Classified as QT prolonging drug	Anti-arrhythmic	Arrhythmia	Pilsicainide has been investigated for the treatment of Paroxysmal Atrial Fibrillation.	PubMed search Pilsicainide)	DrugBank search Pilsicainide
Pimavanserin	Nuplazid	Low to moderate risk	Antipsychotic, atypical	Psychosis, Parkinson's Disease		PubMed search Pimavanserin)	DrugBank search Pimavanserin
Pimozide	Orap	Moderate risk	Antipsychotic	Psychosis, Tourette's Disorder	An antipsychotic used to manage debilitating motor and phonic tics in patients with Tourette's Disorder.	PubMed search Pimozide)	DrugBank search Pimozide
Pipamperone	Dipiperon, Propitan, Dipiperal, Piperonil, Piperonyl	Classified as QT prolonging drug	Antipsychotic	Schizophrenia		PubMed search Pipamperone)	DrugBank search Pipamperone
Piperacillin / Tazobactam	Tazosyn, Zosyn, PipTaz	Classified as QT prolonging drug	Antibiotic	Bacterial infection		PubMed search Piperacillin / Tazobactam)	DrugBank search Piperacillin / Tazobactam
Piromidic acid		Classified as QT prolonging drug			Not Annotated	PubMed search Piromidic acid)	DrugBank search Piromidic acid
Pitolisant		Classified as QT prolonging drug			An antagonist and inverse agonist at the histamine H3 receptor that is used to treat narcolepsy in adults.	PubMed search Pitolisant)	DrugBank search Pitolisant
Pitolisant (Tiprolisant)	Wakix	Classified as QT prolonging drug	Histamine 3 antagonist/inverse agonist	Narcolepsy		PubMed search Pitolisant (Tiprolisant))	DrugBank search Pitolisant (Tiprolisant)
Ponesimod	Ponvory	Low to moderate risk	Sphingosine 1-phosphate receptor modulator	Multiple Sclerosis		PubMed search Ponesimod)	DrugBank search Ponesimod
Posaconazole	Noxafil, Posamol	Classified as QT prolonging drug	Antifungal	Fungal infection	A triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.	PubMed search Posaconazole)	DrugBank search Posaconazole
Pracinostat		Classified as QT prolonging drug			For the treatment of various forms of cancer.	PubMed search Pracinostat)	DrugBank search Pracinostat
Prajmaline		Classified as QT prolonging drug			Not Annotated	PubMed search Prajmaline)	DrugBank search Prajmaline
Pregabalin		Classified as QT prolonging drug			An anticonvulsant drug used to treat neuropathic pain conditions and fibromyalgia, and for the treatment of partial onset seizures in combination with other anticonvulsants.	PubMed search Pregabalin)	DrugBank search Pregabalin
Prenylamine		Classified as QT prolonging drug			Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.	PubMed search Prenylamine)	DrugBank search Prenylamine
Pretomanid	Pretomanid	Classified as QT prolonging drug	Antitubercular	Tuberculosis, extensively drug resistant		PubMed search Pretomanid)	DrugBank search Pretomanid
Primaquine		Classified as QT prolonging drug			An antimalarial indicated to prevent relapse of vivax malaria.	PubMed search Primaquine)	DrugBank search Primaquine
Primaquine phosphate	Neo-Quipenyl, Primachin	Classified as QT prolonging drug	Antimalarial	Malaria		PubMed search Primaquine phosphate)	DrugBank search Primaquine phosphate
Probucol	Lorelco	Moderate risk	Antilipemic	Hypercholesterolemia	Used to lower LDL and HDL cholesterol.	PubMed search Probucol)	DrugBank search Probucol
Procainamide	Pronestyl, Procan	Classified as QT prolonging drug	Antiarrhythmic	Arrhythmia	A medication used to treat life threatening ventricular arrhythmias.	PubMed search Procainamide)	DrugBank search Procainamide
Promazine		Classified as QT prolonging drug			A phenothiazine used to manage schizophrenia.	PubMed search Promazine)	DrugBank search Promazine
Promethazine	Phenergan	Classified as QT prolonging drug	Antipsychotic / Antiemetic	Nausea, vomiting	A first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness.	PubMed search Promethazine)	DrugBank search Promethazine
Propafenone	Rythmol SR, Rytmonorm	Classified as QT prolonging drug	Sodium channel blocker	Arrhythmia	A Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias.	PubMed search Propafenone)	DrugBank search Propafenone
Propofol	Diprivan, Propoven	Moderate risk	Anesthetic, general	Anesthesia	A medication used in general anesthesia and for sedation.	PubMed search Propofol)	DrugBank search Propofol
Prothipendyl	Dominal, Largophren, Timoval, Timovan, Tumovan	Classified as QT prolonging drug	Antipsychotic	Schizophrenia		PubMed search Prothipendyl)	DrugBank search Prothipendyl
Protriptyline		Classified as QT prolonging drug			A tricyclic antidepressant that is indicated in the treatment of depression only under close clinical supervision.	PubMed search Protriptyline)	DrugBank search Protriptyline
Pseudoephedrine	PediaCare, Sudafed	Classified as QT prolonging drug	Decongestant	Allergic reaction, allergic rhinitis, asthma		PubMed search Pseudoephedrine)	DrugBank search Pseudoephedrine
Quetiapine	Seroquel	Moderate risk	Antipsychotic, atypical	Schizophrenia	A psychotropic agent used for the management of bipolar disorder, schizophrenia, and major depressive disorder.	PubMed search Quetiapine)	DrugBank search Quetiapine
Quinidine	Quinaglute, Duraquin, Quinact, Quinidex, Cin-Quin, Quinora	High risk	Antiarrhythmic	Arrhythmia	A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.	PubMed search Quinidine)	DrugBank search Quinidine
Quinine		Classified as QT prolonging drug			An alkaloid used to treat uncomplicated Plasmodium falciparum malaria.	PubMed search Quinine)	DrugBank search Quinine
Quinine sulfate	Qualaquin, Hexaquine	High risk	Antimalarial	Malaria, leg cramps		PubMed search Quinine sulfate)	DrugBank search Quinine sulfate
Ranolazine	Ranexa, Ranozex	Low risk	Antianginal	Angina Pectoris (heart pain)	An anti-anginal drug used for the treatment of chronic angina.	PubMed search Ranolazine)	DrugBank search Ranolazine
Relugolix	Orgovyx, Relumina	Classified as QT prolonging drug	GnRH antagonist	Cancer (prostate)	An oral GnRH receptor antagonist for androgen deprivation therapy in the treatment of advanced prostate cancer.	PubMed search Relugolix)	DrugBank search Relugolix
Remimazolam	Byfavo	Classified as QT prolonging drug	Sedative	Sedation		PubMed search Remimazolam)	DrugBank search Remimazolam
Ribociclib	Kisqali	Moderate risk	Anti-cancer	Cancer (breast)		PubMed search Ribociclib)	DrugBank search Ribociclib
Ricolinostat		Classified as QT prolonging drug			Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer.	PubMed search Ricolinostat)	DrugBank search Ricolinostat
Rilpivirine	Edurant, Complera, Eviplera, Juluca	Low to moderate risk	Antiviral	Viral infection (HIV/AIDS)	A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1).	PubMed search Rilpivirine)	DrugBank search Rilpivirine
Risperidone	Risperdal	Moderate risk	Antipsychotic, atypical	Schizophrenia	A second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression.	PubMed search Risperidone)	DrugBank search Risperidone
Ritodrine	Yutopar	Classified as QT prolonging drug	Muscle relaxant	Premature labor		PubMed search Ritodrine)	DrugBank search Ritodrine
Ritonavir		Classified as QT prolonging drug			An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.	PubMed search Ritonavir)	DrugBank search Ritonavir
Romidepsin	Istodax	Low risk	Histone deacetylase inhibitor	Cancer (lymphoma)	A histone deacetylase (HDAC) inhibitor used to treat cutaneous T-cell lymphoma.	PubMed search Romidepsin)	DrugBank search Romidepsin
Rosoxacin		Classified as QT prolonging drug			For the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients.	PubMed search Rosoxacin)	DrugBank search Rosoxacin
Roxithromycin	Rulide, Xthrocin, Roxl-150, Roxo, Surlid, Rulide, Biaxsig, Roxar, Roximycinv, Roxomycin, Rulid, Tirabicin, Coroxin	Low to moderate risk	Antibiotic	Bacterial infection	An antibiotic used to treat a variety of susceptible bacterial infections.	PubMed search Roxithromycin)	DrugBank search Roxithromycin
Rucaparib	Rubraca	Classified as QT prolonging drug	PARP inhibitor	Cancer		PubMed search Rucaparib)	DrugBank search Rucaparib
Salbutamol		Classified as QT prolonging drug			A beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms.	PubMed search Salbutamol)	DrugBank search Salbutamol
Salmeterol	Serevent, Advair	Low risk	Bronchodilator	Asthma	A long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD.	PubMed search Salmeterol)	DrugBank search Salmeterol
Saquinavir	Invirase	Moderate risk	Antiviral	Viral infection (HIV/AIDS)	An HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency.	PubMed search Saquinavir)	DrugBank search Saquinavir
Sarafloxacin		Classified as QT prolonging drug			Sarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada.	PubMed search Sarafloxacin)	DrugBank search Sarafloxacin
Selpercatinib	Retevmo	High risk	Kinase inhibitor	Lung cancer		PubMed search Selpercatinib)	DrugBank search Selpercatinib
Sertindole	Serdolect, Serlect	High risk	Antipsychotic, atypical	Schizophrenia, anxiety	An atypical antipsychotic indicated in the treatment of schizophrenia.	PubMed search Sertindole)	DrugBank search Sertindole
Sertraline	Zoloft, Lustral	Low to moderate risk	Antidepressant, SSRI	Depression		PubMed search Sertraline)	DrugBank search Sertraline
Sevoflurane	Ultane, Sojourn	Classified as QT prolonging drug	Anesthetic, general	Anesthesia	A inhalation anaesthetic agent used for induction and maintenance of general anesthesia during surgical procedures.	PubMed search Sevoflurane)	DrugBank search Sevoflurane
Sibutramine	Meridia	Classified as QT prolonging drug	Appetite suppressant	Obesity		PubMed search Sibutramine)	DrugBank search Sibutramine
Simendan		Classified as QT prolonging drug			Simendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure).	PubMed search Simendan)	DrugBank search Simendan
Siponimod	Mayzent	Classified as QT prolonging drug		Multiple Sclerosis		PubMed search Siponimod)	DrugBank search Siponimod
Solifenacin	Vesicare	Classified as QT prolonging drug	Muscle relaxant	Bladder spasm	A muscarinic antagonist with antispasmodic properties used to treat urge urinary incontinence, urgency, and urinary frequency associated with an overactive bladder.	PubMed search Solifenacin)	DrugBank search Solifenacin
Sorafenib	Nexavar	Low risk	Anti-cancer	Cancer (liver, renal cell, metastatic thyroid)	A kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma.	PubMed search Sorafenib)	DrugBank search Sorafenib
Sotalol	Betapace, Sotalex, Sotacor, Sotalol-AF	Classified as QT prolonging drug	Antiarrhythmic	Arrhythmia	A methane sulfonanilide beta adrenergic antagonist used to treat life-threatening ventricular arrhythmias and to maintain sinus rhythm in atrial fibrillation or flutter.	PubMed search Sotalol)	DrugBank search Sotalol
Sparfloxacin	Zagam	Moderate risk	Antibiotic	Bacterial infection	A fluoroquinolone antibiotic used to treat bacterial respiratory infections and sinusitis.	PubMed search Sparfloxacin)	DrugBank search Sparfloxacin
Sulfamethoxazole		Classified as QT prolonging drug			An oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract.	PubMed search Sulfamethoxazole)	DrugBank search Sulfamethoxazole
Sulfamethoxazole and Trimethoprim	Septra, Bactrim, Sulfatrim, Biseptol, Co-trimoxazole, Cotrim, Septrin, Trisul	Classified as QT prolonging drug	Antibiotic	Bacterial infection		PubMed search Sulfamethoxazole and Trimethoprim)	DrugBank search Sulfamethoxazole and Trimethoprim
Sulfisoxazole		Classified as QT prolonging drug			A sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections.	PubMed search Sulfisoxazole)	DrugBank search Sulfisoxazole
Sulpiride	Dogmatil, Dolmatil, Eglonyl, Espiride, Modal, Sulpor	Classified as QT prolonging drug	Antipsychotic, atypical	Schizophrenia	A selective D2 dopamine receptor antagonist indicated to treat chronic and acute schizophrenia.	PubMed search Sulpiride)	DrugBank search Sulpiride
Sultopride	Barnetil, Barnotil, Topral	Classified as QT prolonging drug	Antipsychotic, atypical	Schizophrenia	Sultopride is used in Japan, Hong Kong, and Europe to treat schizophrenia. It is of the drug class atypical antipsychotics .	PubMed search Sultopride)	DrugBank search Sultopride
Sunitinib	Sutent	Moderate risk	Anti-cancer	Cancer (GIST, renal cell, pNET)	A receptor tyrosine kinase inhibitor and chemotherapeutic agent used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).	PubMed search Sunitinib)	DrugBank search Sunitinib
Tacrolimus	Prograf, Prograf, Advagraf, Protopic	Classified as QT prolonging drug	Immunosuppressant	Immune suppression		PubMed search Tacrolimus)	DrugBank search Tacrolimus
Talinolol		Classified as QT prolonging drug			Talinolol has been investigated for the basic science of Gastrointestinal Motility Disorder.	PubMed search Talinolol)	DrugBank search Talinolol
Tamoxifen	Nolvadex, Istubal	Low risk	Anti-cancer	Cancer (breast)	A selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women.	PubMed search Tamoxifen)	DrugBank search Tamoxifen
Tandutinib		Classified as QT prolonging drug			Investigated for use/treatment in leukemia (myeloid).	PubMed search Tandutinib)	DrugBank search Tandutinib
Tazemetostat	Tazverik	Classified as QT prolonging drug	Anti-cancer	Epithelioid sarcoma		PubMed search Tazemetostat)	DrugBank search Tazemetostat
Technetium Tc-99m ciprofloxacin		Classified as QT prolonging drug			Investigated for use/treatment in infectious and parasitic disease (unspecified).	PubMed search Technetium Tc-99m ciprofloxacin)	DrugBank search Technetium Tc-99m ciprofloxacin
Tedisamil		Classified as QT prolonging drug			Investigated for use/treatment in arrhythmia, atrial fibrillation, and angina.	PubMed search Tedisamil)	DrugBank search Tedisamil
Telaprevir	Incivo, Incivek	Classified as QT prolonging drug	Antiviral	Viral infection (hepatitis C)		PubMed search Telaprevir)	DrugBank search Telaprevir
Telavancin	Vibativ	Low risk	Antibiotic	Bacterial infection	An antibacterial agent used in the treatment of complicated skin and skin structure infections and types of hospital-acquired bacterial pneumonia.	PubMed search Telavancin)	DrugBank search Telavancin
Telithromycin	Ketek	Low to moderate risk	Antibiotic	Bacterial infection	An ketolide used to treat community acquired pneumonia of mild to moderate severity.	PubMed search Telithromycin)	DrugBank search Telithromycin
Temafloxacin		Classified as QT prolonging drug			For the treatment of lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections.	PubMed search Temafloxacin)	DrugBank search Temafloxacin
Temefos		Classified as QT prolonging drug			Diphos has been used in trials studying the treatment of Plasmodium Falciparum Malaria.	PubMed search Temefos)	DrugBank search Temefos
Terbutaline	Brethine, Bricanyl, Brethaire, Terbulin	Moderate risk	Bronchodilator	Asthma, premature labor	A beta-2 adrenergic agonist used as a bronchodilator and to prevent premature labor.	PubMed search Terbutaline)	DrugBank search Terbutaline
Terfenadine	Seldane	Classified as QT prolonging drug	Antihistamine	Allergic rhinitis	An antihistamine for the treatment of allergy symptoms.	PubMed search Terfenadine)	DrugBank search Terfenadine
Terlipressin	Teripress, Glypressin, Terlipin, Remestyp, Tresil, Teriss	Low to moderate risk	Vasoconstrictor	Septic shock	A drug used to treat bleeding caused by esophageal varices.	PubMed search Terlipressin)	DrugBank search Terlipressin
Terodiline	Micturin, Mictrol	Classified as QT prolonging drug	Muscle relaxant	Bladder spasm	Not Annotated	PubMed search Terodiline)	DrugBank search Terodiline
Tetrabenazine	Nitoman, Xenazine	Low to moderate risk	Vesicular Monoamine Transporter 2 Inhibitor	Chorea (Huntington's disease)	A vesicular monoamine transporter 2 (VMAT) inhibitor used for the management of chorea associated with Huntington's Disease.	PubMed search Tetrabenazine)	DrugBank search Tetrabenazine
Tetrahydropalmatine		Classified as QT prolonging drug			Tetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity).	PubMed search Tetrahydropalmatine)	DrugBank search Tetrahydropalmatine
Thioridazine	Mellaril, Novoridazine, Thioril	Moderate risk	Antipsychotic	Schizophrenia	A phenothiazine antipsychotic used to treat schizophrenia and generalized anxiety disorder.	PubMed search Thioridazine)	DrugBank search Thioridazine
Thiothixene		Classified as QT prolonging drug			An antipsychotic indicated for the management of schizophrenia.	PubMed search Thiothixene)	DrugBank search Thiothixene
Tiapride	Tiapridal, Italprid, Sereprile, Tialaread, Tiaryl, Tiaprim, Tiaprizal, Sereprid, Tiapridex	Classified as QT prolonging drug	Selective D2, D3 dopamine antagonist	Alcoholism, withdrawal		PubMed search Tiapride)	DrugBank search Tiapride
Tipiracil/Trifluridine	Lonsurf	Classified as QT prolonging drug	Anti-cancer	Cancer (Metastatic colorectal)		PubMed search Tipiracil/Trifluridine)	DrugBank search Tipiracil/Trifluridine
Tizanidine	Zanaflex, Sirdalud	Classified as QT prolonging drug	Muscle relaxant	Muscle spasticity	An alpha-2 adrenergic agonist used for the short-term treatment of muscle spasticity.	PubMed search Tizanidine)	DrugBank search Tizanidine
Tolterodine	Detrol, Detrusitol	Classified as QT prolonging drug	Muscle relaxant	Bladder spasm	A muscarinic receptor antagonist used to treat overactive bladder with urinary incontinence, urgency, and frequency.	PubMed search Tolterodine)	DrugBank search Tolterodine
Torasemide	Demadex, Diuver, Examide	Classified as QT prolonging drug	Diuretic	Hypertension, diuresis		PubMed search Torasemide)	DrugBank search Torasemide
Toremifene	Fareston	Moderate risk	Estrogen agonist/antagonist	Cancer (breast, metastatic)	A first generation nonsteroidal selective estrogen receptor modulator used to treat certain breast cancers.	PubMed search Toremifene)	DrugBank search Toremifene
Tramadol	Crispin, Ralivia ER, Ralivia Flashtab, Tramadolum, Tramal, Tramodol, Tridural, Ultram, Ultram ER, Zydol, Ixprim, Zaldiar, Topalgic	Classified as QT prolonging drug	Analgesic	Pain		PubMed search Tramadol)	DrugBank search Tramadol
Trazodone	Desyrel, Oleptro, Beneficat, Deprax, Desirel, Molipaxin, Thombran, Trazorel, Trialodine, Trittico, Mesyrel	Low to moderate risk	Antidepressant, SARI	Depression, insomnia	A serotonin uptake inhibitor used to treat major depressive disorder.	PubMed search Trazodone)	DrugBank search Trazodone
Treprostinil		Classified as QT prolonging drug			A prostacyclin vasodilator for the treatment of pulmonary arterial hypertension to relieve exercise associated symptoms and to prevent clinical deterioration after stopping epoprostenol.	PubMed search Treprostinil)	DrugBank search Treprostinil
Triclabendazole		Classified as QT prolonging drug			An anthelmintic drug used to treat fascioliasis.	PubMed search Triclabendazole)	DrugBank search Triclabendazole
Trimethadione		Classified as QT prolonging drug			An anticonvulsant agent indicated for the control of treatment-refractory petit mal seizures.	PubMed search Trimethadione)	DrugBank search Trimethadione
Trimipramine	Surmontil, Rhotrimine, Stangyl	Classified as QT prolonging drug	Antidepressant, Tricyclic	Depression	A tricyclic antidepressant used to treat depression.	PubMed search Trimipramine)	DrugBank search Trimipramine
Triptorelin		Classified as QT prolonging drug			A GnRH agonist indicated for the palliative treatment of advanced prostate cancer.	PubMed search Triptorelin)	DrugBank search Triptorelin
Tropisetron	Navoban, Setrovel	Low to moderate risk	Antiemetic	Nausea, vomiting		PubMed search Tropisetron)	DrugBank search Tropisetron
Trovafloxacin		Classified as QT prolonging drug			An antibiotic used to treat gonorrhea and chlamydia.	PubMed search Trovafloxacin)	DrugBank search Trovafloxacin
Tucidinostat		Classified as QT prolonging drug			Investigated for use/treatment in cancer/tumors (unspecified).	PubMed search Tucidinostat)	DrugBank search Tucidinostat
Valbenazine	Ingrezza	Classified as QT prolonging drug	Vesicular monamine transporter 2 inhibitor	Tardive Dyskinesia		PubMed search Valbenazine)	DrugBank search Valbenazine
Valproic acid		Classified as QT prolonging drug			An anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.	PubMed search Valproic acid)	DrugBank search Valproic acid
Vandetanib	Caprelsa	High risk	Anti-cancer	Cancer (thyroid)	An antineoplastic kinase inhibitor used to treat symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease.	PubMed search Vandetanib)	DrugBank search Vandetanib
Vardenafil	Levitra	Classified as QT prolonging drug	Phosphodiesterase 5 inhibitor	Erectile dysfunction	A phosphodiesterase 5 inhibitor used to treat erectile dysfunction.	PubMed search Vardenafil)	DrugBank search Vardenafil
Vemurafenib	Zelboraf	Moderate risk	Anti-cancer	Cancer (melanoma)	A kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation.	PubMed search Vemurafenib)	DrugBank search Vemurafenib
Venlafaxine	Effexor, Efexor	Classified as QT prolonging drug	Antidepressant, SNRI	Depression	A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression, generalized or social anxiety disorder, and panic disorder.	PubMed search Venlafaxine)	DrugBank search Venlafaxine
Vernakalant	Brinavess	High risk	Antiarrhythmic drug	Atrial fibrillation	An antiarrhythmic medication used to treat patients with atrial fibrillation.	PubMed search Vernakalant)	DrugBank search Vernakalant
Vilanterol		Classified as QT prolonging drug			A long-acting beta2-adrenergic agonist used in combination with other bronchodilators for the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.	PubMed search Vilanterol)	DrugBank search Vilanterol
Vilanterol/fluticasone furoate	Breo Ellipta	Low risk	Bronchodilator	Asthma		PubMed search Vilanterol/fluticasone furoate)	DrugBank search Vilanterol/fluticasone furoate
Voclosporin	Lupkynis	Low to moderate risk	Immunosupressant	Lupus nephritis		PubMed search Voclosporin)	DrugBank search Voclosporin
Voriconazole	VFend	Moderate risk	Antifungal	Fungal infection	A triazole compound used to treat fungal infections.	PubMed search Voriconazole)	DrugBank search Voriconazole
Vorinostat	Zolinza	Low risk	Histone deacetylase inhibitor	Cancer (lymphoma)	A histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies.	PubMed search Vorinostat)	DrugBank search Vorinostat
Xylometazoline (Xylomethazoline)	Sinosil, Aqua Maris	Classified as QT prolonging drug	Sympathomimetic	Nasal Congestion		PubMed search Xylometazoline (Xylomethazoline))	DrugBank search Xylometazoline (Xylomethazoline)
Ziprasidone	Geodon, Zeldox	High risk	Antipsychotic, atypical	Schizophrenia	An atypical antipsychotic used to manage schizophrenia, bipolar mania, and agitation in patients with schizophrenia.	PubMed search Ziprasidone)	DrugBank search Ziprasidone
Zotepine	Losizopilon, Lodopin, Setous, Zoleptil	Classified as QT prolonging drug	Antipsychotic, atypical	Schizophrenia		PubMed search Zotepine)	DrugBank search Zotepine
Zuclopenthixol		Classified as QT prolonging drug			An antipsychotic indicated for the management of schizophrenia. The acuphase formulation is indicated for initial treatment of acute psychosis or exacerbation of psychosis, while the depot formulation is best for maintenance.	PubMed search Zuclopenthixol)	DrugBank search Zuclopenthixol
Zuclopenthixol (Zuclopentixol)	Cisordinol, Clopixol, Acuphase	Classified as QT prolonging drug	Antipsychotic	Psychosis		PubMed search Zuclopenthixol (Zuclopentixol))	DrugBank search Zuclopenthixol (Zuclopentixol)

🟠 QT Drugs: Drugs causing QT prolongation, torsade de pointes (TdP) and long QT syndrome (LQTS)

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