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Cardiovascular Risk in Inflammatory and Autoimmune Disease

…years, compared with 15.0 per 1000 patient years in age matched controls without autoimmune disease. The greatest risks were reported with systemic sclerosis, Addison…

Leg ulcers — wound debridement and compression therapy

…and in patients with diabetes or renal failure the index may be falsely normal because of medial sclerosis — in that case add toe pressure measurement…

Pulmonary Hypertension: Classification and Treatment Principles

…or associated with conditions such as systemic sclerosis, HIV infection, cirrhosis, and sickle cell disease. The classification also recognizes vasoreactivity subgroups among patients with idiopathic…

Hypertensive crisis: quick reference for acute blood pressure lowering

…Episodes of headache, palpitations, sweating and pallor that may suggest phaeochromocytoma. Systemic sclerosis, kidney disease, autoimmune disease or previous thrombotic microangiopathy. Antidepressants can affect the…

Anaphylaxis: quick reference for emergency management

…grading There are several grading systems, and no grading replaces immediate clinical assessment. The updated international grading comprises five levels, with mild skin and mucosal…

Cardiac arrest during sepsis

…condition characterized by systemic inflammatory response syndrome (SIRS), disseminated intravascular coagulation (DIC), and hypoperfusion manifesting as hypotension. The high mortality associated with sepsis underscores the…

🟠 Fenoldopam

…action • Systemic Dopamine 1 (D1) receptor agonist. • Lowers blood pressure while maintaining or increasing kidney perfusion. Effects Dopamine 1 receptor agonists lower systemic blood pressure…

🟠 Calculating Shunt Fraction (Qp/Qs) Using Echocardiography

…The shunt fraction (Qp/Qs) is a critical hemodynamic parameter used to quantify the ratio of pulmonary blood flow (Qp) to systemic blood flow (Qs)…

🟠 Hydralazine

…stimulation (can be counteracted with simultaneous administration of beta blockers). Effects Induces arteriolar vasodilation without effects on venous circulation. The reduction in systemic vascular resistance …

Amiodarone: Loading, Maintenance Dosing and Monitoring Schedule

…and incompletely absorbed after oral administration, with systemic bioavailability ranging from 25% to 65% and minimal hepatic first pass extraction. Following a single oral dose…

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