Articles & courses

Articles
Nail procedures — paronychia, ingrown toenail and subungual haematoma

…often with chemical matrix ablation A nail spicule that has split off Removal of the spicule A painful subungual haematoma with an intact nail plate…

Ezetimibe: Place in Therapy and Expected LDL-C Reduction

…reduction required is greater than can reasonably be obtained with a statin alone but does not necessarily require the larger effect of a PCSK9 inhibitor…

Inclisiran and Emerging Lipid-Lowering Agents

…be considered within a stepwise, target based lipid lowering strategy: Dietary and lifestyle interventions form the foundation of treatment. Statins are the preferred first line…

Statin Intolerance and Statin-Associated Muscle Symptoms

…methylglutaryl coenzyme A reductase, the rate limiting enzyme in cholesterol synthesis. Reduced hepatic cholesterol production increases hepatic LDL receptor expression, thereby enhancing removal of LDL…

PCSK9 Inhibitors: Indications, Efficacy and Access

…PCSK9) is a hepatic protein that regulates the availability of the low density lipoprotein receptor (LDL receptor) on hepatocytes. By directing the receptor toward intracellular…

Extracorporeal cardiopulmonary resuscitation (ECPR)

…a type of ECLS, operates by drawing venous blood from the patient to an oxygenator (gas exchanger), where it undergoes oxygenation and carbon dioxide removal…

Otoscopy and ear syringing

…Removal of cerumen: Hearing loss, a blocked sensation, itching, earache or dizziness attributable to a wax plug. The tympanic membrane cannot be inspected and the…

Eye examination and corneal foreign body

…Removal Proceed from the least to the most invasive technique. 1. Irrigate with sterile saline — loose particles often come away. 2. A moistened cotton bud…

Periprocedural Myocardial Infarction After PCI and CABG

…MI after PCI In a patient with normal baseline cTn, type 4a MI is defined by: cTn greater than 5 times the 99th percentile upper…

Torsades de Pointes: Definition, Characteristics, and Management

…Addressing the underlying precipitating factors is a critical component of acute management [4]: Electrolyte Management : Correction of electrolyte derangements is essential [4]. Volume Removal and…

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