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Articles
Nail procedures — paronychia, ingrown toenail and subungual haematoma

…or a drain Ingrown nail, severe or recurrent Partial nail avulsion, often with chemical matrix ablation A nail spicule that has split off Removal of…

Ezetimibe: Place in Therapy and Expected LDL-C Reduction

…quantity of cholesterol delivered to the liver. The resulting hepatic response includes increased expression of low density lipoprotein receptors (LDLRs), which enhances removal of circulating…

Extracorporeal cardiopulmonary resuscitation (ECPR)

…rhythm is non shockable, as seen in certain causes of cardiac arrest (e.g. pulmonary embolism) or in case of long no flow or low…

Inclisiran and Emerging Lipid-Lowering Agents

…PCSK9. The prolonged intracellular effect of inclisiran permits subcutaneous administration only twice yearly, an important practical distinction from therapies requiring monthly or biweekly injections. Inclisiran…

Statin Intolerance and Statin-Associated Muscle Symptoms

…doses are therefore appropriate. Drug interactions are particularly important. Inhibition of cytochrome P 450 3A4 or 2C9 can increase statin concentrations. Relevant interacting agents include…

PCSK9 Inhibitors: Indications, Efficacy and Access

…syndrome, the recommended LDL C objective is: LDL C <1.4 mmol/L (<55 mg/dL) , and A reduction of at least 50% from baseline …

Otoscopy and ear syringing

…before every ear syringing. Removal of cerumen: Hearing loss, a blocked sensation, itching, earache or dizziness attributable to a wax plug. The tympanic membrane cannot…

Eye examination and corneal foreign body

…s zygoma or the bridge of the nose. 4. Approach tangentially from the periphery , never through the visual axis, with a spud or a needle…

Periprocedural Myocardial Infarction After PCI and CABG

…troponin is elevated but stable or falling, the postprocedural level must demonstrate both the required absolute threshold and a rise of more than 20% from…

Torsades de Pointes: Definition, Characteristics, and Management

…block (SGB) or cardiac surgical sympathetic denervation can be performed to mechanically reduce sympathetic output [4]. Evaluation of Treatment and Alternatives for Drug Failure The…

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