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Statin Intolerance and Statin-Associated Muscle Symptoms

…thereby enhancing removal of LDL particles from the circulation. Statins also reduce production of apoB 100 containing lipoproteins and exert effects beyond LDL C reduction…

Inclisiran and Emerging Lipid-Lowering Agents

…the availability of hepatic low density lipoprotein cholesterol (LDL C) receptors at the cell surface, and thereby enhances removal of LDL C from the circulation…

Ezetimibe: Place in Therapy and Expected LDL-C Reduction

…C <1.4 mmol/L (<55 mg/dL), and at least a 50% reduction from baseline. For a patient who experiences a recurrent atherothrombotic event…

PCSK9 Inhibitors: Indications, Efficacy and Access

…associated with protection from cardiovascular disease. Pharmacological PCSK9 inhibition increases the effective availability of hepatic LDL receptors and thereby enhances LDL C removal from plasma…

Nail procedures — paronychia, ingrown toenail and subungual haematoma

…gauze. The digital block Anaesthetise from the dorsal aspect, one injection medial and one lateral to the base of the phalanx, 2–3 mL on…

Extracorporeal cardiopulmonary resuscitation (ECPR)

…type of ECLS, operates by drawing venous blood from the patient to an oxygenator (gas exchanger), where it undergoes oxygenation and carbon dioxide removal, and…

Otoscopy and ear syringing

…dizziness, tinnitus, fever in a child without an obvious focus, and before every ear syringing. Removal of cerumen: Hearing loss, a blocked sensation, itching, earache…

Eye examination and corneal foreign body

…and the chin in the rest. Support your working hand against the patient's zygoma or the bridge of the nose. 4. Approach tangentially from…

Periprocedural Myocardial Infarction After PCI and CABG

…stable or falling, the postprocedural level must demonstrate both the required absolute threshold and a rise of more than 20% from baseline. Type 4a MI…

Torsades de Pointes: Definition, Characteristics, and Management

…assess rhythm stability [10]. References International guideline (EU) — Drug Induced Torsades De Pointes CLINICAL DESCRIPTION AND MANIFESTATIONS OF DRUG INDUCED TORSADES DE POINTES. International gui

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