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Articles
Torsades de Pointes: Definition, Characteristics, and Management

…contexts [4]. Reduction of Sympathetic Drive Modulating autonomic tone is a pivotal therapeutic target [4]: Beta Blockers : Administered to reduce adrenergic stimulation [4]. Sedation and…

Nail procedures — paronychia, ingrown toenail and subungual haematoma

…gauze. The digital block Anaesthetise from the dorsal aspect, one injection medial and one lateral to the base of the phalanx, 2–3 mL on…

Ezetimibe: Place in Therapy and Expected LDL-C Reduction

…quantity of cholesterol delivered to the liver. The resulting hepatic response includes increased expression of low density lipoprotein receptors (LDLRs), which enhances removal of circulating…

Inclisiran and Emerging Lipid-Lowering Agents

…the availability of hepatic low density lipoprotein cholesterol (LDL C) receptors at the cell surface, and thereby enhances removal of LDL C from the circulation…

Statin Intolerance and Statin-Associated Muscle Symptoms

…should be distinguished from severe muscle injury. Myopathy is characterized by muscle symptoms accompanied by CK greater than 10 times the upper limit of no

PCSK9 Inhibitors: Indications, Efficacy and Access

…associated with protection from cardiovascular disease. Pharmacological PCSK9 inhibition increases the effective availability of hepatic LDL receptors and thereby enhances LDL C removal from plasma…

Extracorporeal cardiopulmonary resuscitation (ECPR)

…a type of ECLS, operates by drawing venous blood from the patient to an oxygenator (gas exchanger), where it undergoes oxygenation and carbon dioxide removal…

Otoscopy and ear syringing

…tinnitus, fever in a child without an obvious focus, and before every ear syringing. Removal of cerumen: Hearing loss, a blocked sensation, itching, earache or…

Eye examination and corneal foreign body

…the rest. Support your working hand against the patient's zygoma or the bridge of the nose. 4. Approach tangentially from the periphery , never through…

Periprocedural Myocardial Infarction After PCI and CABG

…stable or falling, the postprocedural level must demonstrate both the required absolute threshold and a rise of more than 20% from baseline. Type 4a MI…

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