Articles & courses

Articles
Eye examination and corneal foreign body

…syringe for irrigation. An eye shield (never a pressure dressing when perforation is suspected). A tonometer: an applanation tonometer on the slit lamp, or a…

Otoscopy and ear syringing

…tinnitus, fever in a child without an obvious focus, and before every ear syringing. Removal of cerumen: Hearing loss, a blocked sensation, itching, earache or…

Nail procedures — paronychia, ingrown toenail and subungual haematoma

…from the dorsal aspect, one injection medial and one lateral to the base of the phalanx, 2–3 mL on each side, with the needle…

Ezetimibe: Place in Therapy and Expected LDL-C Reduction

…quantity of cholesterol delivered to the liver. The resulting hepatic response includes increased expression of low density lipoprotein receptors (LDLRs), which enhances removal of circulating…

Inclisiran and Emerging Lipid-Lowering Agents

…with more frequent injectable therapy, although the clinical importance of improved adherence remains dependent on sustained follow up and administration. Clinical indications and place in…

Statin Intolerance and Statin-Associated Muscle Symptoms

…thereby enhancing removal of LDL particles from the circulation. Statins also reduce production of apoB 100 containing lipoproteins and exert effects beyond LDL C reduction…

PCSK9 Inhibitors: Indications, Efficacy and Access

…Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a hepatic protein that regulates the availability of the low density lipoprotein receptor (LDL receptor) on hepatocytes…

Extracorporeal cardiopulmonary resuscitation (ECPR)

…a stable return of spontaneous circulation (ROSC). Stable ROSC is when spontaneous circulation is maintained for 20 consecutive minutes, without the need for chest compressions…

Periprocedural Myocardial Infarction After PCI and CABG

…of collateral flow Distal embolization Stent thrombosis Graft occlusion after CABG No reflow despite removal of an apparent epicardial stenosis The clinical consequences depend on…

Torsades de Pointes: Definition, Characteristics, and Management

…estimated incidence of DI LQTS and DI TdP is drug dependent, ranging between 1% and 8% for Class III antiarrhythmic agents depending on the specific…

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