Articles & courses

Articles
Inclisiran and Emerging Lipid-Lowering Agents

…with more frequent injectable therapy, although the clinical importance of improved adherence remains dependent on sustained follow up and administration. Clinical indications and place in…

Ezetimibe: Place in Therapy and Expected LDL-C Reduction

…remains the foundation of lipid lowering treatment for patients with chronic coronary syndrome, acute coronary syndrome (ACS), atherosclerotic peripheral arterial disease, and other very high…

Nail procedures — paronychia, ingrown toenail and subungual haematoma

…from the dorsal aspect, one injection medial and one lateral to the base of the phalanx, 2–3 mL on each side, with the needle…

Statin Intolerance and Statin-Associated Muscle Symptoms

…thereby enhancing removal of LDL particles from the circulation. Statins also reduce production of apoB 100 containing lipoproteins and exert effects beyond LDL C reduction…

PCSK9 Inhibitors: Indications, Efficacy and Access

…Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a hepatic protein that regulates the availability of the low density lipoprotein receptor (LDL receptor) on hepatocytes…

Extracorporeal cardiopulmonary resuscitation (ECPR)

…a stable return of spontaneous circulation (ROSC). Stable ROSC is when spontaneous circulation is maintained for 20 consecutive minutes, without the need for chest compressions…

Otoscopy and ear syringing

…tinnitus, fever in a child without an obvious focus, and before every ear syringing. Removal of cerumen: Hearing loss, a blocked sensation, itching, earache or…

Eye examination and corneal foreign body

…Grasp the eyelashes, press gently downwards on the upper border of the tarsal plate with a cotton bud, and at the same time fold the…

Periprocedural Myocardial Infarction After PCI and CABG

…of collateral flow Distal embolization Stent thrombosis Graft occlusion after CABG No reflow despite removal of an apparent epicardial stenosis The clinical consequences depend on…

Torsades de Pointes: Definition, Characteristics, and Management

…estimated incidence of DI LQTS and DI TdP is drug dependent, ranging between 1% and 8% for Class III antiarrhythmic agents depending on the specific…

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