…Note the pupil size, shape and reaction to light. A teardrop shaped or peaked pupil suggests perforation. Look for hyphaema — blood with a fluid level…

…septal perforation has been described after as little as seven hours. Never irrigate and never instil fluid onto a battery — the moisture drives the reaction…

…electrocautery is used Relative A cochlear implant Relative The contralateral side of the septum already cauterised — bilateral cautery carries a risk of perforation Anterior packing…

…wax retains moisture. Contraindications Absolute contraindications to irrigation: A known or suspected perforation of the tympanic membrane — including a history of grommets, ear discharge or…

…0.38 Vascular complications 0.43 Contrast agent reaction 0.37 Haemodynamic complications 0.26 Cardiac chamber perforation 0.03 Other complications 0.28 Total…

…vascular lesions. The interleukin 1β pathway, with downstream effects involving interleukin 6 and C reactive protein, has been a major therapeutic target. This concept…

…C, non high density lipoprotein cholesterol, apolipoprotein B and high sensitivity C reactive protein (hsCRP). Bempedoic acid also activates adenosine monophosphate activated protein kinase, which…

…angiographic reduction of coronary obstruction. Intensive lipid lowering improves endothelial function, lowers circulating high sensitivity C reactive protein, reduces thrombogenicity, and favourably modifies inflammatory and…

…They are contraindicated in patients with bronchospastic lung disease, or a history of significant reactive airway disease. Contraindications also include second degree or third degree…

…within the subendothelial space, LDL C particles undergo oxidative modification by reactive oxygen species (ROS) and enzymes such as myeloperoxidase and lipoxygenase. Oxidized LDL (oxLDL…