…is the first line treatment in high risk embolism, unless there is an absolute contraindication. The agent and dose are according to the local protocol…

…not a treatment review. For a fuller account of two of the commonest acute drug problems, see Warfarin therapy and Opioid therapy in severe pain…

…before a blood count is available. The nadir often occurs 7 to 14 days after a course of chemotherapy, but the timing varies considerably between…

…the shape of the tip and the technique that matter, not the calibre; choose instead the smallest size that will do the job, to reduce…

…ventilation–perfusion matching, increased physiological dead space and the Haldane effect. It is therefore misleading to explain the whole phenomenon as abolition of the patie

…is comparable to common cancers ( Stewart et al ). In addition, heart failure is a disabling condition with a very negative impact on quality of life…

…is comparable to common cancers ( Stewart et al ). In addition, heart failure is a disabling condition with a very negative impact on quality of life…

…for 50% of all years of life lost due to cardiovascular disease ( Myerburg et al ). Sudden unexpected cardiac arrest is the mechanism of death for…

…thrombogenic and pro thrombolytic factors determines whether atherothrombosis occurs, and these factors vary from minute to minute. Only a minority of all plaque disruptions resul

…itself leads to impaired right ventricular function, especially if the load becomes prolonged. However, most often the cause of the load is the primary problem…

…plumbing problem characterized by the gradual accumulation of inert cholesterol debris, modern vascular biology has redefined atherosclerosis as a dynamic, immune mediated fibroproliferative response to…

…unknown or if disease progression is suspected. Reversible causes may account for up to 50% of SCA cases, though determining the exact underlying cause and…

…z score with a lower limit of normal at z = −1.64 (the fifth percentile) has been recommended in preference to fixed percentage thresholds…

…In life threatening haemorrhage without a valid blood group, give group O RhD negative blood (always RhD negative to women of childbearing age) while awaiting…

…the capacity to identify, prospectively, those individuals genuinely at risk of arrest. This predictive problem has proven persistently resistant to resolution. Known predictors of cardiac…

…factors are particularly important because correction of the underlying problem is necessary for durable treatment. Intracoronary imaging is encouraged to define the mechanism rather than…