…with uric acid nephropathy. Thrombotic Thrombocytopenic Purpura (TTP): In very rare cases, TTP has been reported with ticagrelor treatment. TTP is characterized by thrombocytopenia and…

…outpatient presentations include: Reproducible stress induced angina or ischaemia associated with obstructive epicardial coronary disease. Angina or ischaemia caused by epicardial vasomotor dysfunction or microvascular…

…before surgery, or while swelling is progressing. Take care in impaired sensation (neuropathy, spinal cord injury) — the patient does not feel the pressure sore. Preparation…

…necrotic, pale Variable, often deep Pain Moderate, relieved by elevation Severe, worse on elevation, better when dependent Often painless (neuropathy) Surrounding skin Hyperpigmentation, oedema, lipodermatosclerosis…

…absolute contraindications, but be cautious and consider referral in: Diabetes with neuropathy or peripheral arterial disease — a risk of osteomyelitis and poor healing. Check the…

…time has passed since the injury (see below). Be particularly cautious with impaired healing: peripheral vascular disease, diabetes with neuropathy, immunosuppression, and high dose corticosteroids…

…CKD), which itself promotes cardiovascular disease and amplifies cardiovascular and all cause mortality. The excess risk is mediated by the combined effects of hyperglycaemia, hypertension…

…autonomic neuropathy can at the same time mask the expected tachycardia. Aids to assessment The shock index is calculated as the heart rate divided by…