…and weight) plus vitamin K 10 mg IV Dabigatran Idarucizumab (Praxbind) Apixaban, rivaroxaban, edoxaban Prothrombin complex concentrate, consider within 15 hours of the last dose…

…in renal failure Ketobemidone IV 2.5–5 mg Oral bioavailability about 35 per cent Paracetamol PO or IV 1 g × 4 The basic analgesic…

…effect Within hours. Duration of effect 8 to 24 hours Delivery IV Dose Initial dose: 1.25 mg iv. Increase as necessary. Maximum dose: 5…

…action 50 to 10 minutes Duration of action 30 to 60 minutes Delivery IV Dose Initial infusion dose: 0.1 μg/kg/minute iv…

…5 to 8 hours Delivery IV Dose 1.25 to 5 mg IV followed by 2.5–15 mg IV every 3 to 6 hours…

…2 minutes Duration of action 10 to 30 minutes Delivery IV Dose Bolus injection : 5 to 15 mg every 5 to 15 minutes as necessary…

…to apolipoprotein(a). The length of apolipoprotein(a) varies because of genetically determined differences in the number of kringle IV type 2 repeats. Lp(a)…

…thrombus After cardioversion, irrespective of duration An anticoagulant for at least 4 weeks, thereafter according to CHA₂DS₂ VA The limit is 24 hours, not 48…

…problems, see Warfarin therapy and Opioid therapy in severe pain. Cardiac arrest Drug Adult Child : : : Adrenaline 1 mg IV/IO every 3–5 min. In…

…severe piperacillin–tazobactam 4 g × 4 IV Exacerbation of COPD with an indication for antibiotics amoxicillin 750 mg × 3 PO 5–7 days or doxycycline…

…Dofetilide, Ibutilide, Sotalol Class IV Non dihydropyridine L type Ca 2+ channel blockers Diltiazem, Verapamil Singh–Vaughan Williams classification of antiarrhythmic drugs. Bold text indicates…

…iv. Common therapeutic dose: 4 6 mg/h. Clevidipine is administered in lipid emulsion (containing soy, egg), of which the maximum dose per 24 hours…

…Dose Injection IV: • 150 μg in 1 ml vial. Dilute with 10 ml of normal saline and give by slow injection over 5 10…

…beta adrenergic receptor blocker. • Esmolol lowers blood pressure immediately (within 1 minute) • Esmolol may also be used to control supraventricular tachycardia (rate control). • Esmolol may…

…every 4–6 hours • IM: 10–20 mg every 4–6 hours. Infusion • Afterload reduction : Start infusion at 1 mg/hour. Increase by 0.5…

…iv. Common therapeutic dose: 4 6 mg/h. Clevidipine is administered in lipid emulsion (containing soy, egg), of which the maximum dose per 24 hours…

…Time to onset of action 5 to 10 minutes Duration of action 2 to 4 hours Delivery IV Dose Can be given as repeated intravenous…

…to onset of action 5 to 15 minutes Duration of action 1.5 to 5 hours Delivery IV Dose 5–15 mg/hour IV infusion…

…2 to 5 minutes Duration of action 5 to 10 minutes Delivery IV Dose Initial infusion dose: 5 μg/min. Increase by 5 10…

…minutes Delivery IV Dose Infusion: Starting dose: 0.25 to 0.5 μg/kg/minute. Increased as necessary (increments of 0.5 μg…

…monitoring. The onset of action depends on the route of administration. Intravenous (IV) amiodarone generally acts within 1 to 2 hours. Oral onset is delayed…

…Dofetilide, Ibutilide, Sotalol Class IV Non dihydropyridine L type Ca 2+ channel blockers Diltiazem, Verapamil Singh–Vaughan Williams classification of antiarrhythmic drugs. Bold text indicates…

…Currently, opioid overdose stands as a predominant etiological factor for cardiac arrest within this demographic on a global scale. Numerous substances possess the potential to…

…iv. Common therapeutic dose: 4 6 mg/h. Clevidipine is administered in lipid emulsion (containing soy, egg), of which the maximum dose per 24 hours…

…rheumatoid arthritis, ankylosing spondylitis MACOCHA is validated for the intensive care patient and totals 12 points: Mallampati III–IV (5 points), obstructive sleep apnoea syndrome…

…tongue depressor, a vomit bowl. Local anaesthesia and vasoconstriction: lidocaine 4 % with oxymetazoline 0.5 % (or xylometazoline) on cotton pledgets. Cautery: silver nitrate sticks; electrocautery…

…Bolus : 1 mg IV every 3 to 5 min (max 0.2 mg/kg) IM: (1:1000): 0.1 to 0.5 mg (max 1…

…is 56,5 ml of the 4 mg/ml solution. Cumulative doses of more than 5 mg/kg should not be given within 24 hours…

…class II–IV HFrEF. Advanced or refractory heart failure should be considered when there is recurrent clinical deterioration despite careful follow up and appropriate therapy…

…Hypersensitivity to adenosine. Administration Normal route : Peripheral intravenous (IV). Alternative route : Central venous administration of adenosine is suitable in the intensive care unit or coronary…

…Hyponatremia (<48 hours duration): Rapid correction is preferred. An increase of 1 2 mEq/L per hour for a total of 4 6 mEq/L…

…Bolus : 1 mg IV every 3 to 5 min (max 0.2 mg/kg) IM: (1:1000): 0.1 to 0.5 mg (max 1…

…mg IV. T½ 3 h. 50% renal elimination. • Typically the first choice of drug. • Effective in sinus bradycardia or AV node block. • Dose <0.5…

…is recommended over fibrinolysis within indicated timeframes. I A If timely primary PCI cannot be performed, fibrinolytic therapy is recommended within 12 h of symptom…

…while minimizing battery consumption. Amplitudes are normally below 1.5 V and pulse duration (width) is usually set to 0.5 ms. The relationship between…