…it further. Starting doses in acute pain in an opioid naive adult Agent Route Starting dose Comment : : : : Morphine IV 2.5–5 mg, repeated after…

…effect, and significant individual variations in its effect. Drug Enalaprilat Brand names Vasotec IV ® Indications Hypertension and hypertensive emergency. Acute left ventricular failure. Mechanism…

…action 50 to 10 minutes Duration of action 30 to 60 minutes Delivery IV Dose Initial infusion dose: 0.1 μg/kg/minute iv…

…5 to 8 hours Delivery IV Dose 1.25 to 5 mg IV followed by 2.5–15 mg IV every 3 to 6 hours…

…action 1 to 2 minutes Duration of action 10 to 30 minutes Delivery IV Dose Bolus injection : 5 to 15 mg every 5 to 15…

…to apolipoprotein(a). The length of apolipoprotein(a) varies because of genetically determined differences in the number of kringle IV type 2 repeats. Lp(a)…

…patient. Rate control in the stable patient Drug Situation Comment : : : Beta blocker (metoprolol) First choice in most cases The IV dose is titrated slowly. Caution…

…and Opioid therapy in severe pain. Cardiac arrest Drug Adult Child : : : Adrenaline 1 mg IV/IO every 3–5 min. In asystole and PEA as…

…5–7 days Epiglottitis and other severe upper airway infection cefotaxime 1–2 g × 3 IV Depends on the diagnosis Always assess the severity clinically…

…Dofetilide, Ibutilide, Sotalol Class IV Non dihydropyridine L type Ca 2+ channel blockers Diltiazem, Verapamil Singh–Vaughan Williams classification of antiarrhythmic drugs. Bold text indicates…

…minutes Delivery IV (infusion). Dose Initial dose: 1 2 mg/h iv. Increase as necessary. Rapid titration is possible. Maximum dose: 21 mg/h iv…

…Pain relief. Delivery IV, IM, PO, transdermal Dose Injection IV: • 150 μg in 1 ml vial. Dilute with 10 ml of normal saline and…

…to onset of action 1 minute Duration of action 20 30 minutes Delivery IV Dose Loading dose: 500 μg/kg bolus over 1 minute…

…<4 hours. Delivery IV or IM. Dose Injections • IV: 10–40 mg every 4–6 hours • IM: 10–20 mg every 4–6 hours. Infusion…

…effect, and significant individual variations in its effect. Drug Enalaprilat Brand names Vasotec IV ® Indications Hypertension and hypertensive emergency. Acute left ventricular failure. Mechanism…

…mg every 10 minutes to a total dose of 300 mg. Infusion regime : • 0.5–2 mg/minute IV infusion. Higher doses are sometimes required…

…to onset of action 5 to 15 minutes Duration of action 1.5 to 5 hours Delivery IV Dose 5–15 mg/hour IV infusion…

…to onset of action 2 to 5 minutes Duration of action 5 to 10 minutes Delivery IV Dose Initial infusion dose: 5 μg/min…

…30 seconds to 1 minute Duration of action 1 to 10 minutes Delivery IV Dose Infusion: Starting dose: 0.25 to 0.5 μg…

…monitoring. The onset of action depends on the route of administration. Intravenous (IV) amiodarone generally acts within 1 to 2 hours. Oral onset is delayed…

…Dofetilide, Ibutilide, Sotalol Class IV Non dihydropyridine L type Ca 2+ channel blockers Diltiazem, Verapamil Singh–Vaughan Williams classification of antiarrhythmic drugs. Bold text indicates…

…Botulism Ininum antitoxin Beta blocker Glucagon IV Calcium flow inhibitor (calcium blocker) Calcium iv High dose insulin with glucose IV Carbamates Atropine Pralidoxime chloride Cyanide…

…effect, and significant individual variations in its effect. Drug Enalaprilat Brand names Vasotec IV ® Indications Hypertension and hypertensive emergency. Acute left ventricular failure. Mechanism…

…Reversal in major bleeding Drug Reversal : : Warfarin Prothrombin complex concentrate (dose by INR and weight) plus vitamin K 10 mg IV Dabigatran Idarucizumab (Praxbind) Apixaban…

…hyoid, 2 fingerbreadths from hyoid to the upper border of the thyroid cartilage M allampati Class III–IV indicates increased risk O bstruction/Obesity Stridor…

…compression, cautery, anterior packing — and each step presupposes that the previous one has been done properly. Indications Ongoing epistaxis that has not stopped spontaneously. Recurrent…

…Infusion : 0.01 to 0.10 μg/kg/min Bolus : 1 mg IV every 3 to 5 min (max 0.2 mg/kg) IM…

…10 minutes. A maximum of two infusions can be given. Each infusion should be completed, even if the patient reverts to sinus rhythm. Th e…

…Association (NYHA) classification. The source material specifically frames many pharmacological recommendations for patients with symptomatic NYHA class II–IV HFrEF. Advanced or refractory heart failure…

…Hypersensitivity to adenosine. Administration Normal route : Peripheral intravenous (IV). Alternative route : Central venous administration of adenosine is suitable in the intensive care unit or coronary…

…Confusion Abdominal pain Hypotension Arrhythmias and ECG changes Cardiac arrest Treatment Furosemide 1 mg/kg IV. Hydrocortisone 300 mg IV. Pamidronate 30 90 mg IV…

…Infusion : 0.01 to 0.10 μg/kg/min Bolus : 1 mg IV every 3 to 5 min (max 0.2 mg/kg) IM…

…aminophylline Adenosine receptor antagonist, phosphodiesterase inhibitor. Exact mechanism is unknown. 100−200 mg slow iv injection. Rarely used. Glucagon Counteracts beta blockers. An antidote to…

…Management Recommendation Level of evidence Hypoxia Oxygen is indicated if SaO2 < 90% or PaO2 < 60 mmHg. I C Pain Titrated i.v. opioids…