…specific Fab fragments Ethylene glycol Fomepizo 121:Ethylene Glycol 122:leethanol Heavy metals Chelating substances Ionizing radiation Potassium iodide Iron Deferoxamine Isoniazid Pyridoxine (Vitamin B6…

…it further. Starting doses in acute pain in an opioid naive adult Agent Route Starting dose Comment : : : : Morphine IV 2.5–5 mg, repeated after…

…effect, and significant individual variations in its effect. Drug Enalaprilat Brand names Vasotec IV ® Indications Hypertension and hypertensive emergency. Acute left ventricular failure. Mechanism…

…action 50 to 10 minutes Duration of action 30 to 60 minutes Delivery IV Dose Initial infusion dose: 0.1 μg/kg/minute iv…

…5 to 8 hours Delivery IV Dose 1.25 to 5 mg IV followed by 2.5–15 mg IV every 3 to 6 hours…

…action 1 to 2 minutes Duration of action 10 to 30 minutes Delivery IV Dose Bolus injection : 5 to 15 mg every 5 to 15…

…to apolipoprotein(a). The length of apolipoprotein(a) varies because of genetically determined differences in the number of kringle IV type 2 repeats. Lp(a)…

…patient. Rate control in the stable patient Drug Situation Comment : : : Beta blocker (metoprolol) First choice in most cases The IV dose is titrated slowly. Caution…

…problems, see Warfarin therapy and Opioid therapy in severe pain. Cardiac arrest Drug Adult Child : : : Adrenaline 1 mg IV/IO every 3–5 min. In…

…initial therapy (after corticosteroid) cefotaxime plus ampicillin 3 g × 4 IV plus 3 g × 4 IV 7–21 days depending on the pathogen or meropenem…

…Dofetilide, Ibutilide, Sotalol Class IV Non dihydropyridine L type Ca 2+ channel blockers Diltiazem, Verapamil Singh–Vaughan Williams classification of antiarrhythmic drugs. Bold text indicates…

…minutes Delivery IV (infusion). Dose Initial dose: 1 2 mg/h iv. Increase as necessary. Rapid titration is possible. Maximum dose: 21 mg/h iv…

…Catapress TTS 3 (0.3 mg/24hrs) Dosage in renal failure and renal replacement therapy: Dose as in normal renal function Adverse effects Excessive sedation…

…to onset of action 1 minute Duration of action 20 30 minutes Delivery IV Dose Loading dose: 500 μg/kg bolus over 1 minute…

…<4 hours. Delivery IV or IM. Dose Injections • IV: 10–40 mg every 4–6 hours • IM: 10–20 mg every 4–6 hours. Infusion…

…effect, and significant individual variations in its effect. Drug Enalaprilat Brand names Vasotec IV ® Indications Hypertension and hypertensive emergency. Acute left ventricular failure. Mechanism…

…mg every 10 minutes to a total dose of 300 mg. Infusion regime : • 0.5–2 mg/minute IV infusion. Higher doses are sometimes required…

…to onset of action 5 to 15 minutes Duration of action 1.5 to 5 hours Delivery IV Dose 5–15 mg/hour IV infusion…

…to onset of action 2 to 5 minutes Duration of action 5 to 10 minutes Delivery IV Dose Initial infusion dose: 5 μg/min…

…30 seconds to 1 minute Duration of action 1 to 10 minutes Delivery IV Dose Infusion: Starting dose: 0.25 to 0.5 μg…

…to initiating therapy with the patient hospitalized and monitored for at least several days. Intravenous Loading For emergencies requiring rapid loading and effect, IV amiodarone…

…Dofetilide, Ibutilide, Sotalol Class IV Non dihydropyridine L type Ca 2+ channel blockers Diltiazem, Verapamil Singh–Vaughan Williams classification of antiarrhythmic drugs. Bold text indicates…

…effect, and significant individual variations in its effect. Drug Enalaprilat Brand names Vasotec IV ® Indications Hypertension and hypertensive emergency. Acute left ventricular failure. Mechanism…

…Reversal in major bleeding Drug Reversal : : Warfarin Prothrombin complex concentrate (dose by INR and weight) plus vitamin K 10 mg IV Dabigatran Idarucizumab (Praxbind) Apixaban…

…hyoid, 2 fingerbreadths from hyoid to the upper border of the thyroid cartilage M allampati Class III–IV indicates increased risk O bstruction/Obesity Stridor…

…controlled. Petroleum jelly gauze often gives better pressure but requires more experience and hurts more: consider analgesia (fentanyl 0.5–1 µg/kg IV). Grasp…

…Dobutamine Cardiogenic shock Bradycardia (second line therapy) Stress testing (due to induced increase in myocardial O 2 consumption) Regular : 2.0–20 μg/kg…

Info [calc_vernakalant] Indications for vernakalant Vernakalant (Brinavess) is indicated in adults for chemical conversion of recent onset atrial fibrillation to sinus rhythm. Vernakalant is…

…class II–IV HFrEF. Advanced or refractory heart failure should be considered when there is recurrent clinical deterioration despite careful follow up and appropriate therapy…

…Hypersensitivity to adenosine. Administration Normal route : Peripheral intravenous (IV). Alternative route : Central venous administration of adenosine is suitable in the intensive care unit or coronary…

…Confusion Abdominal pain Hypotension Arrhythmias and ECG changes Cardiac arrest Treatment Furosemide 1 mg/kg IV. Hydrocortisone 300 mg IV. Pamidronate 30 90 mg IV…

…Dobutamine Cardiogenic shock Bradycardia (second line therapy) Stress testing (due to induced increase in myocardial O 2 consumption) Regular : 2.0–20 μg/kg…

…order to evaluate ventricular function, since it may affect the choice of device therapy and also suggest whether other interventions (e.g. heart failure management…

…C Blood samples Management Recommendation Level of evidence Serum biomarkers of myocardial infarction (troponin) should be sampled as early as possible without delaying reperfusion therapy…