…melanoma (a pigmented longitudinal nail band that is widening, with pigment in the cuticle — Hutchinson's sign). An open fracture of the distal phalanx with…

…padding, folds and lumps are the commonest cause of pressure sores. 4. Dip the plaster in tepid water and squeeze out the excess without wringing…

…to three fold greater prevalence of asymptomatic atherosclerotic cardiovascular disease (ASCVD) than the general population. The evidence for premature atherosclerosis is particularly strong in RA…

…may also contribute to stroke in patients with AF. Stroke risk is heterogeneous and is determined principally by the patient’s underlying clinical risk factors…

…3 fold higher in healthy elderly compared with healthy young individuals. Similarly, subjects with severely reduced glomerular filtration rate (GFR) have up to 3 fold…

…contact an ophthalmologist urgently . A positive Seidel's sign. A foreign body centrally in the visual axis requiring an operating microscope. Relative: A patient who…

…serum concentration. Alkalinisation increases renal elimination several fold and at the same time reduces the passage of salicylate into the central nervous system. Contact your…

…associated with reductions in sudden cardiac death and atrial fibrillation. Dietary quality also affects energy balance. Highly processed foods may promote greater ad libitum intake…

…condition. It is associated with a two to four fold increase in lifetime cardiovascular disease (CVD) risk and approximately doubles cardiovascular risk on average. Its…

…rapidly. Rapid enlargement is defined in the source recommendations as at least 10 mm per year or at least 5 mm over 6 months. Such…

…CAD. Risk stratification : Myocardial perfusion imaging is valuable for assessing the risk of future cardiac events in patients with known CAD or after myocardial infarction…

…to six fold higher in affected adults. True, apparent, and pseudo resistant hypertension The term resistant hypertension should be reserved for patients in whom the…

…constitutes a major clinical problem. It can manifest as an increase in the frequency of a pre existing arrhythmia, the sustenance of a previously non…