Articles & courses

Articles
Skin biopsy — punch, shave and excision

…a biopsy for direct immunofluorescence). Suspected cutaneous vasculitis, lymphoma or granulomatous disease. A treatment resistant rash without a definite diagnosis. Choice of technique Diagnostic question…

Injection technique — intramuscular, subcutaneous and intradermal

…done wrongly. The two commonest errors are that an intramuscular injection in fact ends up subcutaneously in a patient with a high BMI, and that…

Inclisiran and Emerging Lipid-Lowering Agents

…PCSK9 synthesis decreases circulating PCSK9, increases the availability of hepatic low density lipoprotein cholesterol (LDL C) receptors at the cell surface, and thereby enhances removal…

Cardiac arrest due to pneumothorax

…Clinically, patients may present with: Absent breath sounds on the affected side Crepitus Subcutaneous emphysema Hypotension Hypoxia Mediastinal shift, with potential tracheal deviation to the…

Bone marrow aspiration and biopsy

…Indications Unexplained cytopenia in one or more cell lines. Suspected acute leukaemia, myelodysplastic syndrome or myeloproliferative neoplasm. Work up and staging of lymphoma and myeloma…

ACE Inhibitor Cough and Angioedema: Practical Management

…dependent. Similarly, angioedema occurring in the setting of ACE inhibitor therapy is bradykinin mediated rather than mast cell mediated, distinguishing it from classic allergic reactions…

Performing Echocardiographic Examinations

…some pressure when holding the transducer against the skin. Patients with extensive subcutaneous fat require harder pressure. Orientation index marker All ultrasound transducers have an…

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