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Acute Limb Ischaemia: Recognition and Urgent Management

…although Doppler examination may detect residual arterial flow in less advanced disease. Clinical manifestations may be relatively modest when collateral circulation is adequate. For example…

PCSK9 Inhibitors: Indications, Efficacy and Access

Cardiology Pharmacology & dosing Definition and Pathophysiology Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a hepatic protein that regulates the availability of the low density…

Bone marrow aspiration and biopsy

…with stylet) and a Jamshidi type biopsy needle. Syringes: a small 5–10 mL syringe for the first aspirate, larger syringes for the tube specimens…

Dix–Hallpike test and Epley manoeuvre

…possible residual unsteadiness. No hearing loss, tinnitus or neurological deficits. In horizontal positional vertigo (lateral semicircular canal) the supine roll test is used for diagnosis…

Edrophonium test

…suction, a bag and mask, and access to equipment and competence for advanced life support in the room. Two people: one who injects and monitors…

Urinary catheterisation

…retention. Chronic urinary retention with renal impairment or a large residual volume. A need for accurate measurement of urine output in a critically ill patient…

Cardiac Rehabilitation After Myocardial Infarction

…function Residual ischaemic myocardium Ventricular arrhythmic risk Cardiovascular risk factors Functional capacity and degree of deconditioning Psychological status, including depression and anxiety Social support and…

Colchicine and Anti-inflammatory Therapy in Coronary Disease

…previous acute coronary syndrome. The available evidence supports consideration of low dose colchicine as an adjunct to, rather than a replacement for, established secondary prevention…

Complete Versus Culprit-Only Revascularization in Acute Coronary Syndrome

…additional non infarct related lesions. Culprit only revascularization treats the artery responsible for the acute clinical event during the index procedure. Complete revascularization aims to…

Drug-Eluting Coronary Stents: Evolution, Evidence and Stent Choice

…principally by neointimal hyperplasia. Contemporary DES combine a metallic scaffold, a polymeric or polymer free drug delivery system, and an antiproliferative agent. Their development has…

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