…whereas disruption of the adventitia can result in rupture. An alternative proposed mechanism is primary rupture of the vasa vasorum, followed by disruption of the…

…weeks after infarction. Predisposing features Risk features vary by lesion but include: Older age. Female sex. Hypertension. Absence of an adequate collateral circulation. A first…

…The transition from a quiescent plaque to a highly thrombogenic surface occurs via three primary mechanisms: Plaque Rupture: Accounting for 60 70% of ACS presentations…

…4745 patients within 30 days of myocardial infarction. Participants received colchicine 0.5 mg once daily or placebo. The primary composite outcome included cardiovascular death…

…screening consists of the smear, not of the examination itself. Cervical cancer screening in Sweden Since 2017, HPV testing has been the primary screening test…

…inflammatory activity of the plaque that dictate clinical risk [8] . Plaques The architecture and composition of the atherosclerotic plaque are the primary determinants of its…

…potassium, and resistant to suppression by sodium loading. It is the most common form of secondary hypertension. Aldosterone acts principally through the mineralocorticoid receptor (MR)…

…after onset: routine primary PCI should be considered in otherwise stable patients. More than 48 hours after onset: routine PCI of an occluded infarct related…

…soon after treatment is initiated. Reported increases include: Approximately 43% increase in major bleeding in a meta analysis of primary prevention trials. Approximately 58% increase…