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Alcohol and Cardiovascular Disease

…in myocardial oxygen consumption associated with exercise. Chronic myocardial injury Long term heavy consumption can produce a cardiomyopathy, although the exact exposure threshold and duration…

Gastric lavage and activated charcoal

…funnel or a lavage system, lukewarm fluid (tap water for adults, isotonic saline for children), a collecting vessel, a bite block, and powerful suction with…

Myocardial ischemia and infarction: lack of oxygen or imbalance between supply/demand

…conceptual and lacks scientific evidence. As suggested by Heusch, [1] this may be due to the fact that interventions that appear to modify oxygen demand…

Oxygen therapy

… the patient can eat and talk. Flows above 6 L/min dry the mucosa without delivering more oxygen Simple face mask 5–10 L/min…

Cardiac arrest due to hypoxia and asphyxia

…reduced partial pressure of oxygen in the blood. Asphyxia is characterized by insufficient ventilation, leading to hypoxia. Etiologies of hypoxic cardiac arrest : Trauma and injuries :…

Circulatory and haemodynamic parameters

…SVR = 80 × (MAP − CVP) / CO PVR = 80 × (mean PA − PCWP) / CO Oxygen delivery (DO₂) = CO × (1.34 × Hb × SaO₂ + 0.003 × PaO₂)…

Massive haemorrhage and transfusion: quick reference

…determines the outcome. Transfusion restores circulating volume, oxygen transport and haemostatic capacity, but it cannot compensate for an uncontrolled source of bleeding. Minimise the time…

Type 2 Myocardial Infarction: Mechanisms and Management

…advised in interpreting it without corroborating evidence of a coronary mechanism. The clinical context and the underlying mechanism of the oxygen supply/demand imbalance must…

CPAP and non-invasive ventilation (NIV)

…Copious secretions without an effective cough. Choice of method and settings Condition Method Starting pressure Escalation Oxygen target : : : : : Cardiogenic pulmonary oedema CPAP 5–7.5…

Sepsis and septic shock: quick reference for the first hour

…three hours. The evidence for an absolute one hour requirement is clearest in septic shock and less certain in sepsis without shock [3,4]. The…

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