…is limited. A Cochrane review found insufficient randomised evidence to determine which agent is best. The choice is therefore governed chiefly by the target organ…

…international guidelines on neutropenic fever [2]. The direct evidence for exactly one hour in neutropenic fever is limited, but delayed antibiotics are associated with a…

…however, incorporates overall cardiovascular risk, comorbidity and hypertension mediated organ damage (HMOD), rather than relying exclusively on the office pressure value. Blood pressure terminology Systolic…

…in a formally unimpeachable way, and that the donor's organs are maintained physiologically for as long as the assessment takes. The task of the…

Kardiologi Akutsjukvård Lathundar Key message The distinction that determines management is: is there acute hypertension mediated organ damage or not? A single blood pressure value…

Cardiology Emergency medicine Definition and Pathophysiology A hypertensive emergency is severe blood pressure elevation accompanied by acute hypertension mediated target organ damage (HMOD). The European…

Critical care Myocardial ischemia and infarction Definition and Pathophysiology Cardiogenic shock is a state of inadequate tissue and end organ perfusion caused by cardiac insufficiency…

…wait for complete diagnostic certainty. Sepsis is defined as life threatening organ dysfunction caused by a dysregulated host response to infection. Clinically this usually corresponds…

…defined as significantly elevated blood pressure (systolic pressure ≥180 mmHg and/or diastolic pressure ≥120 mmHg) with concurrent signs of acute organ damage or failure…

…manipulate systemic and pulmonary vascular resistance, and restore adequate end organ perfusion. Dobutamine is a synthetic catecholamine that functions as an agonist of both beta1…

…defined as significantly elevated blood pressure (systolic pressure ≥180 mmHg and/or diastolic pressure ≥120 mmHg) with concurrent signs of acute organ damage or failure…

…become cheaper, more portable, more powerful, equipped with an increasing number of methods to interrogate organ structure and function. Ultrasound imaging, including echocardiography, has become…

…started . Suspected white coat hypertension: raised office blood pressure without organ damage. Suspected masked hypertension: normal office blood pressure but organ damage or high risk…

…impaired consciousness or new onset marked weakness rapidly progressive symptoms from several organ systems severe abdominal pain or repeated vomiting after probable allergen exposure sudden…

…systole and diastole. It is a critical parameter in cardiovascular physiology, providing insight into the perfusion pressure experienced by organs and tissues. Clinically, MAP is…

…50 beats per minute in the first 4 to 6 hours after an acute infarction—patients may develop hypotension and signs of end organ hypoperfusion…

…categorization is applicable Moderate or severe chronic kidney disease (CKD) Hypertension mediated organ damage (HMOD) Probable or definite familial hypercholesterolaemia Other markedly abnormal single risk…

…characterized by new onset hypertension after 20 weeks, generally accompanied by proteinuria or evidence of maternal organ involvement. Proteinuria is defined as urinary protein excretion…

…present Factors that may be contributing to elevated blood pressure Other cardiovascular risk factors and relevant comorbidities Evidence of hypertension mediated organ damage Existing cardiac…

…increase. Hypertensive crisis Hypertensive urgency: markedly raised pressure without organ involvement — lower it orally over days. Hypertensive emergency: raised pressure with acute organ damage (encephalopathy…

…progression risk, increased by proteinuria 3a 45–60 mL/min/1.73 m² Cardiovascular disease or other organ damage may be present Moderate progression risk;…

…cannot be pursued. Patients receiving digoxin may present with symptoms of digitalis toxicity, which manifests across multiple organ systems. Non cardiac symptoms include headache, nausea…

…or end stage renal failure Consider renal replacement therapy Hypoperfusion with persistent organ injury Consider mechanical circulatory support Refractory advanced disease Consider palliative care Right…

…and kidney disease All patients with diabetes should be assessed for: ASCVD Severe target organ damage (TOD) HF AF CKD Other clinically relevant cardiovascular disease…

…preload, diminished stroke volume, and subsequently lower blood pressure and reduced organ perfusion. Left ventricular dilation occurs with ensuing decline inleft ventricular ejection fraction (LVEF)…

…same Virchow who unraveled thrombosis). He used te term to describe a reduction of blood flow to tissues and organs. A few decades later Cohnheim…

…red marrow is abundant, and the distance to vessels and abdominal organs is large. The sternum may be used for aspiration when the iliac crest…

…Subclinical cerebral injury may contribute to vascular dementia, and thromboembolism may affect organs other than the brain. Patients with AF in the setting of ACS…

…direct biologic effect. BNP and NT proBNP have different clearance characteristics. Both undergo passive clearance through highly perfused organs, including the kidneys. BNP is additionally…

…Such thrombi may leave the appendage and enter the systemic circulation which causes thromboembolic occlusions of arteries in the brain, limbs or other organs. However…

…cerebral, and pulmonary tissue. Chest compressions produce perfusion of vital organs by increasing the pressure in the atria, ventricles and large vessels. This results in…