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Foreign body in the ear and nose

…small, smooth or transparent object lying posteriorly or superiorly. Attempts already made and failed elsewhere. A child who cannot be kept still without sedation. Suspected…

Ankle-brachial index (ABI)

…rested lying down for at least 10 minutes in a room at a comfortable temperature — a cold foot gives falsely low pressures. No smoking or…

LDL Cholesterol Targets Across Cardiovascular Risk Categories

…years without diabetes and with LDL C between 70 and 189 mg/dL, 10 year risk of a first hard ASCVD event—fatal or nonfatal…

Circulatory and haemodynamic parameters

…in a ventilated patient in sinus rhythm without spontaneous breathing, passive leg raising with an increase in stroke volume 10%, or inferior vena cava variability …

A new ECG biomarker for sudden cardiac death

…morphology, which replaces the sharp negative S wave seen in the low risk beat — the previously undescribed biomarker identified by the deep learning model. Predicting…

Bempedoic Acid: Evidence and Clinical Use

…lipid lowering agent used to reduce low density lipoprotein cholesterol (LDL C), particularly when statins cannot be tolerated or when LDL C remains above goal…

Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…In untreated HeFH, CAD commonly develops during the third or fourth decade in males and approximately 10 years later in females. Untreated HoFH is associated…

PCSK9 Inhibitors: Indications, Efficacy and Access

…Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a hepatic protein that regulates the availability of the low density lipoprotein receptor (LDL receptor) on hepatocytes…

Biventricular hypertrophy ECG and clinical characteristics

…left and right ventricle is rather common. The ECG has low sensitivity with respect to detecting biventricular hypertrophy. This is because the strong and oppositely…

Exercise stress test on cycle ergometer

…W and increase by 10–25 W every minute, or by 25–50 W every third minute. Adjust so that the total exercise time is…

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