…monitoring Parameter Target Comment : : : Intracranial pressure (ICP) < 22 mmHg The treatment threshold in traumatic brain injury Cerebral perfusion pressure (CPP) 60–70 mmHg CPP…

…remains unknown ( Guildner et al ). Jaw thrust is preferred if there is suspicion of cervical spine injury, in which scenario head tilt chin lift should…

…Efficient CPR generates approximately 25% of normal cardiac output, which postpones or mitigates cerebral injuries. No flow time and low flow time are critical parameters…

…hypoxia, hypoglycaemia, circulatory failure, sepsis, stroke, intracranial haemorrhage, seizure, poisoning and severe withdrawal. 4. Establish whether the condition is new or clearly worse than baseline…

…a rising blood pressure with bradycardia. A known or suspected intracranial space occupying lesion with mass effect and midline shift. Ongoing anticoagulant treatment or marked…

…abdominal or thoracic surgery 1 month Neurosurgery or an intracranial aneurysm Contact the responsible specialist An aortic aneurysm 6 cm Relative — avoid forced manoeuvres An…

…coagulopathy. Severe uncontrolled hypertension. Recent intracranial haemorrhage without a fresh assessment of benefit and risk. An inability to attend for sampling and follow up — relative…

…Increased intra ocular pressure in patients with glaucoma. Caution Used cautiously in patients with glaucoma or increased intracranial pressure. Fenoldopam doses and administration in hypertension.

…any of the excipients. Active pathological bleeding , such as gastrointestinal bleeding or intracranial hemorrhage. History of stroke or transient ischemic attack (TIA). Severely impaired liver…

…Contraindications Hypersensitivity to the active substance or any excipient. Active bleeding. Previous intracranial hemorrhage. Severe liver impairment. Concurrent administration of ticagrelor with strong CYP3A4 inhibitors…