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Cardiovascular Risk in Women: Sex-Specific Factors

…heart failure and one in five for stroke. Sex and gender are distinct but interacting determinants of cardiovascular health. Sex refers principally to biological characteristics…

Cardiac arrest due to hypoxia and asphyxia

CPR Hypoxia and asphyxiation Hypoxia refers to a reduced partial pressure of oxygen in the blood. Asphyxia is characterized by insufficient ventilation, leading to hypoxia…

Anticoagulants: quick reference for dosing, renal adjustment and reversal

…months 15 30 Dabigatran contraindicated. The other DOACs are possible according to FASS, but the documentation is insufficient; check more frequently. Warfarin is often preferable…

Arterial line

…Contraindications Infection, burn or trauma over the insertion site. Insufficient collateral circulation to the hand. Vascular disease in the limb: marked peripheral arterial disease, Raynaud…

Bone marrow aspiration and biopsy

…involvement. Work up of unexplained iron, B12 or folate deficiency when blood tests are insufficient. Contraindications Severe coagulopathy or ongoing anticoagulation — correct this first . Thrombocytopenia…

CPAP and non-invasive ventilation (NIV)

…Atelectasis and postoperative hypoxaemia. Hypoxaemic failure where high flow nasal oxygen is insufficient and the carbon dioxide is normal. Bilevel NIV: Acute exacerbation of COPD…

Targeted temperature management after cardiac arrest

…in patients who remain unconscious. The evidence is insufficient to recommend for or against active cooling to 32–36 °C. The HYPERION result means that…

🟠 ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) Bleeding Risk Score

…reduced hemoglobin/hematocrit, bleeding history, insufficient kidney function, and treatment with antiplatelet agents. Research indicates that the ORBIT score may offer better discrimination and calibration…

🟠 Lipid lowering therapy after ACS

…C ≥ 1.4 mmol/L (55 mg/dL): • Add ezetimibe (if not already added earlier). • Add a PCSK9 inhibitor (if statin + ezetimibe combination is insufficient).

Invasive Coronary Angiography: Indications and Vascular Access

…do not always correspond. Visual estimation of luminal narrowing may therefore be insufficient when deciding whether an intermediate lesion should be revascularized. Coronary pressure assessment…

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