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Chest Pain in the Emergency Department: Diagnostic Pathways

Emergency medicine Myocardial ischemia and infarction Definition and Clinical Framework Chest pain is a broad clinical syndrome rather than a narrowly defined symptom. It includes…

Hypertensive Emergency and Urgency: Differentiation and Treatment

Cardiology Emergency medicine Definition and Pathophysiology A hypertensive emergency is severe blood pressure elevation accompanied by acute hypertension mediated target organ damage (HMOD). The European…

Acute Coronary Syndrome: Definitions and Initial Triage

Emergency medicine Myocardial ischemia and infarction Definition and pathophysiology Acute coronary syndrome (ACS) comprises a spectrum of clinical presentations caused by suspected acute myocardial ischaemia…

Differential Diagnosis of Chest Pain: A Clinical Overview

Emergency medicine Lathundar Differential Diagnosis of Chest Pain: A Clinical Overview The evaluation of acute chest discomfort requires a systematic differential diagnosis, as the syndrome…

Right Ventricular Infarction: Recognition and Haemodynamic Management

Emergency medicine Myocardial ischemia and infarction Definition and pathophysiology Right ventricular infarction (RVI) is myocardial necrosis involving the right ventricle, most often occurring in association…

STEMI: Primary PCI and System-of-Care Time Targets

Emergency medicine Myocardial ischemia and infarction Definition and Pathophysiology ST segment elevation myocardial infarction (STEMI) is an acute myocardial infarction associated with a working diagnosis…

Acute Limb Ischaemia: Recognition and Urgent Management

Clinical medicine Emergency medicine Definition and pathophysiology Acute limb ischaemia (ALI) is an abrupt reduction in arterial perfusion of an upper or lower limb that…

High-Sensitivity Troponin: 0/1-Hour Rule-In and Rule-Out Algorithms

Clinical chemistry & laboratory medicine Emergency medicine Myocardial ischemia and infarction Definition and Pathophysiological Basis High sensitivity cardiac troponin (hs cTn) assays detect circulating troponin released…

Acute Aortic Syndromes: Intramural Haematoma and Penetrating Atherosclerotic Ulcer

Cardiology Emergency medicine Definition and Pathophysiology Acute aortic syndromes comprise classic aortic dissection, intramural haematoma (IMH), and penetrating atherosclerotic ulcer (PAU). Aortic dissection accounts for…

Acute Pulmonary Embolism: Risk Stratification and Reperfusion

Cardiology Emergency medicine Definition and pathophysiology Acute pulmonary embolism (PE) is classified according to haemodynamic status, clinical severity, evidence of right ventricular (RV) dysfunction, and…

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