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Skin biopsy — punch, shave and excision

…A pot of 4 % formalin, and for immunofluorescence Michel's medium or saline according to local procedure. Photograph and draw in the site before the…

Leg ulcers — wound debridement and compression therapy

…arterial insufficiency can cause necrosis and, in the worst case, amputation. The decisive step is therefore not the choice of dressing but the ankle brachial…

Cryotherapy of skin lesions

…lesion of uncertain diagnosis. A lesion in which histology is needed for management. Cryoglobulinaemia, cold agglutinin disease, cold urticaria. Relative: Basal cell carcinoma and squamous…

Primary Aldosteronism: Screening and Management

…and induces expression of aldosterone responsive genes. Although the kidney is a major target—where MR activation promotes sodium transport—MRs are also present in…

Pulmonary stenosis

…disease : Carcinoid syndrome is a paraneoplastic syndrome that occurs due to carcinomas secreting kallikrein and serotonin. In the heart, this can lead to thickening of…

Pulmonary regurgitation

…and RVOT (right ventricular outflow tract) become dilated, which further agravates the regurgitation. The proximal portion of the pulmonary artery may also be dilated in…

Tricuspid regurgitation (TR/TI)

…of rheumatic valvular disease. The regurgitation is considered severe if the tricuspid annulus diameter is 4 cm. Severe tricuspid regurgitation results in right ventricular and…

Mitral valve stenosis

…the right ventricle and right atrium, leading to right heart hypertrophy, dilation and ultimately right heart failure. Echocardiography in mitral stenosis Echocardiographic assessment of mitral…

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