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Skin biopsy — punch, shave and excision

…A pot of 4 % formalin, and for immunofluorescence Michel's medium or saline according to local procedure. Photograph and draw in the site before the…

Leg ulcers — wound debridement and compression therapy

…arterial insufficiency can cause necrosis and, in the worst case, amputation. The decisive step is therefore not the choice of dressing but the ankle brachial…

Cryotherapy of skin lesions

…lesion of uncertain diagnosis. A lesion in which histology is needed for management. Cryoglobulinaemia, cold agglutinin disease, cold urticaria. Relative: Basal cell carcinoma and squamous…

Primary Aldosteronism: Screening and Management

…and induces expression of aldosterone responsive genes. Although the kidney is a major target—where MR activation promotes sodium transport—MRs are also present in…

Pulmonary stenosis

…PASP is an independent predictor of survival and for elevated left ventricular filling pressures (Lam et al). PASP is elevated in pulmonary arterial hypertension (PAH…

Pulmonary regurgitation

…of the pulmonary valve Idiopathic pulmonary artery dilation Pulmonary regurgitation results in right ventricular volume overload, which gradually causes right ventricular failure. The ventricle and…

Tricuspid regurgitation (TR/TI)

…of rheumatic valvular disease. The regurgitation is considered severe if the tricuspid annulus diameter is 4 cm. Severe tricuspid regurgitation results in right ventricular and…

Mitral valve stenosis

…gradually leads to atrial hypertrophy and dilation. Atrial dilation causes a significantly increased risk of atrial fibrillation. The increase in left atrial pressure may also…

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