Procedurer Warfarin has a narrow therapeutic index, a half life of several days and more than a hundred clinically relevant interactions. What determines whether the…

…to estimate the risk of major bleeding in patients with atrial fibrillation (AF) undergoing anticoagulation therapy, particularly with warfarin. Developed from the ATRIA study cohort…

…Reversal in major bleeding Drug Reversal : : Warfarin Prothrombin complex concentrate (dose by INR and weight) plus vitamin K 10 mg IV Dabigatran Idarucizumab (Praxbind) Apixaban…

…a fuller account of two of the commonest acute drug problems, see Warfarin therapy and Opioid therapy in severe pain. Cardiac arrest Drug Adult Child : : …

…Recommendation Evidence 0 No treatment Low No treatment High 1 Oral anticoagulation (warfarin or NOAK 1 is considered for male patients with a score of…

…Decontamination Disrobe the patient of any attire possibly contaminated with the toxicant. Irrigate skin and eyes using saline solution (NaCl) if suspected of toxin exposure…

…without delay, in any of the following: A systolic blood pressure < 90 mmHg caused by the arrhythmia. Ongoing myocardial ischaemia with chest pain and…

…energy and is difficult to terminate pharmacologically. Ectopic atrial tachycardia or SVT that has not been terminated by vagal manoeuvres, adenosine or rate controlling drugs…

…in pregnancy and an alternative in cancer associated thrombosis. Warfarin in antiphospholipid syndrome and in marked renal failure. Duration of treatment: at least 3 months…

…channel blockers, colchicine, ciclosporin, warfarin and grapefruit juice. Gemfibrozil should not be combined with statins because it alters statin absorption, hepatic uptake and disposition. Clinical…