…clear reduction or the last intake Common clinical picture : : 4 to 12 hours Tremor, sweating, anxiety, insomnia, tachycardia, hypertension, headache, nausea and vomiting 8 to…

…skin reactions (e.g., Stevens Johnson syndrome, toxic epidermal necrolysis, DRESS syndrome) have been rarely reported with acetylsalicylic acid. Discontinue acetylsalicylic acid at the first…

…3] . Once trapped within the subendothelial space, LDL C particles undergo oxidative modification by reactive oxygen species (ROS) and enzymes such as myeloperoxidase and lipoxygenase…

…reduced systemic vascular resistance. The resulting mild reduction in blood pressure is often accompanied by a compensatory rise in cardiac output. Although these changes are…

…complicated topic. The term ischemia was coined in 1858 by Virchow (the same Virchow who unraveled thrombosis). He used te term to describe a reduction…

…Severe elevation Acute HMOD Present Absent clinically Symptoms Often present and related to the affected organ May be absent or nonspecific Treatment setting Usually hospital…

…therapeutic to toxic windows, and its routine use in adult patients is generally discouraged. However, it retains a specific niche in contemporary cardiovascular pharmacotherapy. The…

…given after the ingestion of a potentially toxic dose of a substance that binds to charcoal, when it can be given early and the patient…

…control centre is the authoritative local source for the current indication, dosing, sampling and duration of treatment. International guidelines must be adapted to the antidotes…

…to diagnostic spirometry with a reversibility test. At follow up during ongoing treatment, the test is performed on the usual medication — note this in the…

…renal function occurring after exposure to iodinated contrast media, particularly during cardiovascular angiography, computed tomography, or percutaneous coronary intervention. The preferred terminology is contrast associated…

…sedatives Trauma and medication directed workup This corresponds to the principles of TiTrATE, in which Timing, Triggers And Targeted Examination guide the diagnostic process [1]…

…transiently toxic concentrations, adenosine requires a rapidly delivered bolus to achieve sufficiently high concentrations at its clinical site of action—the coronary artery perfusing the…

…directly toxic to cardiomyocytes, inducing the elaboration of high levels of natriuretic peptides and cardiac troponin [19]. ATTR Amyloidosis: This form arises from the misfolding…

…reveal that up to 30 40% of "idiopathic" cases harbor a genetic basis. Truncating variants in the TTN gene (titin) are the most common genetic…

…lactate, acidosis, hypertension and tachycardia are common during a generalised seizure. In prolonged status the initial sympathetic response can give way to hypotension, hypoxia, hypoglycaemia…

…contaminated with the toxicant. Irrigate skin and eyes using saline solution (NaCl) if suspected of toxin exposure. Gastrointestinal lavage is infrequently employed due to aspiration…

…by irregular (polymorphic) QRS complexes that appear to twist around the isoelectric baseline. The risk of ventricular fibrillation is very high during torsade de pointes …

…Syndrome]); blocking AV node conduction may result in accelerated transmission of atrial impulses to the ventricles and thus ventricular fibrillation and cardiac arrest. High degree…

…elusive. This is a rather complex topic that is only of relevance to researchers in electrophysiology and arrhythmology. Regarding the risk of ventricular fibrillation, it…

…if the QRS complexes are wide there is a risk of distal block which may progress to more advanced block (second or third degree AV…

…during systole showing apical ballooning akinesis with basal hyperkinesis in a characteristic takotsubo ventricle. Studies from the US and Japan has estimated that up to…