…males and 40 g daily in females as capable of causing cardiomyopathy. Several mechanisms contribute: Direct toxic effects on cardiomyocytes Disruption of intracellular signalling and…

…electrophysiologic effects on the His Purkinje system and ventricular muscle are minimal, except in cases of toxic concentrations. In most patients, the sinus rate and…

…and other NSAIDs: Increased risk of gastrointestinal bleeding when combined with acetylsalicylic acid. Uric acid excretion agents (e.g., probenecid): Salicylates counteract the effect of…

…the sinus and atrioventricular (AV) nodes. In addition to these direct effects, adenosine antagonizes catecholamine stimulated adenylate cyclase. This inhibition decreases the accumulation of cyclic…

…The kidney is particularly vulnerable to toxic injury because of its high blood flow and the concentration of filtered substances along the nephron as water…

…Toxic and infiltrative causes are increasingly recognized. The burgeoning field of cardio oncology has highlighted the cardiotoxic effects of anthracyclines, HER2 inhibitors (trastuzumab), and immune…

…treatment effect and of disease progression. Assessment of pulmonary involvement in systemic disease, for example rheumatoid arthritis or scleroderma, and during treatment with pulmonary toxic…

…This side effect lasts a few seconds. Case reports have indicated that the risk of high degree AV block and ventricular arrhythmias is greater in…

…Table 1 delineates substances for which specific antidotes are available. The detrimental effects of these substances can potentially be reversed if interventions are promptly instituted…

…with a relatively clear level of consciousness and preserved orientation 12 to 48 hours Withdrawal seizures, usually generalised tonic clonic and sometimes several within a…

…risk of ventricular arrhythmias. Corrected QT Interval (QTc interval) The QT interval varies inversely with heart rate; it shortens at higher heart rates and lengthens…

…ethylene glycol Corrosive substances Strong acids and alkalis Petroleum products Lamp oil, petrol, turpentine, lighter fluid Others Cyanide, boric acid, fluoride Preparation and equipment Medicinal…

…in cardiogenic toxic shock D Plasma glucose immediately. Assess the level of consciousness, the pupils, tone, clonus and seizures. Give glucose in hypoglycaemia and a…

…but only if the examiner is trained. Brief attacks triggered by the position of the head relative to gravity: perform Dix Hallpike and, if needed…

…toxic to cardiomyocytes, inducing the elaboration of high levels of natriuretic peptides and cardiac troponin [19]. ATTR Amyloidosis: This form arises from the misfolding of…

…cap. The LRNC is a highly toxic, pro thrombotic milieu composed of extracellular cholesterol crystals, apoptotic and necrotic macrophage debris, and abundant tissue factor [9] …

Neurologi Akutsjukvård Lathundar Definition and aims of treatment Convulsive status epilepticus in adults is present with: an ongoing generalised tonic clonic seizure lasting at least…

…discussion: the ECG blog Myocardial ischemia and infarction Myocardial ischemia The definition of ischemia may appear trivial but it is actually a very complicated topic…

…dizziness, and neurological deficits. Neurological involvement Hypertensive encephalopathy may present with somnolence, lethargy, tonic–clonic seizures, cortical blindness, and, in advanced cases, loss of consciousness…

…elusive. This is a rather complex topic that is only of relevance to researchers in electrophysiology and arrhythmology. Regarding the risk of ventricular fibrillation, it…

…AV block and wide QRS complexes. Treatment of first degree AV block Refer to Management of Atrioventricular (AV) Blocks https://ecgwaves.com/topic/av block…

…This topic is still under investigation. A number of plausible mechanisms have been suggested. Among them are coronary artery vasospasm, dysfunctional capillary function and catecholamine…