…Interactions Pharmacodynamic interactions Anticoagulants, thrombolytics, or other platelet aggregation inhibitors: Salicylates inhibit platelet function and enhance the effect of anticoagulants, increasing bleeding risk. Monitor coagulation…

…electrophysiologic effects on the His Purkinje system and ventricular muscle are minimal, except in cases of toxic concentrations. In most patients, the sinus rate and…

…males and 40 g daily in females as capable of causing cardiomyopathy. Several mechanisms contribute: Direct toxic effects on cardiomyocytes Disruption of intracellular signalling and…

…This side effect lasts a few seconds. Case reports have indicated that the risk of high degree AV block and ventricular arrhythmias is greater in…

…with a relatively clear level of consciousness and preserved orientation 12 to 48 hours Withdrawal seizures, usually generalised tonic clonic and sometimes several within a…

…effects of contrast exposure and other ischaemic or nephrotoxic stresses. The kidney is particularly vulnerable to toxic injury because of its high blood flow and…

…the sinus and atrioventricular (AV) nodes. In addition to these direct effects, adenosine antagonizes catecholamine stimulated adenylate cyclase. This inhibition decreases the accumulation of cyclic…

…or fumes. Preoperative assessment before thoracic or upper abdominal surgery in a patient with known lung disease. Follow up of treatment effect and of disease…

…Toxic and infiltrative causes are increasingly recognized. The burgeoning field of cardio oncology has highlighted the cardiotoxic effects of anthracyclines, HER2 inhibitors (trastuzumab), and immune…

…risk of ventricular arrhythmias. Corrected QT Interval (QTc interval) The QT interval varies inversely with heart rate; it shortens at higher heart rates and lengthens…

…discussion: the ECG blog Myocardial ischemia and infarction Myocardial ischemia The definition of ischemia may appear trivial but it is actually a very complicated topic…

…saline solution (NaCl) if suspected of toxin exposure. Gastrointestinal lavage is infrequently employed due to aspiration risks and inconclusive evidence. However, in cases of iron…

…quantities of an extremely toxic preparation, lavage can be discussed later. Lavage must never be performed routinely in poisoning — it rarely alters the course and…

…in cardiogenic toxic shock D Plasma glucose immediately. Assess the level of consciousness, the pupils, tone, clonus and seizures. Give glucose in hypoglycaemia and a…

…infarction, intoxication, Wernicke's encephalopathy, other central disease Neurological examination, gait and truncal stability, often MRI Episodic triggered vestibular syndrome Brief attacks, usually lasting seconds…

…toxic to cardiomyocytes, inducing the elaboration of high levels of natriuretic peptides and cardiac troponin [19]. ATTR Amyloidosis: This form arises from the misfolding of…

…cap. The LRNC is a highly toxic, pro thrombotic milieu composed of extracellular cholesterol crystals, apoptotic and necrotic macrophage debris, and abundant tissue factor [9] …

Neurologi Akutsjukvård Lathundar Definition and aims of treatment Convulsive status epilepticus in adults is present with: an ongoing generalised tonic clonic seizure lasting at least…

…and drug related presentations Severe hypertension may result from phaeochromocytoma, monoamine oxidase inhibitor crisis, cocaine intoxication, or other sympathomimetic exposure, including methamphetamine. Abrupt withdrawal of…

…elusive. This is a rather complex topic that is only of relevance to researchers in electrophysiology and arrhythmology. Regarding the risk of ventricular fibrillation, it…

…AV block and wide QRS complexes. Treatment of first degree AV block Refer to Management of Atrioventricular (AV) Blocks https://ecgwaves.com/topic/av block…

…This topic is still under investigation. A number of plausible mechanisms have been suggested. Among them are coronary artery vasospasm, dysfunctional capillary function and catecholamine…