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Cardiac arrest during sepsis

…systemic inflammatory response syndrome (SIRS), disseminated intravascular coagulation (DIC), and hypoperfusion manifesting as hypotension. The high mortality associated with sepsis underscores the critical importance of…

Cardiac arrest in hyperthermia and malignant hyperthermia

…to the Systemic Inflammatory Response Syndrome (SIRS). Body temperatures surpassing 40°C (104°F) are potentially hazardous and may precipitate cardiac arrest. The classification of hyperthermia is…

Care after return of spontaneous circulation (ROSC)

…similar to SIRS (systemic inflammatory response syndrome) with risk of disseminated intravascular coagulation, hypotension, impaired vasoregulation, etc. With regard to the underlying cause of cardiac…

Cardiovascular Risk in Women: Sex-Specific Factors

…management, treatment response and outcomes of cardiovascular disease. The biological differences between females and males arise partly from the chromosomal distinction between XX and XY…

ST-Elevation Myocardial Infarction (STEMI): Pathophysiology, Diagnosis, and Management

…progressive, and highly complex lipid driven inflammatory disease of the arterial intima that serves as the fundamental pathophysiological substrate for acute coronary syndromes (ACS), including…

Atherosclerosis: Pathogenesis from Fatty Streak to Plaque Rupture

…sustained inflammatory response. Lipid accumulation, oxidative stress and immune activation progressively alter the local vascular environment. The extracellular matrix is an active component of lesion…

Acute severe asthma in adults: quick reference

…response. First line treatment is oxygen in hypoxaemia, repeated doses of an inhaled short acting β2 agonist, ipratropium in more severe attacks, and a systemic…

Corticosteroids: quick reference for dose equivalents and stress dosing

…proton pump inhibitor with concomitant NSAID use or a history of ulcer, not routinely Infection Consider Pneumocystis prophylaxis with high doses over a long period…

Cardiovascular Risk in Inflammatory and Autoimmune Disease

…population. This excess risk has been documented across a broad range of conditions, including gout, vasculitis, systemic sclerosis, myositis, mixed connective tissue disease, Sjögren syndrome…

Isoprenaline and Dopamine Infusions for Bradycardia

…reversible systemic insults, including hypovolemia, hypoxia, cardiac tamponade, tension pneumothorax, preexisting acidosis, drug overdose, hypothermia, and hyperkalemia. When bradycardia occurs in the context of inflammatory…

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