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Coronary Artery Calcium Scoring: Prognostic Use in Practice

…likely to rupture than non calcified, lipid rich plaque. CAC nevertheless serves as a marker of the broader atherosclerotic process, including non calcified plaques that…

Familial and Genetic Screening in Premature Cardiovascular Disease

…and MYBPC3. Approximately 40–60% of tested patients have a single variant identified as the cause of disease, although the yield varies by cohort. A…

Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…social and multigenerational family history. The evaluation should establish: The magnitude of untreated LDL C elevation. The presence and age of onset of premature CAD…

Statin Intolerance and Statin-Associated Muscle Symptoms

…a personal or family history of muscle disorders Acute infection Renal or hepatic impairment Hypothyroidism Vitamin D deficiency Concomitant interacting medications The SLCO1B1 rs4149056 polymorphism…

Lipoprotein(a): Measurement and Clinical Implications

…may influence management. A single measurement is generally sufficient because Lp(a) is genetically determined and does not fluctuate substantially over the lifetime. A repeat…

Eye examination and corneal foreign body

…from the conjunctiva or the cornea. Never use a cotton bud on an embedded corneal foreign body — it scrapes away a large area of epithelium…

Laryngeal mask and difficult airway

…Contraindications The laryngeal mask is a compromise and does not protect the airway completely. Relative contraindications: A high risk of aspiration: a non fasted patient…

Physics of myocardial perfusion imaging (SPECT, PET): Radiotracers, perfusion, blood flow and viability

…SPECT (Single Photon Emission Computed Tomography), radiotracers emit gamma photons directly. These gamma rays are detected by gamma cameras to create tomographic images of the…

Blood pressure

…raised outside it — associated with the same risk as manifest hypertension. Non dipping: a nocturnal fall in pressure of < 10% of the daytime value…

🟠 Mean arterial pressure (MAP) calculator

…Hemodynamic determinants of MAP Hemodynamically, MAP is influenced by cardiac output (CO) and systemic vascular resistance (SVR), as described by the relationship: MAP = (CO…

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