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Left Main Coronary Artery Disease: Revascularisation Strategy

…a lesion proximal to the first septal perforator of the left anterior descending artery was associated with lower five year survival than a more distal…

Physics of myocardial perfusion imaging (SPECT, PET): Radiotracers, perfusion, blood flow and viability

…radiotracers emit gamma photons directly. These gamma rays are detected by gamma cameras to create tomographic images of the left ventricle. In PET (Positron Emission…

ST-Elevation Myocardial Infarction Complicated by Cardiogenic Shock

…blocker exposure. The incidence of cardiogenic shock complicating STEMI has fallen with prompt reperfusion and reduction of infarct size. Earlier estimates approached 20%, whereas contemporary…

SGLT2 Inhibitors for Cardiovascular and Renal Protection

…Reduction in glomerular hypertension and hyperfiltration Decreased tubular energy demand and oxygen consumption Natriuresis and diuresis Reduction in plasma volume, preload and afterload Lower left…

Ejection fraction (EF): Physiology, Measurement & Clinical Evaluation

…to 69% Lower normal limit 55% Ejection fraction is routinely examined at rest, which does not reveal the functional (maximum) capacity of the left ventricle…

ACE Inhibitors: Initiation, Titration and Creatinine Monitoring

…Discharge Management The STRONG HF trial demonstrated the safety and efficacy of an approach based on starting and titrating oral medical therapy for heart failure…

Hypertensive crisis: drugs and doses

…Condition Overall strategy Common first choices : : : Acute aortic syndrome Immediate rate control and rapid reduction of the systolic blood pressure towards 100 to 120 mmHg…

Interpreting NT-proBNP and BNP in Clinical Decision-Making

…renal sodium and water excretion, and reduction of cardiac fibrosis through activation of the natriuretic peptide A receptor. NT proBNP is an inactive cleavage product…

Alcohol and Cardiovascular Disease

…The resulting mild reduction in blood pressure is often accompanied by a compensatory rise in cardiac output. Although these changes are usually of limited clinical…

Eye examination and corneal foreign body

…the rest. Support your working hand against the patient's zygoma or the bridge of the nose. 4. Approach tangentially from the periphery , never through…

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