…fat and fibrous tissue. This process begins in the epicardium and gradually moves towards the endocardium. As the fibrofatty replacement progresses, the ventricular wall becomes…

…patients with severe aortic stenosis, particularly the low flow, low gradient phenotype, or those undergoing aortic valve replacement [1, 5, 10]. A history of increasing…

…seconds. Case reports have indicated that the risk of high degree AV block and ventricular arrhythmias is greater in patients on digoxin or verapamil, although…

…blood flow appropriate to tissue requirements unless filling pressures are elevated. Consequently, congestion may occur across the full range of left ventricular ejection fraction and…

…and initiation of renal replacement therapy. The study found no significant differences between the two treatment groups with respect to either the primary or secondary…

…after pituitary surgery or radiotherapy, or with suspected suppression of the HPA axis after long term glucocorticoid treatment. A basal morning cortisol in the grey…

…Potassium replacement is not the management of a side effect; it is part of the treatment itself. Indications Salicylate poisoning with symptoms or a rising…

…about suppression of the HPA axis, where a long half life produces more marked suppression. Stress dosing in known adrenal insufficiency A patient with primary…

…with needles in three lengths: short for children and slim limbs, medium for most adults, long for thick soft tissue and for the head of…

…Coimbra R. Open chest versus closed chest cardiopulmonary resuscitation in trauma patients with signs of life upon hospital arrival: a retrospective multicenter study. Crit Care…

…or is there approaching, an indication for dialysis? AKI occurs in about one fifth of adults during a hospital episode in international studies and is…

…on the ventilator. See the article on confusion for the management of delirium in intensive care. Renal replacement therapy Absolute indications: refractory hyperkalaemia, refractory acidosis…

…mL/min/1.73 m² Abnormal urinalysis or renal imaging Risk of progression rises with proteinuria and depends on cause 2 60 mL/min/1…

…g in 1 ml vial. Dilute with 10 ml of normal saline and give by slow injection over 5 10 minutes. Dilute immediately before use…

…In patients with previous myocardial infarction and residual inflammation, defined by hsCRP ≥2 mg/L, it produced a modest reduction in a composite of cardiovascular…

…Valve replacement can be performed with biological or mechanical prostheses. The former is preferred due to the lower risk of thrombosis and evidence demonstrating long…