…of Cardiac Amyloidosis Demographic and Clinical Context Cardiac amyloidosis should be suspected in patients older than 65 years presenting with heart failure and increased left…

…after pituitary surgery or radiotherapy, or with suspected suppression of the HPA axis after long term glucocorticoid treatment. A basal morning cortisol in the grey…

…blood flow appropriate to tissue requirements unless filling pressures are elevated. Consequently, congestion may occur across the full range of left ventricular ejection fraction and…

…the reason for which remains elusive. Gene mutations can be confirmed in roughly 60% of individuals with ARVC. Mutations in the desmosomal gene PKP2 is…

…and initiation of renal replacement therapy. The study found no significant differences between the two treatment groups with respect to either the primary or secondary…

…with needles in three lengths: short for children and slim limbs, medium for most adults, long for thick soft tissue and for the head of…

…Potassium replacement is not the management of a side effect; it is part of the treatment itself. Indications Salicylate poisoning with symptoms or a rising…

…about suppression of the HPA axis, where a long half life produces more marked suppression. Stress dosing in known adrenal insufficiency A patient with primary…

…atrial fibrillation with impulses conducted via an accessory pathway [see Wolff Parkinson White Syndrome]); blocking AV node conduction may result in accelerated transmission of atrial…

…with lower temperatures. Electrolyte replacement. Large infusions of fluids are typically needed. Table 1. Grading of hyperthermia. Body temperature should decrease at a rate of…

…or a creatinine of at least 353.6 µmol/L, or renal replacement therapy started Below 0.3 mL/kg/h for at least 24…

…on the ventilator. See the article on confusion for the management of delirium in intensive care. Renal replacement therapy Absolute indications: refractory hyperkalaemia, refractory acidosis…

…mL/min/1.73 m² Abnormal urinalysis or renal imaging Risk of progression rises with proteinuria and depends on cause 2 60 mL/min/1…

…g in 1 ml vial. Dilute with 10 ml of normal saline and give by slow injection over 5 10 minutes. Dilute immediately before use…

…In patients with previous myocardial infarction and residual inflammation, defined by hsCRP ≥2 mg/L, it produced a modest reduction in a composite of cardiovascular…

…Valve replacement can be performed with biological or mechanical prostheses. The former is preferred due to the lower risk of thrombosis and evidence demonstrating long…