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Sepsis and septic shock: quick reference for the first hour

…host response to infection. Clinically this usually corresponds to an acute increase in the SOFA score of at least 2 points. Septic shock is the…

Bone marrow aspiration and biopsy

…Aspirate and biopsy answer different questions and do not replace one another: the aspirate shows cellular morphology and provides material for flow cytometry and genetics…

Anaphylaxis: quick reference for emergency management

…corticosteroids, inhaled bronchodilators and nebulised adrenaline never replace intramuscular adrenaline [1,2]. Delayed administration of adrenaline is associated with more severe and more protracted reactions…

De-escalation and Shortened Dual Antiplatelet Therapy in Patients at High Bleeding Risk

…least one major criterion or two minor criteria. The source material does not provide the individual ARC HBR criteria. Modification of antiplatelet therapy may involve:…

Massive haemorrhage and transfusion: quick reference

…and an increased transfusion requirement. Pregnancy, medication and arrhythmia affect its interpretation. The shock index must never replace clinical assessment [1]. In trauma, the AB

Transcutaneous and transvenous pacing

…adrenaline or dopamine according to local practice, and does not replace pacing when the patient is markedly unstable. Transcutaneous pacing Equipment A defibrillator with a…

Interpreting NT-proBNP and BNP in Clinical Decision-Making

…transferred directly to patients with less acute outpatient symptoms. Natriuretic peptides supplement, rather than replace, clinical assessment. The result should be integrated with the history…

Assessing left ventricular systolic function

…greater precision in the calculation of ejection fraction, and 3D measurements will presumably replace 2D measurements in the future. Cardiac MRI (magnetic resonance imaging) is…

M-mode (motion mode) echocardiography

…mode was previously the dominating modality in echocardiography. Although it has now largely been replaced by 2D echocardiography, it is still used in clinical practice…

Arrhythmogenic Right Ventricular Cardiomyopathy / Dysplasia (ARVC, ARVD)

…is defined by the gradual loss of myocardial cells, which are replaced by fat and fibrous tissue. This process begins in the epicardium and gradually…

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