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Sepsis and septic shock: quick reference for the first hour

…MAP remains below 65 mmHg or the hypotension is marked. Do not wait for a central venous catheter Continuously Reassess the mental state, capillary refill…

Dual Antiplatelet Therapy Duration After Acute Coronary Syndromes and Elective Percutaneous Coronary Intervention

…DAPT is generally a temporary strategy. At an appropriate point, it is usually replaced by single antiplatelet therapy (SAPT), most often aspirin. In selected patients…

Bone marrow aspiration and biopsy

Procedurer Aspirate and biopsy answer different questions and do not replace one another: the aspirate shows cellular morphology and provides material for flow cytometry and…

Anaphylaxis: quick reference for emergency management

…corticosteroids, inhaled bronchodilators and nebulised adrenaline never replace intramuscular adrenaline [1,2]. Delayed administration of adrenaline is associated with more severe and more protracted reactions…

De-escalation and Shortened Dual Antiplatelet Therapy in Patients at High Bleeding Risk

…bleeding risk. These strategies are intended primarily to reduce bleeding rather than to replace the default 12 month regimen in the general ACS population. Clinical…

Massive haemorrhage and transfusion: quick reference

…and an increased transfusion requirement. Pregnancy, medication and arrhythmia affect its interpretation. The shock index must never replace clinical assessment [1]. In trauma, the AB

Transcutaneous and transvenous pacing

…adrenaline or dopamine according to local practice, and does not replace pacing when the patient is markedly unstable. Transcutaneous pacing Equipment A defibrillator with a…

Interpreting NT-proBNP and BNP in Clinical Decision-Making

…transferred directly to patients with less acute outpatient symptoms. Natriuretic peptides supplement, rather than replace, clinical assessment. The result should be integrated with the history…

Assessing left ventricular systolic function

…greater precision in the calculation of ejection fraction, and 3D measurements will presumably replace 2D measurements in the future. Cardiac MRI (magnetic resonance imaging) is…

M-mode (motion mode) echocardiography

…mode was previously the dominating modality in echocardiography. Although it has now largely been replaced by 2D echocardiography, it is still used in clinical practice…

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