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Bone marrow aspiration and biopsy

…Aspirate and biopsy answer different questions and do not replace one another: the aspirate shows cellular morphology and provides material for flow cytometry and genetics…

Anaphylaxis: quick reference for emergency management

…suspected. Do not wait for a complete diagnosis or for grading. Antihistamines, corticosteroids, inhaled bronchodilators and nebulised adrenaline never replace intramuscular adrenaline [1,2]. Delayed…

De-escalation and Shortened Dual Antiplatelet Therapy in Patients at High Bleeding Risk

…The standard post ACS regimen is DAPT for 12 months, generally consisting of low dose aspirin and a potent P2Y12 inhibitor, preferentially prasugrel or ticagrelor…

Massive haemorrhage and transfusion: quick reference

…haemostatic capacity, but it cannot compensate for an uncontrolled source of bleeding. Minimise the time to surgery, endoscopy, an obstetric procedure or angiographic intervention. Summon…

Transcutaneous and transvenous pacing

…pacing: burns or wounds in the area where the pads would go. Transvenous pacing: the relative contraindications are the same as for a central venous…

Interpreting NT-proBNP and BNP in Clinical Decision-Making

…in the emergency department for acute dyspnoea should not be transferred directly to patients with less acute outpatient symptoms. Natriuretic peptides supplement, rather than replace…

Assessing left ventricular systolic function

…3D measurements will presumably replace 2D measurements in the future. Cardiac MRI (magnetic resonance imaging) is considered the gold standard for the calculation of ejection…

M-mode (motion mode) echocardiography

…mode was previously the dominating modality in echocardiography. Although it has now largely been replaced by 2D echocardiography, it is still used in clinical practice…

Arrhythmogenic Right Ventricular Cardiomyopathy / Dysplasia (ARVC, ARVD)

…is defined by the gradual loss of myocardial cells, which are replaced by fat and fibrous tissue. This process begins in the epicardium and gradually…

Tricuspid stenosis

…accompanied by aortic or mitral disease (most commonly mitral stenosis). Simultaneous tricuspid regurgitation is also common. Echocardiography Echocardiography has replaced catheterization for the assessment of…

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