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Injection technique — intramuscular, subcutaneous and intradermal

…and tempts the operator to inject too high. 2. Palpate the acromion . The injection site lies 2–3 fingerbreadths (about 5 cm) below the lower…

Hyperkalaemia: quick reference for emergency treatment

…urine output and ask when the patient last passed urine. Contact intensive care in circulatory compromise, serious arrhythmia, marked QRS widening, a sine wave pattern…

In-Stent Restenosis: Mechanisms and Treatment

…disease arising after percutaneous coronary intervention (PCI). In contemporary practice, ISR remains the most frequent cause of PCI failure, despite its substantially lower incidence with…

Opioid therapy in severe pain

…Postoperative pain. Cancer related pain and pain in the palliative phase. Severe breathlessness in the palliative phase (at lower doses than for pain). An opioid…

Acute Coronary Syndrome: Definitions and Initial Triage

…longer episodes, a lower threshold for provocation, or symptoms that awaken the patient from sleep. Initial symptoms of NSTEMI and UA may be similar. NSTEMI…

Interpreting NT-proBNP and BNP in Clinical Decision-Making

…markers of myocardial wall stress. They are released principally by ventricular cardiomyocytes in response to increased transmural stress and ventricular stretch. Atrial natriuretic peptide is…

High-Sensitivity Troponin: 0/1-Hour Rule-In and Rule-Out Algorithms

…ischemia and infarction Definition and Pathophysiological Basis High sensitivity cardiac troponin (hs cTn) assays detect circulating troponin released from injured cardiomyocytes at substantially lower concentrations…

Unstable Angina: Definition and Contemporary Management

…infarction (AMI), in which myocardial ischaemia is accompanied by cardiomyocyte necrosis and cardiac troponin release meeting the criteria of the universal definition of MI. Clinically…

Gastric lavage and activated charcoal

…including carbamazepine, theophylline and quinine. Repeated dosing may also be appropriate after large ingestions of modified release preparations. Contraindications Measure Contraindication : : Medicinal charcoal A reduced…

Poisoning: quick reference for antidotes and initial management

…with modified release preparations, mixed poisoning, pregnancy, children, a need for an antidote or dialysis, and whenever the clinical course deviates from what was expected…

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