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Antiplatelet Therapy in Secondary Prevention After Myocardial Infarction

…recurrent coronary occlusion, and stent thrombosis. Aspirin inhibits the cyclooxygenase 1 pathway, whereas P2Y12 receptor antagonists inhibit a separate platelet activation pathway. The principal oral…

Dual Antiplatelet Therapy Duration After Acute Coronary Syndromes and Elective Percutaneous Coronary Intervention

Myocardial ischemia and infarction Pharmacology & dosing Definition and pathophysiology Dual antiplatelet therapy (DAPT) is the combined use of aspirin and an oral P2Y12 receptor inhibitor…

De-escalation and Shortened Dual Antiplatelet Therapy in Patients at High Bleeding Risk

…In the setting of acute coronary syndrome (ACS), DAPT is used to reduce recurrent myocardial infarction, stent thrombosis and other ischemic events after coronary angiography…

Oesophageal ECG

…are concealed. A recurrent unclear wide or narrow complex tachycardia in which the mechanism needs to be documented before referral to an arrhythmia unit. Assessment…

Reduction of dislocations

…miss a posterior dislocation. The exceptions are an obvious recurrent dislocation in a patient with known instability and a low energy mechanism, and a neurovascularly…

Empirical antibiotic therapy: quick reference for common infections

…days Hospital acquired pneumonia, non severe cefotaxime 1–2 g × 3 IV 8 days including oral step down Hospital acquired pneumonia, severe piperacillin–tazobactam 4…

Atrial fibrillation: ECG, classification, causes, risk factors & management

…acute myocardial infarction, pericarditis/myocarditis or pulmonary embolism is often a reversible arrhythmia with low risk of recurrence. Atrial fibrillation in other circumstances (particularly those…

In-Stent Restenosis: Mechanisms and Treatment

Myocardial ischemia and infarction Definition and Clinical Significance In stent restenosis (ISR) is recurrent narrowing within a previously implanted coronary stent. It represents a form…

Ischemic Cardiomyopathy: Myocardial Viability Assessment and Revascularization

…Heart failure (HF) symptoms may result from several overlapping processes: Recurrent or extensive MI with necrosis and scar formation Diffuse myocardial fibrosis Reversible ischemic dysfunction…

Risk Factor Modification: The Evidence Base for Primary Prevention

…and from secondary prevention, which addresses patients with established disease to reduce recurrent events and mortality. Risk factor modification is therefore directed at identifying individuals…

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